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The diagnostic value of combined detection of serum tumor markers alpha fetoprotein, carcinoembryonic antigen, and  carbohydrate antigen 125 for hepatocellular carcinoma Liu Zhaojing Journal of General Surgery for Clinicians    2025, 13 (2): 50-.   Abstract （67）            Knowledge map    Save Objective To explore the value of combined detection of serum tumor markers alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), and carbohydrate antigen 125 (CA125) in the diagnosis of hepatocellular carcinoma. Method 56 patients with hepatocellular carcinoma admitted to Suqian Integrated Traditional Chinese and Western Medicine Hospital from January 2023 to November 2024 were selected as the liver cancer group, 56 patients with benign liver disease (chronic hepatitis and cirrhosis) were selected as the benign liver disease group, and 56 healthy individuals who underwent physical examinations during the same period were selected as the control group. Detect the levels of serum tumor markers AFP, CEA, and CA125 in three groups, and evaluate the diagnostic efficacy of single and combined detection of AFP, CEA, and CA125. Result The levels of AFP, CEA, and CA125 in the liver cancer group were higher than those in the benign liver disease group and the control group (P ＜ 0.05); The working characteristic curve of the subjects showed that the area under the curve for the combined detection of AFP, CEA, and CA125 was 0.967, with a sensitivity of 91.07% and a specificity of 93.75%, all higher than the detection of AFP, CEA, and CA125 alone. Conclusion The combined detection of AFP, CEA, and CA125 can significantly improve the diagnostic efficacy of hepatocellular carcinoma. Compared with single biomarker detection, the combined detection has higher sensitivity and specificity. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2025, 13 (2): 146-.   Abstract （50）            Knowledge map    Save Related Articles | Metrics

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Clinical application of laparoscopic combined with choledochoscopy in the treatment of gallstones and common bile duct stones Liang Xiaolei Journal of General Surgery for Clinicians    2025, 13 (2): 45-.   Abstract （47）            Knowledge map    Save Objective To study the clinical effect of laparoscopic combined with choledochoscopy in the treatment of patients with gallstones and common bile duct stones. Method 60 patients with cholecystolithiasis and choledocholithiasis who were admitted to the 946 Army Hospital of the People's Liberation Army from January 2023 to December 2024 were selected and grouped according to the random number table. The control group (n=30) underwent laparoscopic common bile duct incision and stone removal surgery for treatment, while the observation group (n=30) underwent laparoscopic combined bile duct exploration and stone removal surgery through the gallbladder duct. The perioperative indicators, levels of infl ammatory factors, stress response indicators, and incidence of postoperative complications were compared between the two groups of patients. Result The intraoperative bleeding volume of patients in the observation group was less than that in the control group, and the hospitalization time, surgical time, incision healing time, fi rst mobilization time, fi rst anal exhaust time, and bowel sound recovery time were all signifi cantly shorter than those in the control group (P ＜ 0.001). Before treatment, there was no signifi cant diff erence in the levels of infl ammatory factors and stress response indicators between the two groups of patients (P ＞ 0.05); After treatment, the levels of T tumor necrosis factor-α, interleukin-6, C reactive protein, and serum amylase in the observation group were lower than those in the control group, and the levels of adrenaline and superoxide dismutase were lower than those in the control group. The levels of malondialdehyde were higher than those in the control group, and the diff erences were signifi cant (P ＜ 0.05). After surgery, there was 1 case of bile leakage and 1 case of infection in the observation group, with a total incidence of complications of 6.67%; The control group experienced 3 cases of bile leakage, 2 cases of abdominal infection, and 2 cases of bile duct bleeding. The total incidence of postoperative complications in the observation group was lower than that in the control group (23.33%), and the diff erence was signifi cant (χ2=5.192, P=0.023). Conclusion The treatment of patients with gallstones combined with common bile duct stones through laparoscopic and choledochoscopy exploration of the gallbladder duct and bile duct can promote patient recovery, reduce the risk of postoperative complications, and improve infl ammatory factors and stress indicators. Related Articles | Metrics

