Objective To analyze the risk factors of hemorrhage after endoscopic mucosal resection (EMR) for adenomatous polyps of the large intestine, and to construct a nomogram model of postoperative hemorrhage for adenomatous polyps of the large intestine. Method A total of 300 patients with colorectal adenomatous polyps treated with EMR from January to December 2023 were selected as the modeling group, and 150 patients with colorectal adenomatous polyps treated with EMR from January to June 2024 were selected as the verification group. The patients in the modeling group were divided into bleeding group and non-bleeding group according to whether they experienced postoperative bleeding. Logistic regression analysis was used to screen the risk factors of postoperative bleeding for adenomatous polyps of the large intestine, and R language was used to establish a nomogram model for predicting postoperative bleeding for adenomatous polyps of the large intestine, and finally the model fit and prediction efficiency were evaluated. Result Among the 300 patients, 31 patients had hemorrhage, the incidence of hemorrhage was 10.33%. Clinical data such as smoking history, drinking history, comorbidities, educational level, place of residence, marital status, body mass index, polyp site, number of removed polyps, whether there were tilts and whether there were smooth polyps were compared between the bleeding group and the non-bleeding group , have no significant difference(P ＞ 0.05), while clinical data such as age, sex, polyp size, and whether there were lobed polyps were compared, have a significant difference(P ＜ 0.05). Logistic regression analysis showed that age, sex, polyp size and lobulation were all risk factors for hemorrhage after EMR operation(P ＜ 0.05). The model consistency index (C-index) was 0.851 (95%CI: 0.818-0.884). H-L test showed that the model fit well (χ2=5.365, P=0.305). Receiver operator characteristic curve results showed that the area under the curve value of the nomogram model of hemorrhage after EMR was 0.825. The predicted value of correction curve is close to the actual value. When the prediction threshold probability ranged from 6% to 87%, the net benefit value of nomogram in predicting bleeding after EMR for colorectal adenomatous polyps was higher. Conclusion The nomogram of bleeding risk after endoscopic mucosal resection of adenomatous polyps in the large intestine established in this study is conducive to early clinical identification of high-risk groups for postoperative bleeding, and the nomogram risk prediction model established in this study has guiding significance for medical personnel to make postoperative bleeding prevention and treatment plans.

Objective To analyze the risk factors for postoperative metachronous liver metastasis in young patients with colorectal cancer. Method A retrospective analysis was conducted on the clinical data of 55 young postoperative cases of colorectal cancer with metachronous liver metastasis(occurrence group) and 55 young postoperative cases of colorectal cancer excluding metachronous liver metastasis(no occurrence group)from February 2011 to January 2018 in Jiangmen Central Hospital. Logistic regression analysis was used to identify independent risk factors aff ecting metachronous liver metastasis in young colorectal cancer patients. Result There were significant differences in concurrent liver metastasis, pathological grading, tissue type, depth of infiltration, lymph node metastasis, and family history between the group with and without the occurrence of the disease (P ＜ 0.05). Multivariate analysis showed that synchronous liver metastasis, pathological grading, depth of invasion, and lymph node metastasis were independent risk factors for postoperative metachronous liver metastasis in young colorectal cancer patients (OR=1.881, 1.142, 1.501, 2.734, P ＜ 0.05). Conclusion In clinical practice, the independent risk factors mentioned above can be comprehensively evaluated to reasonably assess the risk of metachronous liver metastasis in patients, in order to improve the survival rate of patients with metachronous liver metastasis.

Objective To analyze the application effect of intracavity electrocardiogram localization technology in infusion port implantation for gastric cancer patients. Method Forty gastric cancer chemotherapy patients admitted to Liyang People's Hospital from July to December 2024 were selected and randomly divided into a control group and an experimental group, with 20 patients in each group, using a random number table method. The control group used intraoperative X-ray fluoroscopy to locate the position of the catheter, while the experimental group patients used intracavitary electrocardiogram positioning technology to locate the catheter position. The positioning effects of different methods on the catheter tip were compared. Result The surgical time of the experimental group was shorter than that of the control group, and the number of punctures, intraoperative catheter adjustments, and X-ray frequency were all less than those of the control group. However, the accuracy was higher than that of the control group, and the differences were significant (P ＜ 0.001). After surgery, The pain score of the experimental group patients was lower than that of the control group, and their quality of life score was higher than that of the control group, with significant differences (P ＜ 0.001). The incidence of complications such as catheter ectopia, puncture site hematoma, infection, pneumothorax, and arrhythmia in the experimental group was significantly lower than that in the control group (P ＜ 0.05). Conclusion The application of intracavitary electrocardiogram positioning technology in infusion port implantation surgery for gastric cancer chemotherapy patients not only reduces the incidence of complications, optimizes intraoperative operation indicators, reduces pain levels, and improves quality of life.

