Table of Content

01 January 2025, Volume 13 Issue 1

Previous Issue   

The eff ects of single port laparoscopic cholecystectomy, triple port laparoscopic cholecystectomy, and open cholecystectomy on stress response levels and gastrointestinal function in patients with cholecystitis and gallstones

Wan Hong

2025, 13(1):  2. 

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Objective To analyze and compare the eff ects of single port laparoscopic cholecystectomy, triple port laparoscopic cholecystectomy, and open cholecystectomy in patients with cholecystitis and gallstones. Method A total of 93 patients with cholecystitis and gallstones who were treated in Yixing Integrated Traditional Chinese and Western Medicine Hospital from January 2022 to January 2024 were selected and included in the study. They were divided into three groups according to diff erent surgical forms, corresponding to open surgery group (31 cas-es), three port laparoscopic group (31 cases), and single port laparoscopic group (31 cases), and each group was treated with open cholecystectomy, three port laparoscopic cholecystectomy, and single port laparoscopic cholecys-tectomy. The perioperative indicators, stress response indicators, gastrointestinal function, and aesthetic degree were compared among the three groups. Result The surgical time and incision length of the three port endoscopy groupand the single port endoscopy group were lower than those of the open surgery group, and the intraoperative blood loss was lower than that of the open surgery group, with signifi cant diff erences (P ＜ 0.05); The levels of C-reactive protein, cortisol, and norepinephrine in the three port endoscopic group and the single port endoscopic group were all higher than those in the open surgery group, and the single port endoscopic group had signifi cantly higher levels of these three indicators than the three port endoscopic group (P ＜ 0.05); The gastric emptying rate, number of gastric antral contractions, and number of gastric body peristalsis in the three port endoscopic group and the single port endoscopic group were all higher than those in the open surgery group, and the above three indicators were all higher in the single port endoscopic group than in the three port endoscopic group (P ＜ 0.05); The postoperative aesthetic degree of the single hole endoscopic group was better than that of the three hole endoscopic group and the open surgery group (P ＜ 0.05). Conclusion Although small incision cholecystectomy and laparoscopic cholecys-tectomy have similar therapeutic eff ects, both can eff ectively treat cholecystitis with gallstones. However, compared to small incision cholecystectomy, laparoscopic cholecystectomy brings less trauma and better postoperative re-covery. Among them, the advantage of the single hole endoscopic group is more obvious, and not only does it have better postoperative recovery, but it also has higher aesthetic appeal.

Comparison of the clinical eff ect of laparoscopic and open surgery in the treatment of non-traumatic gastric and small intestinal perforation

Wang Yang, Lu Xian

2025, 13(1):  7. 

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Objective To observe and compare the clinical effi cacy of open surgery with laparoscopic surgery in the treatment of non-traumatic perforation of stomach and small intestine. Method The clinical data of patients with upper digestive tract perforation admitted to Kunshan Traditional Chinese Medicine Hospital Affi liate to Nan-jing University of Chinese Medicine from February 2016 to March 2022 were retrospectively analyzed. Among them, 53 cases underwent laparoscopic surgery and 46 cases underwent open surgery. The perioperative indicators of the two groups, such as gender, age, body mass index, operation time, anal exhaust time, length of stay, postop-erative infl ammation, nutritional status and surgery complications were compared and analyzed. Result There was no signifi cant diff erence in preoperative basic data such as age and gender between the two groups (P ＞ 0.05). Compared with the open group, the operation time of the laparoscopic group was shorter [(55.5±21.6) min vs.

(76.1±47.2)min, P ＜ 0.005]. postoperative anal exhaust time was early [(3.4±1.2)d vs. (5.4±1.0)d, P ＜ 0.001], abdominal drainage tube placement time was short [(5.8±1.2)d vs. (7.9±1.7)d, P ＜ 0.001]. the hospital stay was shorter [(9.9±2.3)d vs. (13.4±4.8)d, P ＜ 0.001], and the total cost was lower [(1.58±0.50)ten thousand yuan vs. (2.54±1.58)ten thousand yuan, P ＜ 0.001]. In addition, the laparoscopic group had better infl ammation and nutritional indexes three days after surgery(P ＜ 0.05), and there was no signifi cant diff erence in the incidence of postoperative complications between the two groups (P ＞ 0.05). Conclusion Under the condition of the indications of laparoscopic surgery, laparoscopic surgery has signifi cant clinical eff ect, less surgical trauma, and faster postop-erative recovery, which is worthy of clinical application.

Analysis of risk factors for postoperative pulmonary infection in patients undergoing emergency surgery for upper gastrointestinal perforation

Ruan Haigang, Wang Chengxing

2025, 13(1):  11. 

