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Analysis of the therapeutic effect of intersphincteric incision and thread hanging surgery for high complex anal fistula Xie Feng Journal of General Surgery for Clinicians    2025, 13 (2): 88-.   Abstract （27）            Knowledge map    Save Objective To observe the clinical effect of the application of intersphincteric incision and thread drawing surgery for the treatment of high complex anal fistula. Method A total of 90 patients with high complexity anal fistula admitted to Rongxian Integrated Traditional Chinese and Western Medicine Orthopedic Hospital in Yulin City from June 2021 to June 2024 were selected and randomly divided into an observation group of 45 cases and a control group of 45 cases using a random number table. The observation group was treated with intersphincteric incision virtual suture technique, while the control group was treated with conventional incision suture technique. The postoperative anal pain, wound healing time, and efficacy were compared between the two groups of patients. Result The clinical efficacy of the observation group was higher than that of the control group (100.0% vs. 91.1%), and the difference was significant (P ＜ 0.01). The wound healing time and hospitalization time of the observation group were significantly shorter than those of the control group (P ＜ 0.001). Before surgery, there was no significant difference in incontinence scores between the two groups of patients compared to the control group (P ＞ 0.05); At 3 and 6 months after surgery, the incontinence scores of the observation group were significantly lower than those of the control group (P ＜ 0.05). On postoperative day 1 and 2, the visual analogue scale(VAS) scores of the observation group were significantly lower than those of the control group (P ＜ 0.01), but there was no significant difference in VAS scores between the two groups on postoperative day 7 and 10 (P ＞ 0.05). The incidence of postoperative complications in the observation group was 2.2%, with no patient recurrence. The incidence of complications and recurrence in the observation group were lower than those in the control group, and the differences were significant (P ＜ 0.01). Conclusion The surgical plan of intersphincteric incision with virtual hanging line can reduce the hospitalization period of patients, alleviate their pain, and achieve good short-term and long-term therapeutic effects. Related Articles | Metrics

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Construction of a nomogram prediction model for bleeding risk of colorectal adenomatous polyps after endoscopic mucosal resection Ou Yongding, Wang Peng, Zhang Jiaji Journal of General Surgery for Clinicians    2025, 13 (2): 2-.   Abstract （43）            Knowledge map    Save Objective To analyze the risk factors of hemorrhage after endoscopic mucosal resection (EMR) for adenomatous polyps of the large intestine, and to construct a nomogram model of postoperative hemorrhage for adenomatous polyps of the large intestine. Method A total of 300 patients with colorectal adenomatous polyps treated with EMR from January to December 2023 were selected as the modeling group, and 150 patients with colorectal adenomatous polyps treated with EMR from January to June 2024 were selected as the verification group. The patients in the modeling group were divided into bleeding group and non-bleeding group according to whether they experienced postoperative bleeding. Logistic regression analysis was used to screen the risk factors of postoperative bleeding for adenomatous polyps of the large intestine, and R language was used to establish a nomogram model for predicting postoperative bleeding for adenomatous polyps of the large intestine, and finally the model fit and prediction efficiency were evaluated. Result Among the 300 patients, 31 patients had hemorrhage, the incidence of hemorrhage was 10.33%. Clinical data such as smoking history, drinking history, comorbidities, educational level, place of residence, marital status, body mass index, polyp site, number of removed polyps, whether there were tilts and whether there were smooth polyps were compared between the bleeding group and the non-bleeding group , have no significant difference(P ＞ 0.05), while clinical data such as age, sex, polyp size, and whether there were lobed polyps were compared, have a significant difference(P ＜ 0.05). Logistic regression analysis showed that age, sex, polyp size and lobulation were all risk factors for hemorrhage after EMR operation(P ＜ 0.05). The model consistency index (C-index) was 0.851 (95%CI: 0.818-0.884). H-L test showed that the model fit well (χ2=5.365, P=0.305). Receiver operator characteristic curve results showed that the area under the curve value of the nomogram model of hemorrhage after EMR was 0.825. The predicted value of correction curve is close to the actual value. When the prediction threshold probability ranged from 6% to 87%, the net benefit value of nomogram in predicting bleeding after EMR for colorectal adenomatous polyps was higher. Conclusion The nomogram of bleeding risk after endoscopic mucosal resection of adenomatous polyps in the large intestine established in this study is conducive to early clinical identification of high-risk groups for postoperative bleeding, and the nomogram risk prediction model established in this study has guiding significance for medical personnel to make postoperative bleeding prevention and treatment plans. Related Articles | Metrics