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Construction of a nomogram prediction model for bleeding risk of colorectal adenomatous polyps after endoscopic mucosal resection Ou Yongding, Wang Peng, Zhang Jiaji Journal of General Surgery for Clinicians    2025, 13 (2): 2-.   Abstract （43）            Knowledge map    Save Objective To analyze the risk factors of hemorrhage after endoscopic mucosal resection (EMR) for adenomatous polyps of the large intestine, and to construct a nomogram model of postoperative hemorrhage for adenomatous polyps of the large intestine. Method A total of 300 patients with colorectal adenomatous polyps treated with EMR from January to December 2023 were selected as the modeling group, and 150 patients with colorectal adenomatous polyps treated with EMR from January to June 2024 were selected as the verification group. The patients in the modeling group were divided into bleeding group and non-bleeding group according to whether they experienced postoperative bleeding. Logistic regression analysis was used to screen the risk factors of postoperative bleeding for adenomatous polyps of the large intestine, and R language was used to establish a nomogram model for predicting postoperative bleeding for adenomatous polyps of the large intestine, and finally the model fit and prediction efficiency were evaluated. Result Among the 300 patients, 31 patients had hemorrhage, the incidence of hemorrhage was 10.33%. Clinical data such as smoking history, drinking history, comorbidities, educational level, place of residence, marital status, body mass index, polyp site, number of removed polyps, whether there were tilts and whether there were smooth polyps were compared between the bleeding group and the non-bleeding group , have no significant difference(P ＞ 0.05), while clinical data such as age, sex, polyp size, and whether there were lobed polyps were compared, have a significant difference(P ＜ 0.05). Logistic regression analysis showed that age, sex, polyp size and lobulation were all risk factors for hemorrhage after EMR operation(P ＜ 0.05). The model consistency index (C-index) was 0.851 (95%CI: 0.818-0.884). H-L test showed that the model fit well (χ2=5.365, P=0.305). Receiver operator characteristic curve results showed that the area under the curve value of the nomogram model of hemorrhage after EMR was 0.825. The predicted value of correction curve is close to the actual value. When the prediction threshold probability ranged from 6% to 87%, the net benefit value of nomogram in predicting bleeding after EMR for colorectal adenomatous polyps was higher. Conclusion The nomogram of bleeding risk after endoscopic mucosal resection of adenomatous polyps in the large intestine established in this study is conducive to early clinical identification of high-risk groups for postoperative bleeding, and the nomogram risk prediction model established in this study has guiding significance for medical personnel to make postoperative bleeding prevention and treatment plans. Related Articles | Metrics

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Clinical analysis of laparoscopic combined with rigid cholangioscopy ballistic lithotripsy for the treatment of patients with liver and bile duct stones Wang Maoqiang, Huang Tao, Zhao Jianbo, Sun Haifeng, Chen Zhengxiu, He Lingsheng, Wang Jianyu, Liang Feng, Liao Jianming, Huang Huanji Journal of General Surgery for Clinicians    2025, 13 (2): 60-.   Abstract （38）            Knowledge map    Save Objective To evaluate the clinical efficacy of laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones. Method 25 patients who received traditional surgical treatment at Fenggang Hospital in Dongguan City from January 2018 to December 2019 were selected as the control group, and 25 patients who received laparoscopic+rigid cholangioscopy ballistic lithotripsy treatment at Fenggang Hospital in Dongguan City from January 2020 to August 2024 were selected as the observation group. The perioperative parameters, immune function, complications, and liver function between the groups were evaluated. Result The surgical time, gastrointestinal function recovery time, and hospitalization time of the observation group were shorter than those of the control group. The intraoperative bleeding volume was less than that of the control group, and the incidence of residual stones was lower than that of the control group, with significant differences (P ＜ 0.01). Before surgery, there was no significant difference in IgA, IgM, IgG levels, and liver function indicators between the two groups of patients (P ＞ 0.05). After surgery, the levels of IgA, IgM, and IgG in the observation group were higher than those in the control group, while the levels of gamma glutamyl-transferase, aspartate transferase, alanine amino-transferase, conjugated bilirubin, total bile acids, and total bilirubin were lower than those in the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the control group was 24.00%, while in the observation group it was 4.00%, with a significant difference (P ＜ 0.001). Conclusion Laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones can optimize perioperative parameters, minimize complications, and improve liver function and bile biochemical indicators. Related Articles | Metrics