Objective To explore the effect of laparoscopic D2 radical resection for elderly patients with locally advanced gastric cancer. Method 86 elderly patients with locally advanced gastric cancer admitted to Jinhua Hospital affiliated with Wenzhou Medical University from October 2022 to November 2024 were selected and divided into two groups using the coin toss method, with 43 patients in each group. The reference group underwent open D2 radical surgery for gastric cancer, while the study group underwent laparoscopic D2 radical surgery for gastric cancer. Observe and compare the levels of inflammatory factors, stress response indicators, immune function, and postoperative complications between two groups of patients before and after treatment. Result Before treatment, there was no significant difference in the levels of inflammatory factors, stress response indicators, and immune function between the two groups of patients (P ＞ 0.05). After treatment, the levels of inflammatory factors and stress response indicators in the study group were better than those in the control group, and the percentages and ratios of CD8+T cells and CD4+T cells were higher than those in the control group, with significant differences (P ＜ 0.05). The total incidence of postoperative complications in the study group was 2.33%, significantly lower than that in the control group (20.93%), with a significant difference (P=0.007). Conclusion Laparoscopic D2 radical resection for elderly patients with locally advanced gastric cancer can effectively improve the levels of inflammatory factors and stress response indicators, enhance the patient's immune function, and reduce the risk of postoperative complications.

Objective To summarize the surgical experience and techniques in laparoscopic cholecystectomy. Method A retrospective analysis was conducted on the clinical data of 180 patients who underwent laparoscopic cholecystectomy at the Xinjiang Armed Police Corps Hospital from January 2023 to January 2024. Thin layer dissection and suction scraping techniques were used, summarize the patient's surgical related indicators and incidence of complications. Result The average surgical operation time for 180 patients was 40min(35 ～ 110min), the average intraoperative blood loss was 35 ml(5 ～ 50ml), and the average hospitalization time was 7d(5 ～ 8d). All patients successfully underwent laparoscopic cholecystectomy, with 4 cases converted to open surgery. Five cases experienced complications such as bile leakage, bleeding, bile duct stenosis, residual stones, and severe bile duct injury, with a complication rate of 2.78%. Conclusion Due to its complex anatomical structure, laparoscopic cholecystectomy conversion to open surgery is not a failure of laparoscopic surgery. The appropriate surgical approach should be selected based on the patient's basic condition to ensure patient safety and reduce postoperative complications.

Objective To analyze the short-term effect of breast conserving surgery and modified radical surgery for breast cancer on early breast cancer patients. Method 80 cases of early breast cancer patients diagnosed and hospitalized in Chifeng Maternity Hospital from January 2022 to December 2024 were selected, all of whom were women. They were divided into groups by random number table, 40 cases in each group. The control group was treated with modified radical mastectomy for breast cancer, and the observation group was treated with breast conserving surgery+axillary sentinel lymph node biopsy. All patients were followed up for 3 months after surgery to understand the recurrence situation. Result The surgical time and hospitalization time of the observation group were shorter than those of the control group, and the intraoperative blood loss and postoperative drainage volume were less than those of the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the observation group was 7.5%, significantly lower than that in the control group (30.00%), and the difference was significant (P ＜ 0.05). Conclusion Compared with modified radical mastectomy for breast cancer, breast conserving surgery can shorten the operation time and hospital stay of early breast cancer patients, reduce the incidence of incision related complications, and reduce intraoperative bleeding and postoperative drainage volume.

Objective To observe the application and sedative effect of rimazolen in general anesthesia for thyroidectomy. Method 72 patients who underwent thyroidectomy at Jianhu County People's Hospital in Yancheng City from February 2023 to November 2024 were selected and randomly divided into a reference group and a study group, with 36 patients in each group, using a random number table method. Compare the anesthesia effects of two groups of patients. Result Before administration, there was no significant diff erence in the bispectral index and sedation status between the two groups of patients (P ＞ 0.05). After sedation, the bispectral index and modified observer's assessment of alterness/sedation score of patients in the study group were significantly lower than those in the control group at all time points (P ＜ 0.01). The anesthesia time, awakening time, and duration of stay in the anesthesia recovery room of the study group patients were shorter than those of the control group, and the levels of blood glucose, adrenaline, and cortisol were lower than those of the control group at all time points, with significant differences (P ＜ 0.05). The incidence of various adverse events in the study group was lower than that in the control group, and the differences were significant (P ＜ 0.05). Conclusion The application of rimazolen general anesthesia in thyroidectomy is beneficial for controlling the patient's anesthesia recovery time reasonably and eff ectively reducing the risk of adverse reactions.

Objective To evaluate the clinical efficacy and safety of laparoscopic cholecystectomy in the treatment of patients with gallstones and chronic cholecystitis. Method 82 patients with gallstones and chronic cholecystitis admitted to Jurong Maternal and Child Health Hospital from January 2023 to December 2024 were selected and randomly divided into two groups using a random number table. A control group of 41 cases were treated with traditional open abdominal surgery; Observation group of 41 cases, treated with laparoscopic cholecystectomy, compared the surgical indicators and postoperative complications of patients. Result The surgical time and hospitalization time of the observation group were shorter than those of the control group [(61.18±7.52) min vs. (93.35±10.86)min, and (4.31±1.28)d vs. (9.95±2.76)d, respectively]. The intraoperative blood loss was less than that of the control group [(38.91±5.67)ml vs. (90.38±10.46)ml], and the postoperative gastrointestinal function recovery time was earlier than that of the control group [(18.98±5.17)h vs. (42.25±8.92)h], with significant differences(P ＜ 0.001). There were no complications observed in the observation group; There were 5 cases of complications in the control group, including 1 case of abdominal infection, 2 cases of incision infection, and 2 case of bile leakage. There was a significant difference between the groups (χ2=7.318，P=0.017). Conclusion Compared with traditional open surgery, laparoscopic cholecystectomy has better efficacy and higher safety in the treatment of gallstones and chronic cholecystitis.

