Abstract:

Objective To investigate the eff ect of three-dimensional mesh combined with platelet rich gel in laparoscopic transabdominal preperitoneal hernia repair. Method Ninety patients with inguinal hernia admitted to Qingyang Hospital in Jiangyin City from January 2021 to December 2023 were selected and randomly divided into a control group and a study group using a random number table, with 45 patients in each group. The control group used ordinary patch combined with medical glue, and the research group used three-dimensional patch combined with platelet rich gel. Compare two groups of clinical indicators, pain levels, infl ammatory cytokine levels, inci-dence of complications, recurrence, and clinical effi cacy. Result The surgical time, fi rst mobilization time, hospi-talization time, and incision pain time of the study group were shorter than those of the control group, and the intra-operative blood loss was less than that of the control group. The postoperative pain score was lower than that of thecontrol group, and the diff erences were signifi cant (P ＜ 0.05). Before treatment, there was no signifi cant diff erence in the levels of interleukin-6, tumor necrosis factor alpha, and C-reactive protein between the two groups of patients (P ＞ 0.05). After treatment, the levels of interleukin-6, tumor necrosis factor alpha, and C-reactive protein in the study group were signifi cantly higher than those in the control group (P ＜ 0.05). The total eff ective rate of the re-search group was higher than that of the control group, and the postoperative recurrence rate and total incidence of complications were lower than those of the control group, with signifi cant diff erences (P ＜ 0.05). Conclusion The application of three-dimensional patch combined with platelet rich gel in TAPP can reduce the recurrence rate, re-duce complications and improve the quality of life of patients.

Key words: Transabdominal preperitoneal prosthesis, Three-dimensional patch, Platelet rich gel, Pain,