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Journal of General Surgery for Clinicians    2023, 11 (4): 54-.   Abstract （134）            Knowledge map    Save Related Articles | Metrics

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Journal of General Surgery for Clinicians    2023, 11 (2): 43-.   Abstract （111）            Knowledge map    Save Related Articles | Metrics

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Systematic overall nursing effect on the influence of postoperative edema and quality of life after surgery of perianal abscess CHEN Jing, LIU Xinxin, ZHOU Dongfeng Journal of General Surgery for Clinicians    2023, 11 (2): 54-.   Abstract （111）            Knowledge map    Save Objective To explore the effect of systematic holistic nursing on postoperative wound edema and quality of life in patients with perianal abscess. Method From January 2019 to January 2020, there were 64 patients with perianal abscess surgery treated in Municipal Hospital of Qingdao. They were divided into observation groups and control groups according to the random digital table method. The control group is given conventional nursing, and the observation group gives systematic overall care. By investigating the wound edema situation, patient satisfaction, and quality of life of the two groups after nursing, the perianal wound edema score and health survey scale 36 were used to compare the nursing effects of the two groups. Result The edema scores of the observation group were significantly lower than the control group, and the difference was statistically significant (P ＜ 0.05). The nursing satisfaction rate in the observation group was significantly higher than that in the control group; the physiological function, psychological function, and sleep quality of the observation group Self -care scores are higher than the control group, the differences were significant (P ＜ 0.05). Conclusion Systematic overall care for patients with perianal abscess can effectively improve the effect of surgery, reduce surgical wound edema, improve the quality of life of patients, and improve patient prognosis. Related Articles | Metrics

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Clinical effect of laparoscopic hernioplasty for inguinal hernia GE Xingpeng Journal of General Surgery for Clinicians    2023, 11 (2): 29-.   Abstract （108）            Knowledge map    Save Objective To explore the application value of laparoscopic hernioplasty in the treatment of inguinal hernia, observe the prognosis of patients, and evaluate the treatment effect. Method 80 patients with inguinal hernia admitted to the First People's Hospital of Guannan County, Lianyungang City from May 2021 to May 2022 were randomly divided into two groups by digital table method. The control group (n=40) adopted open tension-free inguinal hernia repair. The study group (n=40) adopted laparoscopic hernia repair. The operation and postoperative related indicators, quality of life scores, pain and sleep scores, and complications of the two groups were compared. Result The operation time of the patients in the study group was longer than that in the control group, the time of getting out of bed and hospitalization were shorter after operation, and the amount of intraoperative bleeding was less than that in the control group, with significant difference (P ＜ 0.05); The pain score, sleep quality score and complication rate in the study group were significantly lower than those in the control group (P ＜ 0.05). Conclusion Laparoscopic hernioplasty for inguinal hernia can improve the clinical symptoms, relieve postoperative pain, improve the quality of life and clinical safety. Related Articles | Metrics

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Advances in finding benefits for colorectal cancer patients with ostomy JI Yanyan, WANG Kaixuan, LI Chang, YANG Lu, ZHANG Dianliang, LIU Zhimei Journal of General Surgery for Clinicians    2023, 11 (2): 24-.   Abstract （100）            Knowledge map    Save With the increasing incidence of colorectal cancer, the number of enterostomy patients is increasing. The psychological problems of enterostomy patients become increasingly prominent. As an important part of positive psychology, benefit discovery can change patients' health behaviors and improve their mental state and quality of life to some extent. In this paper, the research progress of benefit finding in enterostomy patients was summarized from the concept of benefit finding, measurement tools, influencing factors and intervention strategies of benefit finding in enterostomy patients, to provide reference for domestic research on benefit finding in enterostomy patients. Related Articles | Metrics

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Effect of predictive nursing on postoperative nausea and vomiting in patients undergoing thyroid surgery JIANG Qifang, YAN Rong Journal of General Surgery for Clinicians    2023, 11 (2): 46-.   Abstract （99）            Knowledge map    Save Objective To explore the preventive effect of predictive nursing on postoperative nausea and vomiting in patients undergoing thyroid surgery. Method 90 patients who received thyroid surgery in Taixing People's Hospital from April 2020 to April 2021 were selected. According to the results of random odd and even lot drawing, the observation group (odd lot, 45 cases) and the control group (even lot, 45 cases) were divided. The control group took routine care. The observation group implemented predictive care. The incidence of adverse reactions such as nausea and vomiting after surgery in the two groups were observed and counted, The changes of quality of life scores before and after nursing were evaluated. Result The incidences of nausea, vomiting, cough and other adverse reactions in the observation group were significantly lower than those in the control group (P ＜ 0.05); At the same time, the scores of the corresponding items of the quality of life of the patients in the observation group after nursing were higher than those in the control group, with a significant difference (P ＜ 0.05). Conclusion Predictive nursing intervention combined with thyroid surgery can effectively prevent postoperative adverse reactions such as nausea and vomiting, and improve the quality of life of patients. Related Articles | Metrics