Objective To study the clinical effect of laparoscopic combined with choledochoscopy in the treatment of patients with gallstones and common bile duct stones. Method 60 patients with cholecystolithiasis and choledocholithiasis who were admitted to the 946 Army Hospital of the People's Liberation Army from January 2023 to December 2024 were selected and grouped according to the random number table. The control group (n=30) underwent laparoscopic common bile duct incision and stone removal surgery for treatment, while the observation group (n=30) underwent laparoscopic combined bile duct exploration and stone removal surgery through the gallbladder duct. The perioperative indicators, levels of infl ammatory factors, stress response indicators, and incidence of postoperative complications were compared between the two groups of patients. Result The intraoperative bleeding volume of patients in the observation group was less than that in the control group, and the hospitalization time, surgical time, incision healing time, fi rst mobilization time, fi rst anal exhaust time, and bowel sound recovery time were all signifi cantly shorter than those in the control group (P ＜ 0.001). Before treatment, there was no signifi cant diff erence in the levels of infl ammatory factors and stress response indicators between the two groups of patients (P ＞ 0.05); After treatment, the levels of T tumor necrosis factor-α, interleukin-6, C reactive protein, and serum amylase in the observation group were lower than those in the control group, and the levels of adrenaline and superoxide dismutase were lower than those in the control group. The levels of malondialdehyde were higher than those in the control group, and the diff erences were signifi cant (P ＜ 0.05). After surgery, there was 1 case of bile leakage and 1 case of infection in the observation group, with a total incidence of complications of 6.67%; The control group experienced 3 cases of bile leakage, 2 cases of abdominal infection, and 2 cases of bile duct bleeding. The total incidence of postoperative complications in the observation group was lower than that in the control group (23.33%), and the diff erence was signifi cant (χ2=5.192, P=0.023). Conclusion The treatment of patients with gallstones combined with common bile duct stones through laparoscopic and choledochoscopy exploration of the gallbladder duct and bile duct can promote patient recovery, reduce the risk of postoperative complications, and improve infl ammatory factors and stress indicators.

Objective To explore the value of combined detection of serum tumor markers alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), and carbohydrate antigen 125 (CA125) in the diagnosis of hepatocellular carcinoma. Method 56 patients with hepatocellular carcinoma admitted to Suqian Integrated Traditional Chinese and Western Medicine Hospital from January 2023 to November 2024 were selected as the liver cancer group, 56 patients with benign liver disease (chronic hepatitis and cirrhosis) were selected as the benign liver disease group, and 56 healthy individuals who underwent physical examinations during the same period were selected as the control group. Detect the levels of serum tumor markers AFP, CEA, and CA125 in three groups, and evaluate the diagnostic efficacy of single and combined detection of AFP, CEA, and CA125. Result The levels of AFP, CEA, and CA125 in the liver cancer group were higher than those in the benign liver disease group and the control group (P ＜ 0.05); The working characteristic curve of the subjects showed that the area under the curve for the combined detection of AFP, CEA, and CA125 was 0.967, with a sensitivity of 91.07% and a specificity of 93.75%, all higher than the detection of AFP, CEA, and CA125 alone. Conclusion The combined detection of AFP, CEA, and CA125 can significantly improve the diagnostic efficacy of hepatocellular carcinoma. Compared with single biomarker detection, the combined detection has higher sensitivity and specificity.

Objective To compare the efficacy of laparoscopic choledochotomy with one-stage suturing and T-tube drainage in the treatment of patients with common bile duct stones. Method 108 patients with common bile duct stones admitted to Xiangshui County People's Hospital in Yancheng City from June 2021 to May 2024 were selected and randomly divided into two groups of 54 each using a random number table method. Both groups underwent laparoscopic common bile duct stone removal surgery, with the control group receiving T-shaped tube drainage and the experimental group receiving primary suture surgery. Compare the surgical outcomes and postoperative recovery indicators, serum inflammatory factor levels, liver function indicators, quality of life, and incidence of postoperative complications between two groups. Result The experimental group had significantly shorter surgical time, postoperative drainage time, intestinal function recovery time, and hospitalization time compared to the control group (P ＜ 0.001). The intraoperative blood output of the experimental group patients was higher than that of the control group, but the difference was not significant (P ＞ 0.05). Before surgery, there was no significant difference in serum inflammatory cytokine levels, liver function indicators, and quality of life between the two groups of patients (P ＞ 0.05). 48 hours after surgery, all inflammatory factor indicators in the experimental group were significantly lower than those in the control group (P ＜ 0.05); The levels of aspartate transaminase and alanine transaminase in the experimental group were lower than those in the control group, and the level of total bilirubin was higher than that in the control group, with signifi cant diff erences (P ＜ 0.001). And the quality of life scores and total scores of the experimental group were significantly higher than those of the control group one month after surgery (P ＜ 0.001). The total incidence rate of patients in the experimental group was 3.70%, which was lower than that in the control group (16.67%), and the difference was significant (P ＜ 0.05). Conclusion Laparoscopic choledochotomy with one-stage suturing is more effective than T-tube drainage in reducing postoperative inflammatory cytokine levels, improving liver function and quality of life, and reducing postoperative complications.