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Objective To investigate the risk factors for pulmonary infection following emergency surgery for upper gastrointestinal perforation. Method A total of 350 patients diagnosed with upper gastrointestinal per-foration who underwent emergency surgery at our hospital were analyzed. Based on the presence of postoperative pulmonary infection, the patients were divided into an infection group and a non-infection group. Univariate and multivariate logistic regression analyses were conducted to identify the risk factors for pulmonary infection. Result Univariate analysis revealed that the infection group had a higher proportion of patients with a history of smoking (P ＜ 0.001), hypertension (P=0.008), preoperative gastric tube placement (P ＜ 0.001), shock (P ＜ 0.001), dia-betes (P ＜ 0.001) , and reason for perforation (P=0.004)compared to the non-infection group. Multivariate logistic regression analysis indicated that a history of smoking and hypertension are independent risk factors for pulmonary infection following surgery for upper gastrointestinal perforation (P ＜ 0.05). Conclusion A history of smoking and hypertension are signifi cant risk factors for the occurrence of pulmonary infection after emergency surgery for up-per gastrointestinal perforation.

Application of selective portal vein staining combined with hepatic lobe blood flow obstruction in right lobe anatomical hepatectomy

Chen Haimin, Zhu Qingsheng

2025, 13(1):  16. 

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Objective To investigate the application eff ect of hepatic lobe blood fl ow obstruction combined with selective portal vein staining in right lobe anatomical liver resection. Method The research subjects were 82 patients who underwent right lobe anatomical liver resection at Yuebei People’s Hospital from January 2022 to October 2023. They were randomly divided into two groups, an experimental group and a control group, with 41 pa-tients in each group. The experimental group received hepatic lobe blood flow obstruction, while the control group received the Pringle method of fi rst porta hepatis obstruction. Portal vein staining was performed in both groups to compare the therapeutic eff ects. Result There was no signifi cant diff erence in surgical time between the two groups of patients (P ＞ 0.05), but the experimental group had a shorter hospital stay and less intraoperative bleeding than the control group, with signifi cant diff erences (P ＜ 0.05). Before surgery, there was no signifi cant diff erence in liver function indicators between the two groups of patients (P ＞ 0.05); After surgery, the total albumin level in the experimental group was higher than that in the control group, and the total bilirubin and alanine aminotransferase levels were lower than those in the control group, with signifi cant diff erences (P ＜ 0.05). There was no signifi cant diff erence in the incidence of postoperative bile leakage, bleeding, and infection between the two groups of patients (P ＞ 0.05), but the incidence of hepatic vein injury in the experimental group was lower than that in the control group, and the recurrence rate was lower than that in the control group after 6 months of follow-up, with signifi cant diff erences (P ＜ 0.05). Conclusion The combination of hepatic lobe blood flow obstruction and portal vein stain-ing can reduce intraoperative bleeding and lower the incidence of postoperative complications in right lobe anatom-ical liver resection. It is a safe and feasible treatment method.

Comparison of the effi cacy and safety of transcatheter arterial chemoembolization and hepatic artery infusion chemotherapy in the treatment of primary liver cancer patients

Jiang Zheng, Wen Kailin, Zha Huangqi, Guo Zhengjun, Wu Wenjing

2025, 13(1):  21. 

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Objective To compare the application eff ects of transcatheter arterial chemoembolization (TACE) and hepatic artery infusion chemotherapy (HAIC) in the treatment of primary liver cancer patients. Method 80 patients with primary liver cancer admitted to Guangzhou General Hospital of China Life Insurance from January 2023 to January 2024 were selected and randomly divided into two groups, with 40 patients in each group, using a random number table method. The control group was treated with HAIC, while the observation group was treated with TACE. Compare the clinical treatment effi cacy, tumor markers, liver function indicators, and safety between two groups. Result The total eff ective rate of the observation group was 95.00% (38/40), which was higher than that of the control group [80.00%(32/40)], and the diff erence was signifi cant(P ＜ 0.05). Before treatment, there was no signifi cant diff erence in the levels of tumor markers and liver function indicators between the two groups of patients(P ＞ 0.05); After treatment, the serum carcinoembryonic antigen of the observation group patients was (8.17±1.23)μg/L, carbohydrate antigen 125 was (23.45±3.52)U/ml, aspartate aminotransferase was (51.66±5.24)U/L, alanine aminotransferase was (69.36±7.22)U/L, and total bilirubin was (15.79±2.67)μmol/L, which were significantly lower than those of the control group [(9.65±1.14)μg/L, (28.97±3.29)U/ml, (62.70±6.35)U/L, (78.95±9.13)U/L, (19.45±3.06)μmol/L, respectively], and the diff erences were signifi cant (P ＜ 0.05). There was no signifi cant diff erence in the incidence of complications between the two groups of patients (P ＞ 0.05). Conclusion Compared with HAIC, TACE treatment for primary liver cancer can achieve better effi cacy, reduce tumor markers, improve liver function, and has high safety.