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The effect of ceftriaxone combined with metronidazole in the perioperative anti infective treatment of acute suppurative appendicitis Qin Jia, He Qingshi Journal of General Surgery for Clinicians    2025, 13 (2): 93-.   Abstract （34）            Knowledge map    Save Objective To observe the effect of using ceftriaxone combined with metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period. Method A retrospective analysis was conducted on the clinical data of 80 patients with acute suppurative appendicitis who underwent routine postoperative anti-infective treatment (tranexamic acid+metronidazole) at Guilin Integrated Traditional Chinese and Western Medicine Hospital from May 2023 to May 2024 (control group). The clinical data of 80 patients with acute suppurative appendicitis who underwent postoperative anti-infective treatment with ceftriaxone+metronidazole (observation group) were also reviewed during the same period. Statistics were conducted on the incidence of adverse reactions, levels of inflammatory factors before and after 5d of treatment, body temperature, and length of hospital stay for two groups. Result On the day of surgery, there was no significant difference in body temperature levels between the two groups of patients (P ＞ 0.05). On postoperative day 1, 3, and 5, the temperature levels of patients in the observation group were lower than those in the control group, and the hospitalization time was shorter than that in the control group, with significant differences (P ＜ 0.001). Before treatment, there was no significant difference in the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 between the two groups of patients (P ＞ 0.05). After treatment, the levels of inflammatory factors in both groups of patients improved compared to before treatment, and the levels of C-reactive protein, tumor necrosis factor alpha, and interleukin-6 in the observation group were significantly lower than those in the control group (P ＜ 0.01). The incidence of postoperative adverse reactions in the observation group was lower than that in the control group (3.75% vs. 12.50%), and the difference was significant (P ＜ 0.05). Conclusion The combination of ceftriaxone and metronidazole for anti-infective treatment of patients with acute suppurative appendicitis during the perioperative period can reduce the risk of postoperative adverse reactions, lower levels of inflammatory factors, and shorten hospital stay. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2025, 13 (2): 146-.   Abstract （50）            Knowledge map    Save Related Articles | Metrics

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Clinical value of ultrasound real-time monitoring of early complications after appendectomy Mo Fanhua, Su Ming Journal of General Surgery for Clinicians    2025, 13 (3): 55-.   Abstract （27）            Knowledge map    Save Objective To investigate the value of ultrasound real-time monitoring in early complications after appendectomy. Method The clinical and ultrasonic data of 60 patients with complications after appendectomy in Guilin People's Hospital from January 2023 to December 2024 were retrospectively analyzed. The sonographic characteristics of various complications were recorded and summarized. Result Among the 60 patients with complications after appendectomy, there were 16 cases of ascites, 12 cases of abdominal abscess, 23 cases of incision infection, 6 cases of appendicitis stump, and 3 cases of intestinal obstruction. The diagnosis was verified by the results of operation, puncture or clinical follow-up. The ultrasonic characteristics of ascites were clear-cut anechoic or hypoechoic areas, which were mostly banded or irregular flakes; The ultrasonic characteristics of abdominal abscess were mixed echo masses with irregular boundaries, uneven internal echo, flocculent, reticular or cord like strong echo, some of which were combined with liquid-liquid plane or bubble like strong echo and accompanied by rear "comet tail sign" sound shadow; The ultrasonic features of incision infection were thickened and disordered echo of subcutaneous tissue, blurred hierarchical structure, and patchy or irregular hypoechoic areas were seen locally; The ultrasonic characteristics of appendicitis stump were as follows: a cord like blind end structure appeared in the area adjacent to the root of the cecum, the diameter was thickened, the average transverse diameter was 8.4mm (range 7.2 ～ 10.1mm), low to medium echo, uneven internal echo, and spot or strip hyperechoic in the lumen could be seen; The ultrasonic characteristics of intestinal obstruction were typical intestinal dilatation and fluid gas accumulation. Conclusion Ultrasound has important value in the identification of early complications after appendectomy. It can detect abnormal changes in time through dynamic and noninvasive ways, and has practical significance in judging the nature of lesions, evaluating inflammatory activities and guiding clinical intervention. Related Articles | Metrics