Objective To evaluate the clinical efficacy of laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones. Method 25 patients who received traditional surgical treatment at Fenggang Hospital in Dongguan City from January 2018 to December 2019 were selected as the control group, and 25 patients who received laparoscopic+rigid cholangioscopy ballistic lithotripsy treatment at Fenggang Hospital in Dongguan City from January 2020 to August 2024 were selected as the observation group. The perioperative parameters, immune function, complications, and liver function between the groups were evaluated. Result The surgical time, gastrointestinal function recovery time, and hospitalization time of the observation group were shorter than those of the control group. The intraoperative bleeding volume was less than that of the control group, and the incidence of residual stones was lower than that of the control group, with significant differences (P ＜ 0.01). Before surgery, there was no significant difference in IgA, IgM, IgG levels, and liver function indicators between the two groups of patients (P ＞ 0.05). After surgery, the levels of IgA, IgM, and IgG in the observation group were higher than those in the control group, while the levels of gamma glutamyl-transferase, aspartate transferase, alanine amino-transferase, conjugated bilirubin, total bile acids, and total bilirubin were lower than those in the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the control group was 24.00%, while in the observation group it was 4.00%, with a significant difference (P ＜ 0.001). Conclusion Laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones can optimize perioperative parameters, minimize complications, and improve liver function and bile biochemical indicators.

Objective To analyze the effect of modified laparoscopic triangulation on intestinal function recovery and postoperative pain in patients with sigmoid colon cancer. Method 80 patients with sigmoid colon cancer admitted to Macheng Traditional Chinese Medicine Hospital from June 2021 to June 2024 were selected and divided into a control group and a study group, with 40 patients in each group, according to different treatment methods. The two groups of patients received laparoscopic assisted small incision reconstruction treatment and laparoscopic modified triangular anastomosis treatment, respectively. The treatment effects, intestinal recovery, postoperative pain level, and incidence of complications were compared between the two groups. Result There was no significant difference in the length of intestinal resection and the number of lymph node dissection between the two groups of patients during surgery (P ＞ 0.05). Compared with the control group, the digestive reconstruction time, postoperative feeding time, and anal exhaust time of the study group patients were significantly shorter (P ＜ 0.001); And the pain scores of the study group patients on the first and third day after surgery were significantly lower than those of the control group (P ＜ 0.001), but on the fifth day after surgery, there was no significant difference in pain scores between the two groups (P ＞ 0.05). The total incidence of complications in the control group was 12.50%, which was higher than that in the study group (10.00%), but the difference was not significant (P ＞ 0.05). Conclusion Compared with laparoscopic assisted small incision reconstruction therapy, the use of modified triangular anastomosis under full laparoscopy for the treatment of patients with sigmoid colon cancer has the same effect, and the patient’s intestinal function recovers faster with less postoperative pain.

Objective To investigate the effect of individualized dietary nutrition intervention on the immune function of patients after laparoscopic radical resection of colorectal cancer. Method: Sixty patients with colorectal cancer admitted to Rudong Hospital Affiliated to Nantong University Xinglin College from January 2023 to June 2024 were selected as the research subjects. Divided into an observation group and a control group using envelope method, with 30 cases in each group. The control group received routine nutritional intervention, while the observation group received personalized dietary nutrition intervention on the basis of the control group. The immune function, inflammatory factors, and levels of adverse events were compared between the two groups. Result Before surgery, there was no significant difference in immune function indicators between the two groups of patients (P ＞ 0.05). On postoperative day 7, the levels of CD3⁺and CD4⁺T cells in both groups increased compared to preoperative levels, and the levels of CD3⁺and CD4⁺T cells in the observation group were higher than those in the control group, with significant differences (P ＜ 0.05). On postoperative day 7, the levels of CD8⁺T cells in both groups decreased compared to preoperative levels (P ＜ 0.05); And the observation group was lower than the control group, but there was no significant difference between the groups (P ＞ 0.05). Before surgery, there was no significant difference in the levels of inflammatory factors between the two groups of patients (P ＞ 0.05). On postoperative day 7, the levels of interleukin-6, tumor necrosis factor-α, and C reactive protein in both groups of patients increased compared to preoperative levels, and the observation group was lower than the control group, with significant differences (P ＜ 0.05). The incidence of adverse events in the observation group was lower than that in the control group (6.67% vs. 26.67%), and the difference was significant (χ2=4.320, P=0.038). Conclusion Individualized dietary and nutritional intervention for laparoscopic radical resection of colorectal cancer patients can effectively improve their immune function, reduce inflammatory reactions, and improve prognosis.