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The therapeutic effect of external stripping and internal ligation combined with stapler hemorrhoidectomy on patients with mixed hemorrhoids and its impact on anal function Zhuang Guodong, Wu Liwei Journal of General Surgery for Clinicians    2025, 13 (2): 81-.   Abstract （38）            Knowledge map    Save Objective To study the effect of external stripping and internal ligation combined with stapled hemorrhoidectomy for the treatment of patients with mixed hemorrhoids and its impact on anal function. Method 60 patients with circular mixed hemorrhoids admitted to Mishan Traditional Chinese Medicine Hospital from January to December 2023 were randomly divided into two groups using a random number table. The control group (n=30) underwent external stripping and internal ligation treatment, while the observation group (n=30) received combined treatment with stapled hemorrhoidectomy on the basis of the control group. The clinical efficacy, recurrence rate, surgical indicators, postoperative complications, postoperative pain and anal function recovery, and anorectal motility indicators at different postoperative times were compared between the two groups of patients. Result The total clinical effective rate of the observation group was higher than that of the control group, the recurrence rate within 1 year was lower than that of the control group, and the postoperative visual analogue scale score and Williams standard rating were both lower than those of the control group, with significant differences (P ＜ 0.05). The surgical time, hospitalization time, and wound healing time of the observation group patients were shorter than those of the control group, and the intraoperative blood loss was less than that of the control group, with significant differences (P ＜ 0.001). One month after surgery, there was no significant difference in anorectal motility indicators between the two groups (P ＞ 0.05); Three months after surgery, both groups showed improvement in anorectal motility indicators compared to one month after surgery, and all indicators in the observation group were better than those in the control group, with significant differences (P ≤ 0.001). The total incidence of postoperative complications in the observation group was 3.33%, which was lower than that in the control group (23.33%), and the difference was significant (P ＜ 0.05). Conclusion Patients with mixed hemorrhoids can improve clinical outcomes, effectively improve anal function, and have a low incidence of complications when treated with external dissection and internal ligation combined with stapled mucosal excision. Related Articles | Metrics

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Summary and exploration of laparoscopic cholecystectomy surgery experience Wang Zuo, Ma Ruibin, Guo Zhihao, Yu Xiaoping, Jiao Hui Journal of General Surgery for Clinicians    2025, 13 (2): 32-.   Abstract （37）            Knowledge map    Save Objective To summarize the surgical experience and techniques in laparoscopic cholecystectomy. Method A retrospective analysis was conducted on the clinical data of 180 patients who underwent laparoscopic cholecystectomy at the Xinjiang Armed Police Corps Hospital from January 2023 to January 2024. Thin layer dissection and suction scraping techniques were used, summarize the patient's surgical related indicators and incidence of complications. Result The average surgical operation time for 180 patients was 40min(35 ～ 110min), the average intraoperative blood loss was 35 ml(5 ～ 50ml), and the average hospitalization time was 7d(5 ～ 8d). All patients successfully underwent laparoscopic cholecystectomy, with 4 cases converted to open surgery. Five cases experienced complications such as bile leakage, bleeding, bile duct stenosis, residual stones, and severe bile duct injury, with a complication rate of 2.78%. Conclusion Due to its complex anatomical structure, laparoscopic cholecystectomy conversion to open surgery is not a failure of laparoscopic surgery. The appropriate surgical approach should be selected based on the patient's basic condition to ensure patient safety and reduce postoperative complications. Related Articles | Metrics

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The effect of ceftriaxone combined with metronidazole in the perioperative anti infective treatment of acute suppurative appendicitis Qin Jia, He Qingshi Journal of General Surgery for Clinicians    2025, 13 (2): 93-.   Abstract （34）            Knowledge map    Save Objective To observe the effect of using ceftriaxone combined with metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period. Method A retrospective analysis was conducted on the clinical data of 80 patients with acute suppurative appendicitis who underwent routine postoperative anti-infective treatment (tranexamic acid+metronidazole) at Guilin Integrated Traditional Chinese and Western Medicine Hospital from May 2023 to May 2024 (control group). The clinical data of 80 patients with acute suppurative appendicitis who underwent postoperative anti-infective treatment with ceftriaxone+metronidazole (observation group) were also reviewed during the same period. Statistics were conducted on the incidence of adverse reactions, levels of inflammatory factors before and after 5d of treatment, body temperature, and length of hospital stay for two groups. Result On the day of surgery, there was no significant difference in body temperature levels between the two groups of patients (P ＞ 0.05). On postoperative day 1, 3, and 5, the temperature levels of patients in the observation group were lower than those in the control group, and the hospitalization time was shorter than that in the control group, with significant differences (P ＜ 0.001). Before treatment, there was no significant difference in the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 between the two groups of patients (P ＞ 0.05). After treatment, the levels of inflammatory factors in both groups of patients improved compared to before treatment, and the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 in the observation group were significantly lower than those in the control group (P ＜ 0.01). The incidence of postoperative adverse reactions in the observation group was lower than that in the control group (3.75% vs. 12.50%), and the difference was significant (P ＜ 0.05). Conclusion The combination of ceftriaxone and metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period can reduce the risk of postoperative adverse reactions, lower levels of inflammatory factors, and shorten hospital stay. Related Articles | Metrics