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Diagnostic value of erythrocyte distribution width and neuronal enolase in colon cancer Zhou Bo, Su Hongde, Zheng Guangtao, Zhang Junxiang, Zhang Shengfei, Zhao Chuankui Journal of General Surgery for Clinicians    2025, 13 (3): 18-.   Abstract （22）            Knowledge map    Save Objective To explore the diagnostic value of red blood cell distribution width (RDW) and serum neuron specific enolase (NSE) in colon malignant tumors. Method 154 cases of patients with a clear clinical diagnosis of colon cancer (colon cancer group) and 150 cases of healthy people (control group) were selected from The Fifth Affiliated Hospital of Xinjiang Medical University from 2018 January to 2021 January, and the blood routine indexes of the two groups were compared, including red blood cell (RBC), platelet (PLT), lymphocyte ratio (LY%), RDW and tumor We compared the levels of carcinoembryonic antigen (CEA), carbohydrate antigen 125 (CA-125), carbohydrate antigen 125 (CA-199), and NSE in colon cancer patients with diff erent clinical data. RDW and NSE levels in colon cancer patients with diff erent clinical data. The diagnostic value of RDW, NSE, CEA and CA19-9 for colon cancer was analyzed by applying receiver operating characteristic (ROC) curve. Result RBC, LY%, RDW in blood routine, NSE, CEA, CA125, CA19-9 in tumor markers were statistically significant compared with the control group, and there was a significant correlation between the positive expression of serum RDW and the pathological stage of the tumor and whether lymph node metastasis had occurred, and it was concluded that RDW, NSE and its combination with CEA and CA19-9 had high diagnostic value in colon cancer by ROC curve. The ROC curve showed that RDW, NSE and their combination with CEA and CA19-9 had high diagnostic value for colon cancer. Conclusion Elevated levels of RDW and NSE may have a close relationship with the development of colon cancer, and both of them may become an important indicator for the early diagnosis and judgment of colon cancer. Related Articles | Metrics

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Exploration of the value of pain care intervention in improving postoperative quality of life for patients with gallstones Gu Yue Journal of General Surgery for Clinicians    2025, 13 (2): 106-.   Abstract （33）            Knowledge map    Save Objective To explore the effect of pain nursing intervention on postoperative patients with gallstones. Method 68 patients with gallstones who underwent surgical treatment at Meili People’s Hospital in Changshu City from December 2022 to December 2024 were included and randomly divided into two groups of 34 patients each using a random number table method. The control group received routine nursing care, while the observation group received pain nursing intervention on the basis of the control group. The pain situation, sleep quality, quality of life, and overall satisfaction with nursing care were compared between the two groups. Result Before the surgery, there was no significant difference in visual analogue scale(VAS) scores between the two groups of patients (P ＞ 0.05). However, the VAS scores of the observation group patients at 12 hours, 24 hours, and 48 hours after surgery were significantly lower than those of the control group, and the duration of pain was shorter than that of the control group, with significant differences (P ＜ 0.001). Before nursing, there was no significant difference in the Pittsburgh sleep quality index(PSQI) score and generic quality of life inventory 74(GQOLI-74) score between the two groups of patients (P ＞ 0.05). After nursing, the PSQI score of the observation group was lower than that of the control group, and the GQOLI-74 scores were all higher than those of the control group, with significant differences (P ＜ 0.05). The overall satisfaction rate of nursing care in the observation group was 94.12%, significantly higher than that in the control group (76.47%), and the difference was significant (P=0.037). Conclusion Pain nursing intervention applied to patients with gallstones has significant effects on postoperative rehabilitation, reducing their pain and improving their quality of life and sleep. Related Articles | Metrics

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Analysis of the short-term effect of breast conserving surgery and modified radical breast cancer surgery on early breast cancer patients Wang Jianjun Journal of General Surgery for Clinicians    2025, 13 (2): 34-.   Abstract （19）            Knowledge map    Save Objective To analyze the short-term effect of breast conserving surgery and modified radical surgery for breast cancer on early breast cancer patients. Method 80 cases of early breast cancer patients diagnosed and hospitalized in Chifeng Maternity Hospital from January 2022 to December 2024 were selected, all of whom were women. They were divided into groups by random number table, 40 cases in each group. The control group was treated with modified radical mastectomy for breast cancer, and the observation group was treated with breast conserving surgery+axillary sentinel lymph node biopsy. All patients were followed up for 3 months after surgery to understand the recurrence situation. Result The surgical time and hospitalization time of the observation group were shorter than those of the control group, and the intraoperative blood loss and postoperative drainage volume were less than those of the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the observation group was 7.5%, significantly lower than that in the control group (30.00%), and the difference was significant (P ＜ 0.05). Conclusion Compared with modified radical mastectomy for breast cancer, breast conserving surgery can shorten the operation time and hospital stay of early breast cancer patients, reduce the incidence of incision related complications, and reduce intraoperative bleeding and postoperative drainage volume. Related Articles | Metrics