Objective To investigate the effect of ultrasound-guided transverse abdominis muscle plane block combined with rectus abdominis muscle block and laryngeal mask general anesthesia on patients undergoing laparoscopic tension-free hernia repair surgery. Method 50 patients who underwent tension-free hernia repair surgery at Xuzhou Mining Group Second Hospital from October 2022 to June 2024 were selected and randomly divided into a control group and an observation group using a random number table, with 25 patients in each group. The control group received transverse abdominis muscle plane block combined with laryngeal mask anesthesia, while the observation group received ascending rectus abdominis muscle block on the basis of the control group, and the anesthesia effect was compared. Result The observation group had better instantaneous blood pressure at the beginning of surgery than the control group, and used less remifentanil during surgery. The visual analogue scale scores at all postoperative time points were lower than those in the control group, and the differences were significant (P ＜ 0.01). Conclusion Ultrasound guided transverse abdominis muscle plane block combined with rectus abdominis muscle block and laryngeal mask general anesthesia can achieve good analgesic effect.

Objective To compare the different therapeutic effects of open tension-free hernia repair and laparoscopic retroperitoneal hernia repair. Method Eighty adult patients with inguinal hernia who received treatment at Caohu People's Hospital of Xiangcheng District in Suzhou City from January 2021 to December 2024 were selected. They were divided into a control group (20 cases) and an observation group (60 cases) using different surgical methods. The control group received open tension-free hernia repair surgery, while the observation group received laparoscopic retroperitoneal hernia repair surgery. The treatment effects of the two groups were compared. Result The observation group had a shorter surgical time and less surgical bleeding compared to the control group, and the duration of pain, postoperative anal exhaust time, and first mobilization time were all shorter than those of the control group, with significant differences (P ≤ 0.001). The incidence of complications in the observation group and the control group was 10.00% and 30.00%, respectively, with a significant difference (P ＜ 0.05). Conclusion Peritoneal hernia repair surgery can improve surgical safety, reduce the risk of surgical complications, and enhance postoperative recovery in adult hernia patients.

Objective To study the effect of external stripping and internal ligation combined with stapled hemorrhoidectomy for the treatment of patients with mixed hemorrhoids and its impact on anal function. Method 60 patients with circular mixed hemorrhoids admitted to Mishan Traditional Chinese Medicine Hospital from January to December 2023 were randomly divided into two groups using a random number table. The control group (n=30) underwent external stripping and internal ligation treatment, while the observation group (n=30) received combined treatment with stapled hemorrhoidectomy on the basis of the control group. The clinical efficacy, recurrence rate, surgical indicators, postoperative complications, postoperative pain and anal function recovery, and anorectal motility indicators at different postoperative times were compared between the two groups of patients. Result The total clinical effective rate of the observation group was higher than that of the control group, the recurrence rate within 1 year was lower than that of the control group, and the postoperative visual analogue scale score and Williams standard rating were both lower than those of the control group, with significant differences (P ＜ 0.05). The surgical time, hospitalization time, and wound healing time of the observation group patients were shorter than those of the control group, and the intraoperative blood loss was less than that of the control group, with significant differences (P ＜ 0.001). One month after surgery, there was no significant difference in anorectal motility indicators between the two groups (P ＞ 0.05); Three months after surgery, both groups showed improvement in anorectal motility indicators compared to one month after surgery, and all indicators in the observation group were better than those in the control group, with significant differences (P ≤ 0.001). The total incidence of postoperative complications in the observation group was 3.33%, which was lower than that in the control group (23.33%), and the difference was significant (P ＜ 0.05). Conclusion Patients with mixed hemorrhoids can improve clinical outcomes, effectively improve anal function, and have a low incidence of complications when treated with external dissection and internal ligation combined with stapled mucosal excision.

Objective To analyze the effect of external exfoliation combined with automatic hemorrhoid ligation on mixed hemorrhoids. Method Select 50 patients with mixed hemorrhoids admitted to Zhongshan Nanqu Hospital from August 2022 to August 2024, and randomly divide them into two groups of 25 patients each using a random number table method. The control group underwent external stripping and internal ligation, while the observation group underwent external stripping combined with automatic hemorrhoid ligation. The treatment effects of the two groups were compared. Result The observation group had significantly shorter surgical time, first bowel movement time, granulation tissue growth time, wound healing time, and hospitalization time compared to the control group (P ＜ 0.01). The maximum anal sphincter pressure in the observation group was significantly higher than that in the control group in both resting and contracting states after surgery (P ＜ 0.001). The pain scores of the observation group patients at 6 hours, 12 hours, 1 day, and 3 days after surgery were significantly lower than those of the control group (P ＜ 0.01). The patients in the observation group had no complications. The patients in the control group had 2 cases of wound edge edema and 1 case of urinary retention. The total incidence of complications in the observation group was lower than that in the control group, but the difference was not significant (χ2=3.192, P=0.074). Conclusion The implementation of external stripping combined with automatic hemorrhoid ligation can improve the anal function of patients with mixed hemorrhoids, reduce the risk of adverse reactions, and alleviate perioperative pain.