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Exploration of the value of pain care intervention in improving postoperative quality of life for patients with gallstones Gu Yue Journal of General Surgery for Clinicians    2025, 13 (2): 106-.   Abstract （33）            Knowledge map    Save Objective To explore the effect of pain nursing intervention on postoperative patients with gallstones. Method 68 patients with gallstones who underwent surgical treatment at Meili People’s Hospital in Changshu City from December 2022 to December 2024 were included and randomly divided into two groups of 34 patients each using a random number table method. The control group received routine nursing care, while the observation group received pain nursing intervention on the basis of the control group. The pain situation, sleep quality, quality of life, and overall satisfaction with nursing care were compared between the two groups. Result Before the surgery, there was no significant difference in visual analogue scale(VAS) scores between the two groups of patients (P ＞ 0.05). However, the VAS scores of the observation group patients at 12 hours, 24 hours, and 48 hours after surgery were significantly lower than those of the control group, and the duration of pain was shorter than that of the control group, with significant differences (P ＜ 0.001). Before nursing, there was no significant difference in the Pittsburgh sleep quality index(PSQI) score and generic quality of life inventory 74(GQOLI-74) score between the two groups of patients (P ＞ 0.05). After nursing, the PSQI score of the observation group was lower than that of the control group, and the GQOLI-74 scores were all higher than those of the control group, with significant differences (P ＜ 0.05). The overall satisfaction rate of nursing care in the observation group was 94.12%, significantly higher than that in the control group (76.47%), and the difference was significant (P=0.037). Conclusion Pain nursing intervention applied to patients with gallstones has significant effects on postoperative rehabilitation, reducing their pain and improving their quality of life and sleep. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2025, 13 (2): 142-.   Abstract （30）            Knowledge map    Save Related Articles | Metrics

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Analysis of risk factors for metachronous liver metastasis after surgery in young patients with colorectal cancer Li Yanfen, Zhang Yuhao, Zhou Chaorong, Wang Chengxing Journal of General Surgery for Clinicians    2025, 13 (2): 13-.   Abstract （29）            Knowledge map    Save Objective To analyze the risk factors for postoperative metachronous liver metastasis in young patients with colorectal cancer. Method A retrospective analysis was conducted on the clinical data of 55 young postoperative cases of colorectal cancer with metachronous liver metastasis(occurrence group) and 55 young postoperative cases of colorectal cancer excluding metachronous liver metastasis(no occurrence group)from February 2011 to January 2018 in Jiangmen Central Hospital. Logistic regression analysis was used to identify independent risk factors aff ecting metachronous liver metastasis in young colorectal cancer patients. Result There were significant differences in concurrent liver metastasis, pathological grading, tissue type, depth of infiltration, lymph node metastasis, and family history between the group with and without the occurrence of the disease (P ＜ 0.05). Multivariate analysis showed that synchronous liver metastasis, pathological grading, depth of invasion, and lymph node metastasis were independent risk factors for postoperative metachronous liver metastasis in young colorectal cancer patients (OR=1.881, 1.142, 1.501, 2.734, P ＜ 0.05). Conclusion In clinical practice, the independent risk factors mentioned above can be comprehensively evaluated to reasonably assess the risk of metachronous liver metastasis in patients, in order to improve the survival rate of patients with metachronous liver metastasis. Related Articles | Metrics