Research status of immune cell regulation and therapy in non-alcoholic steatohepatitis

Guo Shiqi, Xing Cheng, Ge Yunpeng, Shi Haowei, Zheng Yangyang, Song Jinghai,

2025, 13(1):  25. 

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With the global prevalence of metabolic diseases increasing year by year, metabolism related non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease. NAFLD disease spectrum included initial liver steatosis, advanced non-alcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular carcinoma (HCC). In NASH stage, lipotoxicity and inflammatory damage of hepatocytes greatly increase the risk of end-stage liver disease. So far, there have been more than 1400 clinical trials for the treatment of Nash worldwide, but no specifi c drugs have been approved with no eff ective treatment for NASH related HCC. Even for emerging immunotherapy, NASH related HCC also showed signifi cant resistance to immunotherapy. The changes of immune microenvironment mediated by innate and adaptive immune cell subsets play an important role in the onset and progression of NASH. Thi s review focuses on the mechanism of a variety of immune cells in NASH and the research status of related immunotherapy, in order to provide reference for understanding the immune microenvironment of NASH and exploring new research directions.

Exploration of the eff ect of total thyroidectomy combined with central and lateral neck lymph node dissection for the treatment of metastatic thyroid cancer

Cui Zhiwei

2025, 13(1):  33. 

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Objective To explore the clinical eff ect of total thyroidectomy combined with central and lateral neck lymph node dissection in the treatment of thyroid cancer. Method Fifty patients with thyroid cancer admitted to Hainan District People’s Hospital in Wuhai City from January 2022 to January 2024 were selected and random-ly divided into two groups, with 25 patients in each group. The control group underwent total thyroidectomy plus central lymph node dissection, while the study group underwent total thyroidectomy plus central and lateral neck lymph node dissection. The treatment eff ects of the two groups were compared. Result There was no signifi cant dif-ference in perioperative indicators and incidence of complications between the study group and the control group (P ＞ 0.05); The postoperative quality of life and recurrence rate of patients in the study group were signifi cantly better than those in the control group, with signifi cant diff erences (P ＜ 0.05). Conclusion Total thyroidectomy combined with lymph node dissection is an eff ective treatment for metastatic thyroid cancer, which can signifi cantly improve the clinical prognosis of patients and reduce the risk of recurrence.

Evaluation of the eff ect of surgical treatment of breast fi broadenoma through areola incision

Sang Kai

2025, 13(1):  38. 

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Objective To explore the clinical eff ect of surgical treatment of breast fi broadenoma through areola incision. Method 70 female patients with breast fi broadenoma admitted to Taizhou People’s Hospital from May 2022 to April 2024 were selected and randomly divided into a study group and a control group, with 35 cases in each group. The control group underwent traditional breast fi broadenoma resection, while the study group under-went areola incision breast fi broadenoma resection. The perioperative conditions, postoperative incision recovery, quality of life, as well as complications and recurrence were compared between the two groups of patients. Result The intraoperative blood loss and length of hospital stay in the study group were less than those in the control group, and the incision length was shorter than that in the control group; And the total eff ective rate of the study group patients was 97.14%, signifi cantly higher than the control group (82.86%), with signifi cant diff erences (P ＜ 0.05). The Vancouver Scar Scale score and European Organization for Research and Treatment Quality of Life Questionnaire score of patients in the study group were signifi cantly lower than those in the control group at 1 and 3 months after surgery. The incidence of complications and recurrence rate of patients in the study group were 2.86% (1/35) and 0, respectively, which were signifi cantly lower than those in the control group [17.14% (6/35) and 11.43% (4/35), respectively], and the diff erences were signifi cant (P ＜ 0.05). Conclusion The application of the areola incision for breast fi broadenoma resection has a signifi cant therapeutic eff ect, which is benefi cial for reducing damage, accelerating recovery, improving aesthetics, and enhancing patients’ quality of life.

The value of ultrasound guided minimally invasive breast biopsy in excision breast cancer

Wu Hanrong, Liu Sanying

2025, 13(1):  42. 

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Objective To investigate the value of ultrasound guided minimally invasive rotary mastectomy in screening breast cancer. Method A retrospective analysis was conducted on the clinical data of 238 patients who underwent breast rotational resection surgery at Changyang County Maternal and Child Health Hospital from October 2021 to June 2023. Summarize the proportion of patients undergoing ultrasound-guided minimally invasive rotational mastectomy. Result Among the 238 patients who underwent breast rotational resection surgery, 225 (94.54%) were diagnosed with benign lesions, including 146 cases (61.34%) of breast adenosis with adenoma formation (including breast adenosis), 68 cases (28.57%) of adenofi broma, 5 cases (2.10%) of intraductal