Objective To observe the clinical effect of the application of intersphincteric incision and thread drawing surgery for the treatment of high complex anal fistula. Method A total of 90 patients with high complexity anal fistula admitted to Rongxian Integrated Traditional Chinese and Western Medicine Orthopedic Hospital in Yulin City from June 2021 to June 2024 were selected and randomly divided into an observation group of 45 cases and a control group of 45 cases using a random number table. The observation group was treated with intersphincteric incision virtual suture technique, while the control group was treated with conventional incision suture technique. The postoperative anal pain, wound healing time, and efficacy were compared between the two groups of patients. Result The clinical efficacy of the observation group was higher than that of the control group

(100.0% vs. 91.1%), and the difference was significant (P ＜ 0.01). The wound healing time and hospitalization time of the observation group were significantly shorter than those of the control group (P ＜ 0.001). Before surgery, there was no significant difference in incontinence scores between the two groups of patients compared to the control group (P ＞ 0.05); At 3 and 6 months after surgery, the incontinence scores of the observation group were significantly lower than those of the control group (P ＜ 0.05). On postoperative day 1 and 2, the visual analogue scale(VAS) scores of the observation group were significantly lower than those of the control group (P ＜ 0.01), but there was no significant difference in VAS scores between the two groups on postoperative day 7 and 10 (P ＞ 0.05). The incidence of postoperative complications in the observation group was 2.2%, with no patient recurrence. The incidence of complications and recurrence in the observation group were lower than those in the control group, and the differences were significant (P ＜ 0.01). Conclusion The surgical plan of intersphincteric incision with virtual hanging line can reduce the hospitalization period of patients, alleviate their pain, and achieve good short-term and long-term therapeutic effects.

Objective To observe the effect of using ceftriaxone combined with metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period. Method A retrospective analysis was conducted on the clinical data of 80 patients with acute suppurative appendicitis who underwent routine postoperative anti-infective treatment (tranexamic acid+metronidazole) at Guilin Integrated Traditional Chinese and Western Medicine Hospital from May 2023 to May 2024 (control group). The clinical data of 80 patients with acute suppurative appendicitis who underwent postoperative anti-infective treatment with ceftriaxone+metronidazole (observation group) were also reviewed during the same period. Statistics were conducted on the incidence of adverse reactions, levels of inflammatory factors before and after 5d of treatment, body temperature, and length of hospital stay for two groups. Result On the day of surgery, there was no significant difference in body temperature levels between the two groups of patients (P ＞ 0.05). On postoperative day 1, 3, and 5, the temperature levels of patients in the observation group were lower than those in the control group, and the hospitalization time was shorter than that in the control group, with significant differences (P ＜ 0.001). Before treatment, there was no significant difference in the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 between the two groups of patients (P ＞ 0.05). After treatment, the levels of inflammatory factors in both groups of patients improved compared to before treatment, and the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 in the observation group were significantly lower than those in the control group (P ＜ 0.01). The incidence of postoperative adverse reactions in the observation group was lower than that in the control group (3.75% vs. 12.50%), and the difference was significant (P ＜ 0.05). Conclusion The combination of ceftriaxone and metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period can reduce the risk of postoperative adverse reactions, lower levels of inflammatory factors, and shorten hospital stay.

Objective To analyze the application effect of continuous nursing mode in improving the quality of life of pancreatic cancer patients. Method From December 2023 to December 2024, 100 patients with pancreatic tumor were selected from the outpatient and inpatient departments of Japan Friendship Hospital, and were divided into a control group and an observation group according to the random number table, with 50 patients in each group. The control group received routine nursing care, while the observation group received continuous nursing care. The nursing satisfaction before and after 30d of nursing, and quality of life scores of the two groups of patients were compared. Result The nursing satisfaction of the observation group patients was significantly higher than that of the control group, and the difference was significant (P ＜ 0.001). Before intervention, there was no significant difference in the scores of the two groups of patients (P ＞ 0.05). After intervention, the quality of life scores of theobservation group were significantly higher than those of the control group, and the differences were all significant (P ＜ 0.05). Conclusion Continuing nursing care for pancreatic tumor patients can improve nursing satisfaction and enhance quality of life scores.

Objective To explore the application effect of zero defect nursing intervention in patients with gastric bleeding and its impact on self-management level. Method 76 patients with gastric bleeding admitted to the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from August 2023 to September 2024 were selected and divided into two groups using the envelope method, with 38 patients in each group. The control group received routine nursing care, while the observation group received zero defect nursing intervention. Both groups completed 2 weeks of nursing care. Compare the self-care ability, level of hope, and satisfaction between two groups. Result Before the intervention, there was no significant difference in self-care ability and hope level between the two groups of patients (P ＞ 0.05). After intervention, the self-care ability and hope level of both groups of patients were significantly improved compared to before intervention (P ＜ 0.05), and the behavior, cognition, and environmental scores of the observation group were higher than those of the control group. The positive attitude, positive action, intimate relationship, and total score of the observation group were higher than those of the control group, and the diff erences were significant (P ＜ 0.001). After intervention, the satisfaction of the observation group with all aspects was better than that of the control group, and the difference was significant (P ＜ 0.05). Conclusion Zero defect nursing intervention has shown good results in patients with gastric bleeding, improving their self-care ability and helping to enhance their hope level, resulting in higher nursing satisfaction.