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Progress in endoscopic diagnosis and treatment of gastrointestinal stromal tumors Teng Shuai, Li Zhenkai, Zhai Zhenzhen Journal of General Surgery for Clinicians    2025, 13 (2): 24-.   Abstract （28）            Knowledge map    Save Gastrointestinal stromal tumor (GIST) is a common mesenchymal tumor of the gastrointestinal tract, with potential malignancy, non-specific clinical manifestations, and difficult preoperative diagnosis. In the past, surgical treatment was mainly relied on. In recent years, the development of endoscopic examination and endoscopic ultrasound technology has improved the diagnostic and pathological tissue acquisition capabilities of GIST. Endoscopic treatment has obvious advantages. This article aims to review the endoscopic diagnosis and treatment methods of GIST. Related Articles | Metrics

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Analysis of the impact of multidimensional nursing interventions based on empowerment theory on postoperative patients with laparoscopic colon cancer Pu Chengyan, Xu Yajing, Song Peng Journal of General Surgery for Clinicians    2025, 13 (2): 123-.   Abstract （28）            Knowledge map    Save Objective To analyze the effect of multidimensional nursing intervention based on empowerment theory on postoperative patients with laparoscopic colon cancer. Method A retrospective analysis was conducted on 80 postoperative patients with laparoscopic colon cancer admitted to Changzhou Second People's Hospital from January 2023 to December 2024. According to the intervention method, they were divided into an experimental group (40 cases) and a control group (40 cases). The control group received routine nursing interventions, while the experimental group received multidimensional nursing based on empowerment theory. Compare the recovery status of gastrointestinal function, quality of life, and incidence of postoperative complications between two groups. Result The postoperative anal exhaust time, gastric tube removal time, and normal food recovery time of the experimental group were significantly shorter than those of the control group (P ＜ 0.01). There were no significant differences in the gastrointestinal quality of life index (GIQLI) scores between the two groups before surgery. Postoperatively, the GIQLI scores for both groups improved compared to preoperative levels, with the experimental group showing significantly higher GIQLI scores than the control group (P ＜ 0.05). The total incidence of postoperative complications in the experimental group was lower than that in the control group (2.50% vs. 15.00%), and the difference was significant (χ2=3.913, P=0.048). Conclusion The multidimensional nursing intervention of empowerment theory significantly accelerates the recovery of gastrointestinal function, improves the quality of life, and reduces the risk of postoperative complications in patients with laparoscopic colon cancer surgery. Related Articles | Metrics

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The construction and application effect of the surgical nursing pathway for gallbladder stones under the concept of enhanced recovery after surgery Han Xiao, Wang Yuxia Journal of General Surgery for Clinicians    2025, 13 (2): 127-.   Abstract （27）            Knowledge map    Save Objective To analyze and study the construction methods and application effects of the surgical nursing pathway for gallbladder stones under the concept of enhanced recovery after surgery. Method A total of 70 patients with gallbladder stones who underwent surgical treatment and were admitted to Xinghua People's Hospital Affiliated to Yangzhou University from January to December 2024 were selected and grouped according to the random number table method. The odd number group was the control group (35 cases), which received routine surgical care, and the even number group was the observation group (35 cases). Implement surgical nursing pathway intervention based on the concept of accelerated postoperative rehabilitation. Compare the surgical related indicators, quality of life, and incidence of complications between two groups of patients after nursing care. Result The operation time, gastrointestinal recovery time and hospital stay of patients in the observation group were all shorter than those in the control group. The intraoperative blood loss was less than that of patients in the control group. The scores of each item of postoperative 7d quality of life in the observation group were all higher than those in the control group. The differences were all significant (P ＜ 0.05). The incidence of complications in the observation group was 5.71%, which was significantly lower than that in the control group (14.29%), and the difference was significant (P ＜ 0.05). Conclusion The application of the surgical nursing pathway for gallbladder stones under the concept of accelerated postoperative rehabilitation can improve the surgery-related indicators and quality of life of patients and reduce the risk of postoperative complications. Related Articles | Metrics