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Clinical analysis of laparoscopic combined with rigid cholangioscopy ballistic lithotripsy for the treatment of patients with liver and bile duct stones Wang Maoqiang, Huang Tao, Zhao Jianbo, Sun Haifeng, Chen Zhengxiu, He Lingsheng, Wang Jianyu, Liang Feng, Liao Jianming, Huang Huanji Journal of General Surgery for Clinicians    2025, 13 (2): 60-.   Abstract （40）            Knowledge map    Save Objective To evaluate the clinical efficacy of laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones. Method 25 patients who received traditional surgical treatment at Fenggang Hospital in Dongguan City from January 2018 to December 2019 were selected as the control group, and 25 patients who received laparoscopic+rigid cholangioscopy ballistic lithotripsy treatment at Fenggang Hospital in Dongguan City from January 2020 to August 2024 were selected as the observation group. The perioperative parameters, immune function, complications, and liver function between the groups were evaluated. Result The surgical time, gastrointestinal function recovery time, and hospitalization time of the observation group were shorter than those of the control group. The intraoperative bleeding volume was less than that of the control group, and the incidence of residual stones was lower than that of the control group, with significant differences (P ＜ 0.01). Before surgery, there was no significant difference in IgA, IgM, IgG levels, and liver function indicators between the two groups of patients (P ＞ 0.05). After surgery, the levels of IgA, IgM, and IgG in the observation group were higher than those in the control group, while the levels of gamma glutamyl-transferase, aspartate transferase, alanine amino-transferase, conjugated bilirubin, total bile acids, and total bilirubin were lower than those in the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the control group was 24.00%, while in the observation group it was 4.00%, with a significant difference (P ＜ 0.001). Conclusion Laparoscopic and rigid cholangioscopy ballistic lithotripsy for patients with liver and bile duct stones can optimize perioperative parameters, minimize complications, and improve liver function and bile biochemical indicators. Related Articles | Metrics

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Exploring the efficacy and safety of laparoscopic cholecystectomy in the treatment of gallstones and chronic cholecystitis Chen Yongbiao Journal of General Surgery for Clinicians    2025, 13 (2): 41-.   Abstract （23）            Knowledge map    Save Objective To evaluate the clinical efficacy and safety of laparoscopic cholecystectomy in the treatment of patients with gallstones and chronic cholecystitis. Method 82 patients with gallstones and chronic cholecystitis admitted to Jurong Maternal and Child Health Hospital from January 2023 to December 2024 were selected and randomly divided into two groups using a random number table. A control group of 41 cases were treated with traditional open abdominal surgery; Observation group of 41 cases, treated with laparoscopic cholecystectomy, compared the surgical indicators and postoperative complications of patients. Result The surgical time and hospitalization time of the observation group were shorter than those of the control group [(61.18±7.52) min vs. (93.35±10.86)min, and (4.31±1.28)d vs. (9.95±2.76)d, respectively]. The intraoperative blood loss was less than that of the control group [(38.91±5.67)ml vs. (90.38±10.46)ml], and the postoperative gastrointestinal function recovery time was earlier than that of the control group [(18.98±5.17)h vs. (42.25±8.92)h], with significant differences(P ＜ 0.001). There were no complications observed in the observation group; There were 5 cases of complications in the control group, including 1 case of abdominal infection, 2 cases of incision infection, and 2 case of bile leakage. There was a significant difference between the groups (χ2=7.318，P=0.017). Conclusion Compared with traditional open surgery, laparoscopic cholecystectomy has better efficacy and higher safety in the treatment of gallstones and chronic cholecystitis. Related Articles | Metrics