Objective To explore the effect of pain nursing intervention on postoperative patients with gallstones. Method 68 patients with gallstones who underwent surgical treatment at Meili People’s Hospital in Changshu City from December 2022 to December 2024 were included and randomly divided into two groups of 34 patients each using a random number table method. The control group received routine nursing care, while the observation group received pain nursing intervention on the basis of the control group. The pain situation, sleep quality, quality of life, and overall satisfaction with nursing care were compared between the two groups. Result Before the surgery, there was no significant difference in visual analogue scale(VAS) scores between the two groups of patients (P ＞ 0.05). However, the VAS scores of the observation group patients at 12 hours, 24 hours, and 48 hours after surgery were significantly lower than those of the control group, and the duration of pain was shorter than that of the control group, with significant differences (P ＜ 0.001). Before nursing, there was no significant difference in the Pittsburgh sleep quality index(PSQI) score and generic quality of life inventory 74(GQOLI-74) score between the two groups of patients (P ＞ 0.05). After nursing, the PSQI score of the observation group was lower than that of the control group, and the GQOLI-74 scores were all higher than those of the control group, with significant differences (P ＜ 0.05). The overall satisfaction rate of nursing care in the observation group was 94.12%, significantly higher than that in the control group (76.47%), and the difference was significant (P=0.037). Conclusion Pain nursing intervention applied to patients with gallstones has significant effects on postoperative rehabilitation, reducing their pain and improving their quality of life and sleep.

Objective To analyze the value of comprehensive nursing intervention in the operating room for patients undergoing thyroidectomy surgery. Method 80 patients who underwent thyroidectomy surgery at the Second People's Hospital of Qingyang City from February 2022 to February 2024 were selected and randomly divided into two groups of 40 each using a random number table. The control group received routine nursing care, while the observation group received comprehensive nursing care in the operating room. The pain scores of the two groups of patients at different time points after surgery were compared, as well as the psychological scores in preoperative visit and 3d after surgery and satisfaction of patients. Result The visual analogue scale scores of the observation group patients at 1, 3, 6, and 12 hours after surgery were lower than those of the control group, and the self-rating depression scale and self-rating anxiety scale scores after nursing were lower than those of the control group. The nursing satisfaction was higher than that of the control group, and the total incidence of complications was lower than that of the control group, with significant differences (P ＜ 0.05). Conclusion Comprehensive nursing intervention in the operating room for patients undergoing thyroidectomy can improve negative emotions and prognosis, and alleviate pain levels.

Objective To analyze the application value of resistance training of exercise rehabilitation in patients with upper limb lymphedema after breast cancer surgery. Method From January 2020 to January 2024, 80 patients with upper limb lymphedema after breast cancer surgery in Rugao Humanity Hospital were selected, all of whom were female patients. They were divided into control group (routine training, n=40) and observation group (resistance training based on sports rehabilitation, n=40) according to different treatment methods. The treatment effect, shoulder joint activity, quality of life, upper limb lymph flow, bilateral upper arm circumference, and bilateral upper limb volume difference of the two groups were statistically analyzed. Result Compared with the control group, the total effective rate of the observation group was higher, and the difference was significant (P ＜ 0.05). Before intervention, there was no significant difference in upper limb lymphedema and quality of life between the two groups of patients (P ＞ 0.05). After intervention, compared with the control group, the observation group had higher upper limb lymphatic flow, smaller bilateral upper arm circumference and bilateral upper limb volume, and higher quality of life scores than the control group, with significant differences (P ＜ 0.001). Compared to the control group, the shoulder joint range of motion in the observation group was significantly higher than that in the control group (P ＜ 0.01). Conclusion The exercise rehabilitation resistance training for patients with upper limb lymphedema after breast cancer surgery can effectively improve the upper limb lymph fl ow, bilateral upper arm circumference, bilateral upper limb volume difference and shoulder joint mobility, and has a positive role in improving the quality of life and clinical efficacy.

Objective To explore the effect of nursing process reengineering combined with comfort care on elderly patients with acute appendicitis. Method 100 elderly patients with acute appendicitis admitted to Shuyang Hospital affiliated with Xuzhou Medical University from January to December 2024 were selected and divided into a study group (n=50) and a basic group (n=50) based on differences in nursing plans. The basic group received basic care, while the research group adopted nursing process reengineering combined with comfort care. Compare the surgical related indicators, psychological status at admission and discharge, and incidence of complications between the two groups. Result The postoperative time to get out of bed, anal exhaust time, and hospitalization time of the study group patients were shorter than those of the baseline group. The number rating scales score at 48 hours after surgery was lower than that of the baseline group, and the differences were significant (P ＜ 0.001). Before intervention, there was no significant difference in the psychological state related scores between the two groups of patients (P ＞ 0.05). After intervention, the patient health questionnaire-9 and generalized anxiety disorder scale, generalized anxiety disorder scale scores of the study group patients were significantly lower than those of the baseline group (P ＜ 0.001). The total incidence of complications in the study group was lower than that in the baseline group, and the difference was significant (P ＜ 0.05). Conclusion The combination of nursing process reengineering and comfort care can improve the surgical related indicators and psychological state of elderly patients with acute appendicitis, and reduce the occurrence of complications.