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Analysis of the therapeutic effect of external stripping combined with automatic hemorrhoid ligation in the treatment of mixed hemorrhoids Fan Zhican, Hu Li Journal of General Surgery for Clinicians    2025, 13 (2): 85-.   Abstract （27）            Knowledge map    Save Objective To analyze the effect of external exfoliation combined with automatic hemorrhoid ligation on mixed hemorrhoids. Method Select 50 patients with mixed hemorrhoids admitted to Zhongshan Nanqu Hospital from August 2022 to August 2024, and randomly divide them into two groups of 25 patients each using a random number table method. The control group underwent external stripping and internal ligation, while the observation group underwent external stripping combined with automatic hemorrhoid ligation. The treatment effects of the two groups were compared. Result The observation group had significantly shorter surgical time, first bowel movement time, granulation tissue growth time, wound healing time, and hospitalization time compared to the control group (P ＜ 0.01). The maximum anal sphincter pressure in the observation group was significantly higher than that in the control group in both resting and contracting states after surgery (P ＜ 0.001). The pain scores of the observation group patients at 6 hours, 12 hours, 1 day, and 3 days after surgery were significantly lower than those of the control group (P ＜ 0.01). The patients in the observation group had no complications. The patients in the control group had 2 cases of wound edge edema and 1 case of urinary retention. The total incidence of complications in the observation group was lower than that in the control group, but the difference was not significant (χ2=3.192, P=0.074). Conclusion The implementation of external stripping combined with automatic hemorrhoid ligation can improve the anal function of patients with mixed hemorrhoids, reduce the risk of adverse reactions, and alleviate perioperative pain. Related Articles | Metrics

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Analysis of the therapeutic effect of intersphincteric incision and thread hanging surgery for high complex anal fistula Xie Feng Journal of General Surgery for Clinicians    2025, 13 (2): 88-.   Abstract （27）            Knowledge map    Save Objective To observe the clinical effect of the application of intersphincteric incision and thread drawing surgery for the treatment of high complex anal fistula. Method A total of 90 patients with high complexity anal fistula admitted to Rongxian Integrated Traditional Chinese and Western Medicine Orthopedic Hospital in Yulin City from June 2021 to June 2024 were selected and randomly divided into an observation group of 45 cases and a control group of 45 cases using a random number table. The observation group was treated with intersphincteric incision virtual suture technique, while the control group was treated with conventional incision suture technique. The postoperative anal pain, wound healing time, and efficacy were compared between the two groups of patients. Result The clinical efficacy of the observation group was higher than that of the control group (100.0% vs. 91.1%), and the difference was significant (P ＜ 0.01). The wound healing time and hospitalization time of the observation group were significantly shorter than those of the control group (P ＜ 0.001). Before surgery, there was no significant difference in incontinence scores between the two groups of patients compared to the control group (P ＞ 0.05); At 3 and 6 months after surgery, the incontinence scores of the observation group were significantly lower than those of the control group (P ＜ 0.05). On postoperative day 1 and 2, the visual analogue scale(VAS) scores of the observation group were significantly lower than those of the control group (P ＜ 0.01), but there was no significant difference in VAS scores between the two groups on postoperative day 7 and 10 (P ＞ 0.05). The incidence of postoperative complications in the observation group was 2.2%, with no patient recurrence. The incidence of complications and recurrence in the observation group were lower than those in the control group, and the differences were significant (P ＜ 0.01). Conclusion The surgical plan of intersphincteric incision with virtual hanging line can reduce the hospitalization period of patients, alleviate their pain, and achieve good short-term and long-term therapeutic effects. Related Articles | Metrics

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The impact of laparoscopic D2 radical resection for gastric cancer on elderly patients with locally advanced gastric cancer Zhu Jiani, Li Song, Chen Guoliang, Xia Adong, Tang Jie Journal of General Surgery for Clinicians    2025, 13 (2): 28-.   Abstract （27）            Knowledge map    Save Objective To explore the effect of laparoscopic D2 radical resection for elderly patients with locally advanced gastric cancer. Method 86 elderly patients with locally advanced gastric cancer admitted to Jinhua Hospital affiliated with Wenzhou Medical University from October 2022 to November 2024 were selected and divided into two groups using the coin toss method, with 43 patients in each group. The reference group underwent open D2 radical surgery for gastric cancer, while the study group underwent laparoscopic D2 radical surgery for gastric cancer. Observe and compare the levels of inflammatory factors, stress response indicators, immune function, and postoperative complications between two groups of patients before and after treatment. Result Before treatment, there was no significant difference in the levels of inflammatory factors, stress response indicators, and immune function between the two groups of patients (P ＞ 0.05). After treatment, the levels of inflammatory factors and stress response indicators in the study group were better than those in the control group, and the percentages and ratios of CD8+T cells and CD4+T cells were higher than those in the control group, with significant differences (P ＜ 0.05). The total incidence of postoperative complications in the study group was 2.33%, significantly lower than that in the control group (20.93%), with a significant difference (P=0.007). Conclusion Laparoscopic D2 radical resection for elderly patients with locally advanced gastric cancer can effectively improve the levels of inflammatory factors and stress response indicators, enhance the patient's immune function, and reduce the risk of postoperative complications. Related Articles | Metrics