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Analysis of the efficacy of linaclotide in patients with functional constipation MA Lin, CHEN Yongqiang, WANG Cai Journal of General Surgery for Clinicians    2023, 11 (2): 11-.   Abstract （98）            Knowledge map    Save Objective To explore the efficacy of linaclotide in treating colonic obstruction in patients with functional constipation. Method From June 2019 to June 2022, 80 patients with colonic obstruction caused by functional constipation who were diagnosed and treated by the Eighth People's Hospital of Qingdao City were randomly divided into a control group and an observation group, with 40 patients in each group. The patients in the control group received routine treatment, including general treatment, anal exhaust, and enema. The observation group was treated with linaclotide on the basis of the control group. Compare the efficacy, frequency of defecation, stool characteristics, abdominal distension, sense of difficulty in defecation, abdominal pain scores, constipation specific quality of life scores, and the occurrence of adverse reactions between the two groups. Result The efficacy of the observation group was 95.00%, significantly higher than that of the control group (77.50%), with a significant difference (P ＜ 0.05). Before treatment, there was no significant difference between the two groups in stool characteristics, defecation frequency, abdominal distension, sense of difficulty in defecation, abdominal pain scores, and constipation specific quality of life scores (P ＞ 0.05); After treatment, the stool characteristics, defecation frequency, and abdominal distension, defecation exertion, abdominal pain scores, and constipation specific quality of life scores of the two groups of patients were significantly increased, and the range of change in the observation group was significantly higher than that in the control group (P ＜ 0.05). During the treatment period, the incidence of adverse reactions was 12.50% in the observation group and 10.00% in the control group, with no significant difference (P ＞ 0.05). The recurrence rate in the observation group was 2.50%, significantly lower than that in the control group (15.00%), with a significant difference (P ＜ 0.05). Conclusion Linaclotide is effective in improving the clinical outcomes of patients with functional constipation and colonic obstruction. Related Articles | Metrics

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Research status of targeted combination with other therapies for primary liver cancer HUANG Dong, CHEN Bin Journal of General Surgery for Clinicians    2023, 11 (2): 20-.   Abstract （94）            Knowledge map    Save Primary liver cancer lacks obvious typical clinical manifestations in the early stage, once obvious symptoms or signs appear, the disease has mostly entered the middle and advanced stages, most of them have lost the opportunity for surgery when they are diagnosed, and some operable patients have early recurrence after surgery and have a poor prognosis. Therefore, non-surgical treatments such as targeted therapy, immunotherapy, radiofrequency ablation, vascular interventional therapy, and traditional Chinese medicine therapy have significant effects on the treatment of liver cancer in the middle and advanced stages, especially targeted therapy for liver cancer is a hot topic now. In this paper, this article reviews the current research progress of targeted therapy for liver cancer and the research status of combination with other treatments. Related Articles | Metrics

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The current status and progress of Global Leadership Initiative on Malnutrition application in the elderly population of general surgery Dai Yao, Ji Yudong, Zhu Qing, Ma Jie, Pang Mingquan, Fan Haiming, Cui Hongyuan, Journal of General Surgery for Clinicians    2024, 12 (1): 26-.   Abstract （93）            Knowledge map    Save The incidence of malnutrition in the elderly population is increasing year by year. It can lead to a decline in physical function, susceptibility to infection, and delayed recovery in elderly people, seriously affecting their quality of life and disease prognosis. Therefore, early identification and diagnosis of malnutrition are of great significance for elderly patients in general surgery. At present, the diagnosis of malnutrition in the elderly population mainly includes the Global Leadership Initiative on Malnutrition (GLIM), Subjective Global Assessment (SGA), and so on. GLIM entered clinical application relatively late, and there is still controversy over whether it can comprehensively reflect the nutritional status of the elderly surgical population. This article mainly explores the current application status of GLIM in diagnosing malnutrition in the elderly population of general surgery, aiming to provide reference for the diagnosis of malnutrition in the elderly. Related Articles | Metrics