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Application analysis of intervention mode of specialized nurses in surgery for mixed hemorrhoids patients Cai Juanjuan, Zhang Qiuxiang Journal of General Surgery for Clinicians    2025, 13 (2): 131-.   Abstract （23）            Knowledge map    Save Objective To explore the application of the intervention mode of specialized nurses in the surgery of mixed hemorrhoids patients and its impact on patient pain. Method 132 patients who underwent mixed hemorrhoid surgery at the First Affiliated Hospital of Guangzhou University of Chinese Medicine from May 2022 to April 2024 were selected and divided into two groups using the envelope method, with 66 patients in each group. The control group received routine nursing care, while the observation group received intervention from specialized nurses in addition to the control group. Compare the medical coping strategies, pain levels, psychological stress responses, quality of life, and incidence of complications between two groups of patients. Result Before intervention, there was no significant difference in medical coping modes questionnaire(MCMQ) score, visual analogue scale(VAS) score, perceived stress scale(PSS)-10 score, and short form 36(SF-36) score between the two groups of patients (P ＞ 0.05). After intervention, both groups of patients showed improvement in MCMQ scores compared to before intervention, with reduced pain and psychological stress responses, and improved quality of life, with significant differences (P ＜ 0.05). After intervention, the face score of the observation group patients was higher than that of the control group, and the avoidance and surrender scores were lower than those of the control group. In addition, the VAS score and PSS-10 score were lower than those of the control group, and the SF-36 score was higher than that of the control group, with significant differences (P ＜ 0.001). The total incidence of complications in the observation group was 3.03%, significantly lower than that in the control group (12.12%), with a significant difference (P=0.048). Conclusion The intervention mode of specialized nurses has a good effect on patients with mixed hemorrhoids during surgery, which can improve their medical coping style, alleviate their pain and psychological stress reactions, help improve their quality of life, and reduce the risk of complications. Related Articles | Metrics

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The application effect of zero defect nursing intervention in patients with gastric bleeding and its impact on self-management level Li Heng Journal of General Surgery for Clinicians    2025, 13 (2): 101-.   Abstract （20）            Knowledge map    Save Objective To explore the application effect of zero defect nursing intervention in patients with gastric bleeding and its impact on self-management level. Method 76 patients with gastric bleeding admitted to the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from August 2023 to September 2024 were selected and divided into two groups using the envelope method, with 38 patients in each group. The control group received routine nursing care, while the observation group received zero defect nursing intervention. Both groups completed 2 weeks of nursing care. Compare the self-care ability, level of hope, and satisfaction between two groups. Result Before the intervention, there was no significant difference in self-care ability and hope level between the two groups of patients (P ＞ 0.05). After intervention, the self-care ability and hope level of both groups of patients were significantly improved compared to before intervention (P ＜ 0.05), and the behavior, cognition, and environmental scores of the observation group were higher than those of the control group. The positive attitude, positive action, intimate relationship, and total score of the observation group were higher than those of the control group, and the diff erences were significant (P ＜ 0.001). After intervention, the satisfaction of the observation group with all aspects was better than that of the control group, and the difference was significant (P ＜ 0.05). Conclusion Zero defect nursing intervention has shown good results in patients with gastric bleeding, improving their self-care ability and helping to enhance their hope level, resulting in higher nursing satisfaction. Related Articles | Metrics

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Treatment with antibody-drug conjugate drugs for breast cancer: analysis of progress and future choices Zhang Yang, Zhang Xinran, Ao Dongxu, Cai Jun Journal of General Surgery for Clinicians    2025, 13 (3): 65-.   Abstract （20）            Knowledge map    Save Breast cancer, as the most common malignant tumors among women globally, has seen an increasing incidence rate year by year, posing a serious threat to women's health. Traditional treatment methods for breast cancer still have many limitations. Antibody-drug conjugates (ADCs) are a new type of targeted drugs for treating breast cancer, which have shown remarkable efficacy in the treatment of HER2-positive breast cancer. At the same time, important progress has also been made in the treatment of advanced triple-negative breast cancer (TNBC) and some breast cancers with low HER2 expression, providing more options for people with different molecular subtypes of breast cancer. This article mainly elaborates and discusses the latest progress after the treatment with ADC drugs for breast cancer and the future development directions. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2025, 13 (3): 99-.   Abstract （9）            Knowledge map    Save Related Articles | Metrics

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Journal of General Surgery for Clinicians    2025, 13 (3): 103-.   Abstract （12）            Knowledge map    Save Related Articles | Metrics