papilloma, and 6 cases (2.52%) of other benign lesions (active epithelial hyperplasia, with or without atypical hyperplasia); Nine cases (3.78%) were diagnosed with malignant lesions, including one case (0.42%) of ductal carcinoma in situ and eight cases (3.36%) of invasive ductal carcinoma; Two cases (0.84%) of borderline lobular tumors; 2 cases (0.84%) of precancerous lesions (atypical hyperplasia of ductal epithelium). 152 cases of BI-RADS type 3 nodules, 3 of which were diagnosed as breast cancer, with a malignant rate of 1.97%; There were 72 cases of BI-RADS 4a nodules, 6 of which were breast cancer, with a malignant rate of 8.33%; There were 14 cases of BI-RADS type 2 nodules, and no case of breast cancer was found. Conclusion Ultrasound guided minimally invasive rotary mastectomy has significant advantages as a biopsy method in the diagnosis of benign breast lesions and breast cancer due to its precise positioning, minimally invasive and safety, especially for those patients with BI-RADS classifi cation of grade 3 and 4a and high risk factors of breast cancer, especially those who are not suitable for regular observation.

Comparison of the eff ectiveness, safety, and recurrence of laparoscopic repair and open repair in the treatment of acute gastric perforation

Zhang Kui, Chen Jinggen

2025, 13(1):  46. 

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Objective To compare the therapeutic eff ects of laparoscopic repair and open repair for acute gas-tric perforation. Method 100 patients with acute gastric perforation admitted to Yunxi County People’s Hospital in Shiyan City from January 2021 to December 2023 were selected and randomly divided into two groups of 50 each using a random number table method. The control group underwent open abdominal repair surgery, while the obser-vation group underwent laparoscopic repair surgery. The clinical eff ects of the two groups were compared. Result The incision length of the observation group patients was shorter than that of the control group, the intraoperative blood loss was less than that of the control group, and the operation time, bed getting time, bowel sound recovery time, exhaust time, and hospitalization time were all shorter than those of the control group, with signifi cant dif-ferences (P ＜ 0.001). Before surgery, there was no signifi cant diff erence in the levels of gastrointestinal hormones and infl ammatory factors between the two groups of patients (P ＞ 0.05); After surgery, the levels of vasoactive intestinal peptide, gastrin, and motilin in the observation group were higher than those in the control group, while the levels of interleukin-6, tumor necrosis factor - α, and C-reactive protein were lower than those in the control group, with signifi cant diff erences (P ＜ 0.001). The total incidence of complications in the observation group was 2.00% (1/50), and the recurrence rate was 0, both lower than those in the control group [20.00% (10/50), 44.00% (6/50), respectively], with signifi cant diff erences (P ＜ 0.05). Conclusion Laparoscopic repair and open repair can both improve the condition of patients with acute gastric perforation to a certain extent. However, laparoscopic re-pair can reduce the trauma to the patient’s body, help alleviate the body’s infl ammatory response and lower the incidence of postoperative complications and recurrence.

Clinical observation of remifentanil tosylate used for anesthesia in elderly patients undergoing endoscopic retrograde cholangiopancreatography

Zhang Miaomiao

2025, 13(1):  50. 

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Objective To investigate the anesthetic eff ect of remifentanil tosylate on elderly patients under- going endoscopic retrograde cholangiopancreatography. Method Eighty elderly patients undergoing endoscopic retrograde cholangiopancreatography admitted to Shuyang Mercy Hospital in Suqian City from January 2021 to June 2024 were randomly divided into two groups using a random number table. The control group (n=40) received combined anesthesia with propofol and sufentanil, while the observation group (n=40) received combined anesthe-sia with remifentanil and sufentanil. Compare surgical related indicators, hemodynamic parameters at diff erent time points, levels of infl ammatory factors before and after surgery, pain scores, quality of life scores, and incidence of adverse events between two groups of patients. Result There was no signifi cant diff erence in surgical time, intra-operative blood loss, and complete stone clearance rate between the two groups of patients (P ＞ 0.05), but the observation group had fewer body movements during surgery and shorter postoperative recovery time than the control group, with signifi cant diff erences (P ＜ 0.001). There was no signifi cant diff erence (P ＞ 0.05) in heart rate, mean arterial pressure, and blood oxygen saturation between the two groups of patients before anesthesia and when awake after surgery. At the time of insertion and 10 minutes after insertion, the heart rate, mean arterial pressure, and blood oxygen saturation of the observation group were signifi cantly higher than those of the control group (P ＜ 0.05). Before surgery, there was no signifi cant diff erence in the levels of infl ammatory factors, pain scores, and quality of life scores between the two groups of patients (P ＞ 0.05). After surgery, the levels of tumor necrosis factor-α and interleukin-6 in the observation group were lower than those in the control group, the pain score was lower than that in the control group, and the quality of life score was higher than that in the control group, with signifi cant diff er-ences (P ＜ 0.001). The incidence of adverse reactions in the observation group was signifi cantly lower than that in

the control group (5.00% vs. 25.00%; χ2=6.275, P=0.012). Conclusion The use of remifentanil tosylate anesthesia in elderly patients undergoing endoscopic retrograde cholangiopancreatography can improve anesthesia eff ective-ness, reduce postoperative pain, improve quality of life, and increase safety.