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Research progress on the correlation between inflammatory response, insulin resistance and nutritional status in patients with gastric cancer Kong Yu, Zhou Houmin, Lin Wen, Zhou Shaofei Journal of General Surgery for Clinicians    2024, 12 (1): 14-.   Abstract （91）            Knowledge map    Save Gastric cancer is one of the most common malignant tumors in the world, which possessed high morbidity and mortality. The long-term prognosis of patients with gastric cancer is still not ideal. Inflammatory response and insulin resistance of host affect nutritional status and prognosis of patients with gastric cancer. This article aims to analyze the relationship between the level of inflammatory response, insulin resistance and nutritional status in patients with gastric cancer by reviewing relevant literature, and to explore the application value of inflammatory insulin resistance indicator C reactive protein-serum triglycerides and glucose index(CRP-TyG) in clinical evaluation of nutritional status with Gastric cancer, so as to provide references for early detection and intervention of gastric cancer-related malnutrition. Related Articles | Metrics

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The choice and efficacy of treatment for elderly patients with choledocholithiasis combined with cholecystolithiasis LIU Dongdong, YU Anxing, LI Bin Journal of General Surgery for Clinicians    2023, 11 (2): 7-.   Abstract （89）            Knowledge map    Save Objective To explore the choice and efficacy of treatment for elderly patients with choledocholithiasis combined with cholecystolithiasis. Method The elderly patients with cholecystolithiasis and choledocholithiasis diagnosed in Pingdu People's Hospital hospital from February 2017 to November 2019 were selected and randomly divided into the observation group (n=34) and the control group (n=32). The observation group was treated with step-by-step endoscopic sphincteropapillotomy(EST) combined with laparoscopic cholecystectomy (LC), and the control group was treated with LC combined with laparoscopic common bile duct exploration T-tube choledochotomy (LCBDE). The total operation time, indwelling time of drainage tube after operation, intraoperative bleeding, postoperative hospital stay, conversion from laparoscopy to laparotomy, stone removal rate, and postoperative complications (including fever, bile leakage, pancreatitis) were compared between the two groups. Result The total operation time, drainage tube retention time, and postoperative hospitalization time of patients in the observation group were shorter than those in the control group, with less intraoperative bleeding and lower conversion rate to laparotomy in the observation group (P ＜ 0.05). There was no significant difference between the two groups in stone removal rate and postoperative complication rate (P ＞ 0.05). Conclusion Both EST+LC and LC+LCBDE can effectively treat the elderly patients with cholecystolithiasis and choledocholithiasis, but in county hospitals with both technology and equipment, EST+LC is more beneficial for elderly patients with choledocholithiasis and choledocholithiasis. Related Articles | Metrics

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Efficacy and safety analysis of AcoStream thrombus clearance device in the treatment of lower limb deep vein thrombosis ZENG Jinfu, HUANG Yonghao, HUANG Wei, WANG Weiping, HE Dongmei Journal of General Surgery for Clinicians    2023, 11 (3): 61-.   Abstract （89）            Knowledge map    Save 目的 探讨AcoStream 血栓抽吸装置用于下肢深静脉血栓治疗的血栓清除率、显效消肿率以及安全性的影响。方法 选取2019 年1 月至2022 年9 月在化州市人民医院住院治疗的30 例下肢深静脉血栓患者，依据治疗方式的不同分为观察组与对照组，各15 例。观察组患者接受AcoStream 机械血栓抽吸治疗，对照组患者接受单纯导管接触溶栓治疗，比较两组患者术前及术后生活质量、手术相关指标，以及术后相关并发症。结果 观察组患者的术中尿激酶用量少于对照组，患者的小腿和大腿消肿率均高于对照组，且术中溶栓时间、患者住院时间均短于对照组，差异均有显著性（P ＜ 0.05）。但观察组的住院费用显著高于对照组，差异有显著性（P ＜ 0.05）。观察组患者的溶栓有效率以及Ⅱ级和Ⅲ级占比均高于对照组，差异有显著性（P ＜ 0.05）；同时，观察组并发症总发生率[6.67%（1/15）] 显著低于对照组[40.00%（6/15）]，差异有显著性（χ2=4.658，P=0.031）。结论 AcoStream 机械血栓清除装置用于下肢深静脉血栓治疗，安全有效，能提高患者术后生活质量。 Related Articles | Metrics