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Exploring the application effect of ultrasound-guided transverse abdominis muscle plane block combined with rectus abdominis muscle block and laryngeal mask airway general anesthesia in patients undergoing laparoscopic tension-free hernia repair surgery Zhang Kai Journal of General Surgery for Clinicians    2025, 13 (2): 73-.   Abstract （27）            Knowledge map    Save Objective To investigate the effect of ultrasound-guided transverse abdominis muscle plane block combined with rectus abdominis muscle block and laryngeal mask general anesthesia on patients undergoing laparoscopic tension-free hernia repair surgery. Method 50 patients who underwent tension-free hernia repair surgery at Xuzhou Mining Group Second Hospital from October 2022 to June 2024 were selected and randomly divided into a control group and an observation group using a random number table, with 25 patients in each group. The control group received transverse abdominis muscle plane block combined with laryngeal mask anesthesia, while the observation group received ascending rectus abdominis muscle block on the basis of the control group, and the anesthesia effect was compared. Result The observation group had better instantaneous blood pressure at the beginning of surgery than the control group, and used less remifentanil during surgery. The visual analogue scale scores at all postoperative time points were lower than those in the control group, and the differences were significant (P ＜ 0.01). Conclusion Ultrasound guided transverse abdominis muscle plane block combined with rectus abdominis muscle block and laryngeal mask general anesthesia can achieve good analgesic effect. Related Articles | Metrics

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Feasibility analysis of conducting daytime surgery in community health service centers Ma Yaohu, Liu Ning, Zhang Jianjie Journal of General Surgery for Clinicians    2025, 13 (3): 31-.   Abstract （27）            Knowledge map    Save With the development of medical technology and the increasing demand for medical services from patients, the day surgery model is gradually emerging worldwide. This paper takes breast tumor resection surgery as an example to conduct an in-depth analysis of the feasibility of daytime surgery in community health service centers. By elaborating on the concept, characteristics, and current development status of day surgery, this article analyzes the reasons why breast tumor resection surgery is suitable for community health service centers to carry out day surgery, including patient needs, technical feasibility, cost-effectiveness, and other factors. At the same time, it explores the challenges faced by community health service centers in carrying out this day surgery and proposes corresponding response strategies, aiming to provide theoretical basis for community health service centers to expand service scope and improve medical service quality. Related Articles | Metrics

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Effect of rapid rehabilitation nursing on psychological state and pain of patients with modifi ed radical mastectomy for breast cancer Xu Fen, Jiang Ying Journal of General Surgery for Clinicians    2025, 13 (3): 76-.   Abstract （27）            Knowledge map    Save Objective To analyze the effect of rapid rehabilitation nursing on the psychological state and pain of patients with modified radical mastectomy for breast cancer. Method From November 2022 to December 2024, 80 patients with breast cancer in Jianli People's Hospital were selected and randomly divided into observation group and control group, 40 cases in each group. The control group received routine nursing intervention, while the observation group received rapid rehabilitation nursing. The psychological status, pain degree and upper limb function recovery of the two groups were compared. Result Before intervention, there was no significant difference in self-rating depression scale (SAS), self-rating anxiety scale(SDS) scores, Fugl-Meyer assessment scale upper extremity (FMA-UE) and motricity index upper extremity(MI-UE) scores between the two groups (P ＞ 0.05). After the intervention, the SAS and SDS scores of the two groups were lower than those before the intervention, and the observation group was lower than that of the control group, the difference was significant(P ＜ 0.05), and the FMA-UE and MI-UE scores of the two groups were increased, and the observation group was higher (P＜0.05). The visual analogue scale scores of the observation group were lower than those of the control group at 6h, 12h, 1d and 3d after operation, and the difference was significant (P ＜ 0.05). Conclusion Rapid rehabilitation nursing for patients with breast cancer undergoing modified radical mastectomy can significantly reduce their negative emotions and pain, and improve the recovery of upper limb function. Related Articles | Metrics