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Effect of zhenqi fuzheng granules combined with probiotics on intestinal mucosal barrier function in patients with early gastric cancer after nutritional support Zong Mingzhu, Yu Haiwen Journal of General Surgery for Clinicians    2025, 13 (3): 71-.   Abstract （24）            Knowledge map    Save Objective To explore the impact of zhenqi fuzheng granules combined with probiotics on intestinal mucosal barrier function in patients undergoing nutritional support following early gastric cancer surgery. Method From August 2021 to August 2023, 100 patients with early gastric cancer in Huai'an First Hospital Affiliated to Nanjing Medical University were selected and randomly divided into two groups, 50 cases in each group. The control group was treated with early postoperative enteral nutrition combined with probiotics, while the observation group was treated with zhenqi fuzheng granules based on this. The postoperative recovery indexes of the two groups were compared, and the changes of nutritional status and intestinal mucosal barrier function before and after intervention were compared. Result The recovery time of bowel sounds, the first exhaust time and the hospitalization time of the observation group were shorter than those of the control group, the difference was significant (P ＜ 0.01), but there was no significant difference in the indwelling time of catheter and the first ambulation time between the two groups (P ＞ 0.05). Before intervention, there was no significant difference in the levels of nutritional indicators and intestinal mucosal barrier function related indicators between the two groups (P ＞ 0.05). After the intervention, the nutritional index levels of the two groups were improved, and the levels of transferrin, albumin and prealbumin in the observation group were higher than those in the control group; The levels of intestinal mucosal barrier function related indicators in the two groups were improved, and the levels of intestinal fatty acid binding protein, procalcitonin and D-lactic acid in the observation group were lower than those in the control group, with significant differences (P ＜ 0.001). Conclusion Zhenqi fuzheng granules combined with  probiotics has positive significance on nutrition and intestinal mucosal barrier function in patients with early gastric cancer after operation. Related Articles | Metrics

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Relationship between coping style and health behavior of patients after cholecystectomy and its impact analysis Cao Qingqing Journal of General Surgery for Clinicians    2025, 13 (3): 7-.   Abstract （12）            Knowledge map    Save Objective To explore the relationship between coping style and health behavior of patients after cholecystectomy and its impact analysis. Method 94 patients who underwent cholecystectomy in Pizhou Dongda Hospital from January 2023 to October 2024 were selected by convenient sampling method. The general information questionnaire, the medical coping style questionnaire and the health promoting lifestyle scale were used to investigate them, and the scores of coping style and health promoting lifestyle of patients after cholecystectomy and their correlation and influence were analyzed. Result the health promoting lifestyle score of patients with cholecystectomy was (106.44 ± 15.94), and the yield dimension score, avoidance dimension score and face dimension score were (7.76±2.15), (9.96±2.37) and (22.85±4.61), respectively. There were signifi cant diff erences in the scores of health promoting lifestyle in patients' economic income (F=2.366, P=0.022), educational level (F=2.588, P=0.015), coping style (F=11.352, P＜0.001), smoking (t=4.050, P＜0.001), and basic diseases (t=2.305, P=0.026). Economic income, education level, coping style, smoking and basic diseases were the influencing factors of health promoting lifestyle scores of patients after cholecystectomy (P ＜ 0.05). Conclusion There is a significant correlation between health promoting lifestyle and coping style of patients after cholecystectomy. Related Articles | Metrics

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Effect of different reconstruction methods after distal gastrectomy on postoperative quality of life in patients with gastric cancer Xu Jiayi, Hu Renhao¹, Cui Ximao¹, Ma Chiye¹, Zhang Shun¹, Jiang Xiaohua¹ Journal of General Surgery for Clinicians    2025, 13 (3): 35-.   Abstract （19）            Knowledge map    Save Objective To compare postoperative quality of life between Billroth Ⅱ and uncut Roux-en-Y anastomosis in patients undergoing radical distal gastrectomy for gastric cancer. Method The clinical data of 60 patients who received radical distal gastrectomy in Dongfang Hospital Affiliated to Tongji University from November 2019 to August 2022 were collected. The patients were divided into two groups according to the postoperative digestive tract reconstruction: Billroth Ⅱ anastomosis group (B- Ⅱ group) and uncut Roux-en-Y anastomosis group (uncut R-Y group). The Chinese version of the postgastrectomy syndrome assessment scale (PGSAS)-37 was used to evaluate and compare the differences between the two groups in the field of symptoms, life status and quality of life. Result A total of 60 patients were included in this study, including 26 patients in group B- Ⅱ and 34 patients in uncut R-Y group. There were no significant differences in age, gender and postoperative follow-up time distribution between the two groups (P ＞ 0.05). In terms of surgical methods, the proportion of laparoscopic surgery (including laparoscopic assisted surgery and total laparoscopic surgery) in the uncut R-Y group was significantly higher than that in the B- Ⅱ group (χ2=17.532, P=0.001). PGSAS-37 score showed that the gastric acid reflux symptoms in the uncut R-Y group were significantly better than those in the B-Ⅱ group (P=0.044); There was no significant difference in other symptoms, life status and quality of life between the two groups (P ＞ 0.05). Conclusion Uncut Roux-en-Y anastomosis demonstrated superiority over B- Ⅱ anastomosis regarding acid reflux symptoms after distal gastrectomy. However, no significant differences were found in other quality of life aspects. Related Articles | Metrics