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Research progress on the mechanism of flora imbalance and pancreatic cancer ZHANG Yuting, ZHANG Yanjun, GONG Zengfeng, PENG Yanni, WEI Jing, WANG Fujuan, YAN Hongfang, MIAO Long Journal of General Surgery for Clinicians    2023, 11 (2): 16-.   Abstract （87）            Knowledge map    Save Pancreatic cancer is one of the malignant tumors with the worst prognosis, with a five-year survival rate of less than 10%, and surgical resection is currently the main treatment method. However, due to the lack of typical clinical manifestations in the early stage of pancreatic cancer, it is usually diagnosed in the late stage of the disease, and most patients lose the opportunity of surgical treatment, while other treatments bring poor efficacy, therefore, early diagnosis of pancreatic cancer is more and more important in clinical practice, and early diagnosis will greatly improve the prognosis of pancreatic cancer patients. More and more studies have shown that the occurrence of pancreatic cancer is related to the alteration of microflora in human body. In this paper, we summarize the current research on human microflora and pancreatic cancer development, and explore the changes of human microflora in the development of pancreatic cancer and the possible mechanisms of action. Human microbes are expected to be markers for early diagnosis of pancreatic cancer, which may open a new pathway for biomarkers and targeted therapy. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2023, 11 (2): 41-.   Abstract （82）            Knowledge map    Save Related Articles | Metrics

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Comparison of the effi cacy and safety of transcatheter arterial chemoembolization and hepatic artery infusion chemotherapy in the treatment of primary liver cancer patients Jiang Zheng, Wen Kailin, Zha Huangqi, Guo Zhengjun, Wu Wenjing Journal of General Surgery for Clinicians    2025, 13 (1): 21-.   Abstract （82）            Knowledge map    Save Objective To compare the application eff ects of transcatheter arterial chemoembolization (TACE) and hepatic artery infusion chemotherapy (HAIC) in the treatment of primary liver cancer patients. Method 80 patients with primary liver cancer admitted to Guangzhou General Hospital of China Life Insurance from January 2023 to January 2024 were selected and randomly divided into two groups, with 40 patients in each group, using a random number table method. The control group was treated with HAIC, while the observation group was treated with TACE. Compare the clinical treatment effi cacy, tumor markers, liver function indicators, and safety between two groups. Result The total eff ective rate of the observation group was 95.00% (38/40), which was higher than that of the control group [80.00%(32/40)], and the diff erence was signifi cant(P ＜ 0.05). Before treatment, there was no signifi cant diff erence in the levels of tumor markers and liver function indicators between the two groups of patients(P ＞ 0.05); After treatment, the serum carcinoembryonic antigen of the observation group patients was (8.17±1.23)μg/L, carbohydrate antigen 125 was (23.45±3.52)U/ml, aspartate aminotransferase was (51.66±5.24)U/L, alanine aminotransferase was (69.36±7.22)U/L, and total bilirubin was (15.79±2.67)μmol/L, which were significantly lower than those of the control group [(9.65±1.14)μg/L, (28.97±3.29)U/ml, (62.70±6.35)U/L, (78.95±9.13)U/L, (19.45±3.06)μmol/L, respectively], and the diff erences were signifi cant (P ＜ 0.05). There was no signifi cant diff erence in the incidence of complications between the two groups of patients (P ＞ 0.05). Conclusion Compared with HAIC, TACE treatment for primary liver cancer can achieve better effi cacy, reduce tumor markers, improve liver function, and has high safety. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2023, 11 (4): 46-.   Abstract （81）            Knowledge map    Save Related Articles | Metrics

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Analysis of the influence of Newman nursing mode on sleep quality and life quality of patients with colon cancer after operation QIAN Wen Journal of General Surgery for Clinicians    2023, 11 (2): 50-.   Abstract （80）            Knowledge map    Save Objective To discuss the effect of Newman's nursing on the postoperative quality of sleep and life of patients with colon cancer. Method 82 patients with colon cancer who were admitted to Nanjing Liuhe District People's Hospital from January 2020 to February 2022 were selected and divided into the control group and the test group according to the random number table. The patients in the control group received routine nursing after operation, and the patients in the test group received Newman nursing after operation. The sleep quality and quality of life of the patients in the two groups were compared before and after nursing. Result In the comparison of sleep quality and quality of life scores, there was no significant difference between the two groups before nursing (P ＞ 0.05); After nursing, the sleep quality score of patients in the test group was lower than that of patients in the control group, and the quality of life score was higher than that of patients in the control group, with a significant difference (P ＜ 0.05). Conclusion Newman nursing can improve the sleep quality and life quality of patients with colon cancer after operation. Related Articles | Metrics