Application and eff ect analysis of laparoscopic technology in surgical treatment of gastrointestinal malignant tumor patients

Jin Zhan, Zhou Ming

2025, 13(1):  55. 

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Objective To explore the application and eff ectiveness of laparoscopic technique in the surgical treatment of gastrointestinal malignant tumors. Method 70 patients with gastrointestinal malignant tumors who un-derwent surgical treatment at Suining County People’s Hospital in Xuzhou City from November 2022 to Novem-ber 2024 were selected and divided into an experimental group (35 cases, using laparoscopic gastrointestinal malig-nant tumor resection surgery) and a control group (35 cases, open abdominal surgery) according to diff erent surgical methods. The surgical treatment eff ect and postoperative recovery of the two groups of patients were observed. Result The surgical treatment time of the experimental group patients was longer than that of the control group, and the intraoperative blood loss was less than that of the control group. The postoperative exhaust time, liquid and solid food intake time, bed rest time, hospitalization time, analgesic use time, and indwelling catheterization time were all shorter than those of the control group, and the diff erences were signifi cant (P ＜ 0.05). Before treatment, there was no signifi cant diff erence in visual analogue scale(VAS) scores between the two groups of patients. After treatment, the VAS scores of the experimental group were lower than those of the control group. The incidence of complications in the experimental group was 5.71% (2/35), which was lower than that of the control group [22.86% (8/35)], and the diff erences were signifi cant (P ＜ 0.05). Before treatment, there was no signifi cant diff erence in sleep quality between the two groups of patients (P ＞ 0.05). After treatment, the sleep quality of the experimen-tal group was better than that of the control group, and the diff erence was signifi cant (P ＜ 0.05). Conclusion The auxiliary application of laparoscopic technology in the surgical treatment of gastrointestinal malignant tumors can reduce the degree of damage to the patient’s body, promote postoperative recovery, and improve sleep quality.

The diagnostic eff ect of gastrointestinal ultrasound contrast agents in ultrasound diagnosis of middle and lower common bile duct lesions

Li Hong, Luo Haoyan, Chen Mengnan

2025, 13(1):  60. 

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Objective To explore the diagnostic eff ect of gastrointestinal ultrasound contrast agents in the ultra-sound diagnosis of middle and lower common bile duct lesions. Method A retrospective analysis was conducted on the clinical data of 80 patients with suspected middle and lower common bile duct lesions admitted to Jilin Chemi-cal Industry Hospital from January 2021 to January 2024. All patients received simple ultrasound diagnosis and gas-trointestinal ultrasound assisted ultrasound diagnosis. The clinical comprehensive examination results and patholog-ical diagnosis results were used as the gold standard to compare the diagnostic results of diff erent methods. Result Among the 80 suspected patients with lesions in the middle and lower segments of the common bile duct, based on clinical comprehensive examination results and pathological diagnosis as the gold standard, there were 67 cases of lesions in the middle and lower segments of the common bile duct, including 40 cases of tumors in the middle and lower segments of the common bile duct, 19 cases of stones in the middle and lower segments of the common bile

duct, and 8 cases of tumors in the duodenal ampulla; 6 cases of intrahepatic bile duct stones; 3 cases of pancreatitis; 1 case of cholangiocarcinoma; Three cases of intrahepatic and extrahepatic bile duct dilation. Gastrointestinal ul-trasound contrast agents have a higher positive detection rate, sensitivity, accuracy, and disease diagnosis detection rate compared to simple ultrasound diagnosis, with signifi cant diff erences (P ＜ 0.05). Conclusion In the ultrasound diagnosis of middle and lower common bile duct lesions, the use of gastrointestinal ultrasound contrast agents can improve clinical diagnostic accuracy, clarify disease types, and provide accurate references for clinical practice.




Study on the effi cacy of endoscopic mucosal dissection in the treatment of early colorectal cancer and precancerous lesions

Wang Hongqi

2025, 13(1):  64. 