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Comparison of the effect and safety of laparoscopic middle approach and caudal medial approach in one-way loop surgery in patients with right colon cancer Su Yanlin Journal of General Surgery for Clinicians    2025, 13 (3): 41-.   Abstract （19）            Knowledge map    Save Objective To study the effect and safety of laparoscopic middle approach and caudal medial approach in the operation of right colon cancer. Method 85 patients with right colon cancer in Yulin Third People's Hospital from April 2022 to April 2024 were selected. All patients received radical resection of right colon cancer. They were divided into control group and observation group according to different approaches. The control group (n=42) was treated with intermediate approach surgery, and the observation group (n=43) was treated with oneway loop surgery via caudal medial approach. The perioperative indicators, tumor markers, stress indicators and complications of the two groups were compared. Result The number of lymph node dissection in the observation group was more than that in the control group, and the operation time was shorter than that in the control group, and the intraoperative blood loss was less than that in the control group, the differences were significant (P ＜ 0.05). After operation, the carcinoembryonic antigen, carbohydrate antigen 125, carbohydrate antigen 19-9, cortisol, adrenocorticotropic hormone, norepinephrine in the observation group were signifi cantly lower than those in the control group (P ＜ 0.05). The conversion rate of laparotomy (0 vs 9.52%) and the total complication rate (6.98% vs 23.81%) in the observation group were lower than those in the control group, and the differences were significant (P ＜ 0.05). Conclusion The medial caudal approach of one-way loop laparoscopic surgery for right colon cancer needs shorter time, less intraoperative blood loss, which is more conducive to the postoperative recovery of patients, and the operation idea is clear, which can avoid repeated overturning of the mesentery and intestines, and is more conducive to the completion of lymph node dissection. Related Articles | Metrics

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The influence of single-incision laparoscopic radical resection of colon cancer on postoperative immune function and stress response in elderly patients with colorectal cancer Cai Desheng, Bao Chuanqing, Wu Ji Journal of General Surgery for Clinicians    2025, 13 (3): 46-.   Abstract （20）            Knowledge map    Save Objective To investigate the effect of single incision laparoscopic radical resection of colon cancer on postoperative immune ability and stress response in elderly patients with colorectal cancer. Method A total of 68 patients with colorectal cancer who received single incision laparoscopic treatment in the second geriatric hospital of Wuxi from May 2022 to May 2025 were selected and randomly divided into two groups, 34 cases in each group. The conventional group received conventional open surgery, and the experimental group received single incision laparoscopic radical resection of colon cancer. The physical signs, cellular immune function and stress response index levels of the two groups at different time points were compared. Result There were no signifi cant differences in heart rate, mean arterial pressure, pulse oxygen saturation (SpO2) and respiratory rate between the two groups before anesthesia, when anesthesia was successful and 72 hours after operation (P ＞ 0.05). At the end of operation and 24 hours after operation, the heart rate of the experimental group was lower than that of the conventional group, and the mean arterial pressure, SpO2 and respiratory rate of the experimental group were higher than those of the conventional group, with significant differences (P ＜ 0.05). There were no signifi cant diff erences in the percentages of CD3+T cells, CD4+T cells, cortisol and interleukin-6 between the two groups before and after anesthesia (P ＞ 0.05). At the end of operation, 24 hours and 72 hours after operation, the percentages of CD3+ T cells and CD4+ T cells in the experimental group were higher than those in the conventional group, and the levels of cortisol and interleukin-6 were lower than those in the conventional group, with significant differences (P ＜ 0.05). Conclusion Compared with traditional open surgery, single incision laparoscopic radical resection of colon cancer has less impact on elderly patients with colorectal cancer, can better stabilize the immune ability of patients, and the stress response is mild. Related Articles | Metrics