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Comparative study on the effi cacy of minimally invasive rotational mastectomy and traditional surgical treatment for multiple breast masses Luo Jing Journal of General Surgery for Clinicians    2024, 12 (3): 28-.   Abstract （80）            Knowledge map    Save Objective To explore the efficacy of minimally invasive rotational mastectomy and traditional surgical treatment in patients with multiple breast masses. Method 300 female patients with multiple breast masses admitted to Mengzi People’s Hospital from January 2019 to December 2023 were selected and divided into two groups of 150 patients each according to diff erent surgical methods. The control group underwent traditional surgical treatment, while the observation group underwent minimally invasive rotational mastectomy. The perioperative indicators, pain levels, breast appearance improvement rate, and treatment efficacy of the patients were observed. Result The observation group had shorter surgical time, incision healing time, and hospitalizationtime compared to the control group. The intraoperative blood loss was less than that of the control group, and the incision length was shorter than that of the control group, with signifi cant diff erences (P ＜ 0.05). Before treatment, there was no significant difference in VAS scores between the two groups of patients. After treatment, the VAS scores of the observation group were signifi cantly lower than those of the control group, and the diff erence was signifi cant (P ＜ 0.05). The observation group had a higher incidence of excellent breast appearance compared to the control group, and the clinical effi cacy was signifi cantly better (P ＜ 0.05). Conclusion Minimally invasive rotational resection surgery for multiple breast masses has significant therapeutic effects, effectively removing lesions and being superior to traditional treatment methods. It can eff ectively reduce the trauma caused by surgery to the body, shorten the recovery period, and ensure the beauty of the patient’s breast, promoting early recovery of health. Related Articles | Metrics

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Analysis of risk factors for postoperative pulmonary infection in patients undergoing emergency surgery for upper gastrointestinal perforation Ruan Haigang, Wang Chengxing Journal of General Surgery for Clinicians    2025, 13 (1): 11-.   Abstract （77）            Knowledge map    Save Objective To investigate the risk factors for pulmonary infection following emergency surgery for upper gastrointestinal perforation. Method A total of 350 patients diagnosed with upper gastrointestinal per-foration who underwent emergency surgery at our hospital were analyzed. Based on the presence of postoperative pulmonary infection, the patients were divided into an infection group and a non-infection group. Univariate and multivariate logistic regression analyses were conducted to identify the risk factors for pulmonary infection. Result Univariate analysis revealed that the infection group had a higher proportion of patients with a history of smoking (P ＜ 0.001), hypertension (P=0.008), preoperative gastric tube placement (P ＜ 0.001), shock (P ＜ 0.001), dia-betes (P ＜ 0.001) , and reason for perforation (P=0.004)compared to the non-infection group. Multivariate logistic regression analysis indicated that a history of smoking and hypertension are independent risk factors for pulmonary infection following surgery for upper gastrointestinal perforation (P ＜ 0.05). Conclusion A history of smoking and hypertension are signifi cant risk factors for the occurrence of pulmonary infection after emergency surgery for up-per gastrointestinal perforation. Related Articles | Metrics

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Clinical application of bevacizumab combined with chemotherapy in targeted treatment of colorectal cancer Zeng Guowei Journal of General Surgery for Clinicians    2024, 12 (2): 47-.   Abstract （74）            Knowledge map    Save Objective To explore the application effect of bevacizumab combined with chemotherapy in targeted therapy for colorectal cancer. Method A retrospective analysis was conducted on the clinical data of 68 patients with colorectal cancer admitted to Guangzhou Baiyunshan Hospital from June 2022 to June 2023. They were divided into a control group (chemotherapy, 33 cases) and a study group (bevacizumab+chemotherapy, 35 cases) based on diff erent treatment plans. The therapeutic effi cacy, tumor marker levels, and incidence of adverse reactions were compared between the two groups of patients. Result The disease control rate of the study group patients was 94.29%, higher than that of the control group (72.73%), with a significant difference (P ＜ 0.05). Before treatment, there was no signifi cant diff erence in the levels of carbohydrate antigen (CA) 19-9, CA 72-4, and carcinoembryonic antigen between the two groups (P ＞ 0.05); After treatment, the average levels of CA 19-9, CA 72-4, and carcinoembryonic antigen in the study group were signifi cantly lower than those in the control group (P ＜ 0.05). There was no signifi cant diff erence in the total incidence of adverse reactions between the two groups of patients (P ＞ 0.05). Conclusion Bevacizumab combined with chemotherapy can signifi cantly improve the disease control rate of colorectal cancer patients, reduce the level of tumor markers in the body, and there is no increase in the risk of adverse reactions. Related Articles | Metrics