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Objective To investigate the clinical effi cacy and safety of endoscopic mucosal dissection in the treatment of early colorectal cancer and precancerous lesions. Method Sixty patients with early colorectal cancer and precancerous lesions admitted to Nanjing Anal Tai Traditional Chinese Medicine Hospital from January 2022 to December 2023 were randomly divided into two groups using a random number table. The control group (n=30) underwent endoscopic mucosal resection, while the observation group (n=30) underwent endoscopic submucosal dissection. The perioperative indicators, levels of infl ammatory factors, stress response indicators, and biochemical indicators before and after surgery were compared between the two groups of patients. Result The surgical time, re-covery time, analgesia time, hospitalization time, and incision length of the observation group were all shorter than those of the control group, and the intraoperative blood loss was less than that of the control group, with signifi cant

differences (P ＜ 0.05). Before surgery, there were no signifi cant diff erences in the levels of infl ammatory factors, stress response indicators, and biochemical indicators between the two groups of patients (P ＞ 0.05). After surgery, the levels of infl ammatory factors and stress response indicators in the observation group were signifi cantly low-er than those in the control group (P ＜ 0.05); After surgery, the levels of motilin, somatostatin, and vascular cell adhesion molecule-1 in the observation group were signifi cantly lower than those in the control group (P ＜ 0.05). Conclusion Early stage colon cancer and precancerous lesions can be treated with submucosal dissection under di-gestive endoscopy to improve their infl ammatory factors and stress response.

Application of three-dimensional mesh combined with platelet rich gel in laparoscopic inguinal hernia repair

Xu Wenqiang

2025, 13(1):  69. 

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Objective To investigate the eff ect of three-dimensional mesh combined with platelet rich gel in laparoscopic transabdominal preperitoneal hernia repair. Method Ninety patients with inguinal hernia admitted to Qingyang Hospital in Jiangyin City from January 2021 to December 2023 were selected and randomly divided into a control group and a study group using a random number table, with 45 patients in each group. The control group used ordinary patch combined with medical glue, and the research group used three-dimensional patch combined with platelet rich gel. Compare two groups of clinical indicators, pain levels, infl ammatory cytokine levels, inci-dence of complications, recurrence, and clinical effi cacy. Result The surgical time, fi rst mobilization time, hospi-talization time, and incision pain time of the study group were shorter than those of the control group, and the intra-operative blood loss was less than that of the control group. The postoperative pain score was lower than that of thecontrol group, and the diff erences were signifi cant (P ＜ 0.05). Before treatment, there was no signifi cant diff erence in the levels of interleukin-6, tumor necrosis factor alpha, and C-reactive protein between the two groups of patients (P ＞ 0.05). After treatment, the levels of interleukin-6, tumor necrosis factor alpha, and C-reactive protein in the study group were signifi cantly higher than those in the control group (P ＜ 0.05). The total eff ective rate of the re-search group was higher than that of the control group, and the postoperative recurrence rate and total incidence of complications were lower than those of the control group, with signifi cant diff erences (P ＜ 0.05). Conclusion The application of three-dimensional patch combined with platelet rich gel in TAPP can reduce the recurrence rate, re-duce complications and improve the quality of life of patients.

Comparison of the eff ects of traditional external stripping and internal ligation surgery and stapled hemorrhoidectomy for the treatment of hemorrhoids patients

Yu Desheng, Xin Cuiyan, Zhang Huanchang, Chen Jiankai

2025, 13(1):  74. 

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Objective To evaluate the effi cacy of traditional external stripping and internal ligation surgery, as well as procedure for prolapse and hemorrhoids (PPH) with a stapler, in patients with hemorrhoids. Method A total of 110 hemorrhoids patients admitted to Qingxin District People’s Hospital in Qingyuan City from January 2015 to December 2023 were included in the study. They were randomly divided into a control group (55 cases, treated with traditional surgical therapy) and an observation group (55 cases, treated with PPH hemorrhoid surgery) using a random number table. The clinical effi cacy rate, perioperative indicators, and incidence of complications between the groups were evaluated. Result One month after surgery, one patient in the control group was eff ective and 52 patients were cured; One eff ective case was observed in the observation group, and 54 cases were cured. The eff ec-tive rates of both groups of patients were 100%, with no signifi cant diff erence (χ2=0.000, P=1.000). Compared with the control group, the observation group had less intraoperative bleeding, shorter operation time and hospitalization time, and lower incidence of complications, with signifi cant diff erences (P ＜ 0.05). Conclusion Both traditional external stripping and internal ligation surgery and PPH can eff ectively treat hemorrhoid patients, but the latter can improve perioperative indicators and reduce the incidence of complications.

Comparison of the application eff ects of laparoscopic transabdominal preperitoneal prosthesis and open tension-free anterior peritoneal hernia repair

Zhou Kunlin

2025, 13(1):  78. 