Objective To analyze the effect of multidimensional nursing intervention based on empowerment theory on postoperative patients with laparoscopic colon cancer. Method A retrospective analysis was conducted on 80 postoperative patients with laparoscopic colon cancer admitted to Changzhou Second People's Hospital from January 2023 to December 2024. According to the intervention method, they were divided into an experimental group (40 cases) and a control group (40 cases). The control group received routine nursing interventions, while the experimental group received multidimensional nursing based on empowerment theory. Compare the recovery status of gastrointestinal function, quality of life, and incidence of postoperative complications between two groups. Result The postoperative anal exhaust time, gastric tube removal time, and normal food recovery time of the experimental group were significantly shorter than those of the control group (P ＜ 0.01). There were no significant differences in the gastrointestinal quality of life index (GIQLI) scores between the two groups before surgery. Postoperatively, the GIQLI scores for both groups improved compared to preoperative levels, with the experimental group showing significantly higher GIQLI scores than the control group (P ＜ 0.05). The total incidence of postoperative complications in the experimental group was lower than that in the control group (2.50% vs. 15.00%), and the difference was significant (χ2=3.913, P=0.048). Conclusion The multidimensional nursing intervention of empowerment theory significantly accelerates the recovery of gastrointestinal function, improves the quality of life, and reduces the risk of postoperative complications in patients with laparoscopic colon cancer surgery.

Objective To analyze and study the construction methods and application effects of the surgical nursing pathway for gallbladder stones under the concept of enhanced recovery after surgery. Method A total of 70 patients with gallbladder stones who underwent surgical treatment and were admitted to Xinghua People's Hospital Affiliated to Yangzhou University from January to December 2024 were selected and grouped according to the random number table method. The odd number group was the control group (35 cases), which received routine surgical care, and the even number group was the observation group (35 cases). Implement surgical nursing pathway intervention based on the concept of accelerated postoperative rehabilitation. Compare the surgical related indicators, quality of life, and incidence of complications between two groups of patients after nursing care. Result The operation time, gastrointestinal recovery time and hospital stay of patients in the observation group were all shorter than those in the control group. The intraoperative blood loss was less than that of patients in the control group. The scores of each item of postoperative 7d quality of life in the observation group were all higher than those in the control group. The differences were all significant (P ＜ 0.05). The incidence of complications in the observation group was 5.71%, which was significantly lower than that in the control group (14.29%), and the difference was significant (P ＜ 0.05). Conclusion The application of the surgical nursing pathway for gallbladder stones under the concept of accelerated postoperative rehabilitation can improve the surgery-related indicators and quality of life of patients and reduce the risk of postoperative complications.

Objective To explore the application of the intervention mode of specialized nurses in the surgery of mixed hemorrhoids patients and its impact on patient pain. Method 132 patients who underwent mixed hemorrhoid surgery at the First Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2022 to April 2024 were selected and divided into two groups using the envelope method, with 66 patients in each group. The control group received routine nursing care, while the observation group received intervention from specialized nurses in addition to the control group. Compare the medical coping strategies, pain levels, psychological stress responses, quality of life, and incidence of complications between two groups of patients. Result Before intervention, there was no significant difference in medical coping modes questionnaire(MCMQ) score, visual analogue scale(VAS) score, perceived stress scale(PSS)-10 score, and short form 36(SF-36) score between the two groups of patients (P ＞ 0.05). After intervention, both groups of patients showed improvement in MCMQ scores compared to before intervention, with reduced pain and psychological stress responses, and improved quality of life, with significant differences (P ＜ 0.05). After intervention, the face score of the observation group patients was higher than that of the control group, and the avoidance and surrender scores were lower than those of the control group. In addition, the VAS score and PSS-10 score were lower than those of the control group, and the SF-36 score was higher than that of the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the observation group was 3.03%, significantly lower than that in the control group (12.12%), with a significant difference (P=0.048). Conclusion The intervention mode of specialized nurses has a good effect on patients with mixed hemorrhoids during surgery, which can improve their medical coping style, alleviate their pain and psychological stress reactions, help improve their quality of life, and reduce the risk of complications.

Objective To explore the application value of “Internet+” nursing service in chronic wound care. Method Ninety patients with chronic wounds who were discharged from Xinghua People's Hospital from February 2023 to February 2024 were selected and randomly divided into two groups of 45 each using a random number table method. The control group used conventional continuous nursing, and the observation group used “Internet+” nursing services. The wound healing, wound care indicators, nursing satisfaction, and wound adverse events of the two groups were compared. Result The effective rate of wound healing in the observation group was 93.33%, significantly higher than that in the control group (73.33%); The number of dressing changes was less than that of the control group, the interval between dressing changes was longer than that of the control group, and the wound healing time was shorter than that of the control group; The nursing satisfaction was significantly higher than that of the control group, and the incidence of wound adverse events such as wound infection, wound erosion, and traumatic dermatitis was lower than that of the control group, with significant differences (P ＜ 0.05). Conclusion The application of “Internet +” nursing service in chronic wound care can effectively promote wound healing, improve wound healing rate, shorten wound healing time, reduce adverse events, and improve patient satisfaction.