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Objective To investigate the efficacy of laparoscopic transabdominal preperitoneal prosthesis (TAPP) and open pre peritoneal tension-free hernia repair in the treatment of inguinal hernia. Method 80 patients with inguinal hernia admitted to the Second People’s Hospital of Xiangcheng District in Suzhou City from January 2022 to October 2024 were selected for the study. They were divided into two groups of 40 patients each ac-cording to the surgical method. The control group received open peritoneal tension-free hernia repair surgery, while the observation group received laparoscopic TAPP treatment. The perioperative infl ammatory response indicators, postoperative recovery, and incidence of complications were compared between the two groups of patients. Result On postoperative day 1, serum C-reactive protein, procalcitonin, and neutrophil percentage signifi cantly increased in both groups, while the observation group was signifi cantly lower than the control group (P ＜ 0.01). The recov-ery time of bowel sounds, anal exhaust time, spontaneous activity time, and hospitalization time of the observation group patients were shorter than those of the control group, and the pain level at 12 hours, 24 hours, and 48 hours after surgery was milder than that of the control group, with signifi cant diff erences (P ＜ 0.001). The incidence of complications in the observation group (5.00%) was signifi cantly lower than that in the control group (22.50%) (χ2=5.165, P=0.023). Conclusion Compared with open retroperitoneal tension-free hernia repair, laparoscopic TAPP has more advantages in treating inguinal hernia, promoting rapid postoperative recovery, reducing infl amma-tion and early pain, and minimizing postoperative complications.

Application eff ect of cluster nursing in preventing hypoglycemia in patients after high-frequency electrocautery of gastrointestinal polyps under endoscopy

Chen Xin, Zhang Jie

2025, 13(1):  85. 

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Objective To analyze the application eff ect of bundle nursing in preventing hypoglycemia in pa-tients undergoing high-frequency electrocautery of gastrointestinal polyps under endoscopy. Method A total of 178 patients who underwent endoscopic high-frequency resection of gastrointestinal polyps at Tongji Hospital affi liated to Tongji Medical College of Huazhong University of Science and Technology from May 2023 to October 2023 were selected and randomly divided into a control group and an observation group, with 89 patients in each group. The incidence of postoperative hypoglycemia and nursing satisfaction were analyzed in both groups using a random number table method. Result The incidence of postoperative hypoglycemia in the observation group was 3.4%, signifi cantly lower than the 23.6% incidence in the control group. The nursing satisfaction rate was 93.2%, higher than the 76.4% satisfaction rate in the control group, and the diff erences were signifi cant (P ＜ 0.05). Conclusion Cluster nursing can reduce the incidence of hypoglycemia after high-frequency resection of gastrointestinal polyps under endoscopy and improve patients’ nursing satisfaction.

Application of individual centered perioperative nursing in postoperative patients with gallstones

Li Juanjuan

2025, 13(1):  89. 

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Objective To explore the application eff ect of individual centered perioperative nursing in post-operative patients with gallstones. Method 80 patients who underwent gallstones surgery at the Second People’s Hospital of Hefei from October 2022 to July 2024 were selected as the study subjects. They were randomly divided into a control group and an observation group, with 40 patients in each group, using a random number table method. The control group received routine care, while the observation group received individual centered perioperative care. The surgical indicators, postoperative numerical rating scale(NRS) scores, and incidence of complications were compared between the two groups of patients. Result The observation group had shorter exhaust time, fi rst time getting out of bed, and hospitalization time compared to the control group. The hospitalization cost was lower

than that of the control group, and the scores of the digital grading system at 24 hours and 72 hours after surgery were lower than those of the control group, with signifi cant diff erences (P ＜ 0.05). The incidence of postoperative complications in the observation group was 5.00%, signifi cantly lower than that in the control group (22.50%), and the diff erence was signifi cant (P ＜ 0.05). Conclusion The clinical application of individual centered perioperative nursing has shown good results, which can fully improve patient perioperative related indicators and alleviate pa-tient pain.

Research on the application value of operating room nursing based on the concept of accelerated rehabilitation surgery in patients undergoing laparoscopic cholecystectomy

Sun Xiahui, Zhu Mingyue

2025, 13(1):  93. 

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Objective To analyze the application value of operating room nursing based on the concept of accelerated rehabilitation surgery in patients undergoing laparoscopic cholecystectomy. Method 42 patients who underwent laparoscopic cholecystectomy at Zhenjiang 359 Hospital from January 2022 to March 2023 were se-lected and randomly divided into an observation group and a control group, with 21 patients in each group, using a random number table method. The control group received routine nursing in the operating room, while the obser-vation group received operating room nursing based on the concept of accelerated rehabilitation surgery. Compare the vital signs, surgical indicators, incidence of complications, and nursing satisfaction between two groups. Result Before surgery, there was no signifi cant diff erence in heart rate, systolic blood pressure, and diastolic blood pressure between the two groups of patients (P ＞ 0.05). After surgery, the heart rate of the observation group was higher than that of the control group, and both systolic and diastolic blood pressure were lower than those of the control group, with signifi cant diff erences (P ＜ 0.05). The observation group had shorter surgical time, wakefulness time, mobilization time, exhaust time, fi rst meal time, and hospitalization time compared to the control group, and the to-tal incidence of complications was lower than that of the control group, with signifi cant diff erences (P ＜ 0.05). The nursing scores of the observation group were signifi cantly higher than those of the control group (P ＜ 0.05). Conclusion Implementing operating room nursing based on the concept of accelerated rehabilitation surgery for patients undergoing laparoscopic cholecystectomy can help stabilize patients’ vital signs, improve surgical indicators, and reduce complications.

The impact of bundle nursing based on insulation intervention on patients undergoing laparoscopic cholecystectomy

Zuo Meijuan, Wu Min

2025, 13(1):  98. 

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Objective To analyze the eff ect of bundle nursing based on insulation intervention on perioperative recovery of patients undergoing laparoscopic cholecystectomy (LC). Method 104 patients who received LC at Li-anshui County People’s Hospital from July 2022 to July 2024 were selected and randomly divided into an obser-vation group (bundle nursing based on insulation intervention) and a control group (conventional nursing), with 52 patients in each group, using a random number table method. Monitor the temperature changes of two groups of pa-tients before surgery, 30 minutes during surgery, 60 minutes during surgery, 60 minutes after surgery, and compare the coagulation function indicators [fi brinogen (FIB), thrombin time (TT), activated partial thromboplastin time (APTT)] of the two groups of patients before surgery and 60 minutes after surgery. Result The observation group had signifi cantly higher body temperatures at 30 minutes, 60 minutes, and after surgery compared to the control group (P ＜ 0.05). There was no signifi cant diff erence in FIB, TT, and APTT between the two groups of patients before and 60 minutes after surgery (P ＞ 0.05). At 60 minutes after surgery, the FIB level in the observation group was higher than that in the control group, while TT and APTT were shorter than those in the control group (P＜0.05). Conclusion Bundle nursing based on insulation intervention can signifi cantly maintain stable intraoperative body temperature and coagulation function indicators in LC patients.

The eff ect of functional dressings combined with specialized wound and stoma nursing on postoperative wound recovery in patients with anal and rectal diseases

Huang Min, Wang Enhui, Xu Meiying, Ouyang Ling, Zeng Fanying, Jiang Jingxia

2025, 13(1):  102. 

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Objective To analyze the eff ect of functional dressings combined with specialized wound stoma nursing on postoperative wound recovery in patients with colorectal diseases. Method 120 patients with colorectal diseases admitted to Longhua District People’s Hospital in Shenzhen from May 2023 to June 2024 were select-ed and randomly divided into a study group (functional dressing combined with wound stoma specialty nursing) and a control group (conventional nursing) using a random number table method, with 60 patients in each group. The nursing effects of the two groups were compared. Result Compared with the control group, the patients in the study group had a shorter wound healing time, fewer dressing changes and debridement hospitalizations, and a higher number of wound pathogen seroconversion after 15 days of treatment, with significant differences (P ＜ 0.05). Before nursing, there was no signifi cant diff erence in wound area and pain score between the two groups of patients. After nursing, compared with the control group, the study group had a smaller wound area, lower gran-ulation growth score and pain score, and the diff erences were signifi cant (P ＜ 0.05). Before nursing, there was no signifi cant diff erence in white blood cell count, interleukin-6, and C-reactive protein levels between the two groups of patients (P ＞ 0.05). After nursing, the white blood cell count, interleukin-6, and C-reactive protein of the study group patients were lower than those of the control group (P ＜ 0.05). Conclusion The combination of functional dressings and specialized wound and stoma care can accelerate the postoperative wound recovery speed and reduce the pain burden in patients with colorectal diseases.

Application of 5A nursing mode in rapid rehabilitation of a patient with colon cancer and coronary atherosclerotic heart disease

Ouyang Ting, Jia Haina

2025, 13(1):  107. 

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Objective To summarize the clinical effect of 5A nursing mode in the rapid rehabilitation of patients with colon cancer and coronary atherosclerotic heart disease. Method One case of colon cancer complicated with coronary heart disease from June 2024 was selected as the research object, and a 5A nursing model was implemented during the perioperative period. The eff ects of this nursing model on the patient's cardiac function changes, pain perception, nutritional status, psychological status, and venous thrombosis formation were observed. Result The 5A nursing model was implemented for the patient during the perioperative period, and the patient's rehabilitation eff ect was good. The heart function was stable, the pain was signifi cantly reduced, the urinary frequency symptoms were relieved, the body's nutritional status was good, the surgical wound healing was good, and there were no symptoms of anxiety or depression, and no lower limb venous thrombosis occurred. Conclusion The 5A nursing model, using scientifi c methods to evaluate the actual situation of patients and develop and implement personalized nursing intervention plans, can promote rapid postoperative recovery of patients' physical function, stabilize cardiac function, reduce disease pain, improve patients' body mass and quality of life, correct patients' adverse psychological states, and prevent complications.