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Application of percutaneous abdominal puncture and drainage in the diagnosis and treatment of closed abdominal injury combined with splenic contusion and laceration WEI Licheng Journal of General Surgery for Clinicians    2022, 10 (4): 41-.   Abstract （30）            Knowledge map    Save Objective To explore the effect of percutaneous abdominal puncture and drainage in the diagnosis and treatment of closed abdominal injury combined with splenic contusion and laceration. Method From January 2016 to June 2021, 52 patients with closed abdominal injury combined with splenic contusion and laceration admitted to Hechi People's Hospital were selected for non-surgical treatment through percutaneous abdominal puncture and drainage. The clinical data of the patients were analyzed retrospectively, and the clinical diagnosis and treatment results, complications and improvement of quality of life were counted. Result Among 52 patients with closed abdominal injury and splenic contusion and laceration, 51 patients had positive puncture results. The positive rate and accuracy of puncture were 98.08%. One case was false positive due to puncture complications. The incidence of puncture complications was 1.92%. Moreover, none of the patients in this study had non therapeutic laparotomy and death. Among them, except for 1 case of secondary bleeding and 1 case of delayed intestinal perforation, the remaining 50 cases were cured and discharged after conservative treatment, and the success rate of conservative treatment was 96.15%. After 3 months of follow-up, there were no complications except 1 case of adhesive intestinal obstruction, and the quality of life score of the patients was significantly higher than that before discharge (P ＜ 0.05). Conclusion Percutaneous abdominal puncture and catheter drainage for the treatment of abdominal closed injury combined with splenic contusion and laceration has a high positive rate of puncture and diagnostic accuracy. At the same time, it can reduce puncture complications, improve the success rate of conservative treatment, and improve the quality of life of patients. Related Articles | Metrics

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Observe the clinical effect of the treatment of horseshoe perianal abscess via the approach between the sphincter internal and the sphincter externus WANG Chengxing, LI Xiaoping, ZHAO Jinglin, LI Shangren, TAN Qunying, HE Yaoming Journal of General Surgery for Clinicians    2021, 9 (2): 24-.   Abstract （49）            Knowledge map    Save Objective To investigate the efficacy of treatment of perianal horseshoe abscess via the approach between the sphincter internal and the sphincter externus. Methods From December 2014 to December 2019, 50 cases of horseshoe perianal abscess in gastrointestinal surgery of Jiangmen Central Hospital were selected. According to the random number table, patients with perianal horseshoe abscess were randomly divided into two groups, the experimental group (by the approach between the sphincter internal and the sphincter externus) 25 cases and the control group (by classical approach) 25 cases. The operation time, intraoperative blood loss, duration of the postoperative pain, hospital stay, healing time of surgical incision, anal function, anal morphology, recurrence rate, anal fistula rate and complex anal fistula rate of two groups were recorded and analyzed. Results There were statistical differences in the terms of operation time, duration of the postoperative pain, healing time of surgical incision, anal function, anal morphology anal fistula rate and complex anal fistula rate, experiment group is much better than that of the control group (P<0.05); However, there were no statistical differences in the terms of intraoperative blood loss, hospital stay and recurrence rate between the two groups (P>0.05). Conclusion Compared with the traditional approach, it has good clinical effect to treat horseshoe perianal abscess through the approach between the sphincter internal and the sphincter externus. Related Articles | Metrics

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Study on the effect of laparoscopic radical resection of colorectal cancer in the treatment of elderly colorectal cancer YE Nianyuan, XI Cheng, WANG Yibo, ZHANG Zheng Journal of General Surgery for Clinicians    2022, 10 (2): 17-.   Abstract （39）            Knowledge map    Save Objective To explore the clinical effect of laparoscopic radical resection of colorectal cancer in the elderly. Method 100 elderly patients with colorectal cancer treated in Wujin Hospital Affiliated to Jiangsu University from December 2016 to March 2021 were selected as the research object. They were divided into control group (n=50) and study group (n=50) by different surgical methods. The patients in the control group were treated with traditional open surgery, and the patients in the study group were treated with laparoscopic radical resection of colorectal cancer. The operation implementation, postoperative complications, quality of life and gastrointestinal function were compared between the two groups. Result The scores of postoperative quality of life in the two groups were significantly higher than those before intervention, and the scores of patients in the study group were higher than those in the control group (P ＜ 0.05); the incidence of postoperative complications in the study group was 14.00%, which was significantly lower than that in the control group (P ＜ 0.05); during the operation, the operation time, intraoperative bleeding, postoperative exhaust time, postoperative hospital stay and resection length in the study group were significantly better than those in the control group (P ＜ 0.05); the levels of motilin and gastrin in the study group were significantly higher than those in the control group (P ＜ 0.05). Conclusion The clinical effect of laparoscopic radical resection of colorectal cancer in elderly patients is better. It can effectively reduce the incidence of complications in elderly patients, with less trauma and higher safety. It is of positive significance to improve the quality of life of elderly patients with colorectal cancer. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2021, 9 (3): 47-.   Abstract （38）            Knowledge map    Save Related Articles | Metrics

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Application of Dai medicine sitting and medicine therapy in the treatment of hemorrhoids and rectal prolapse LI Xiang, LUO Ping Journal of General Surgery for Clinicians    2022, 10 (3): 26-.   Abstract （46）            Knowledge map    Save Anorectal disease is a common and frequent clinical disease. Hemorrhoids and rectal prolapse are both anorectal diseases that occur in the anorectal area, and they often affect people's quality of life and physical health. The Dai people have a unique understanding and rich clinical experience in the treatment of hemorrhoids and prolapse of anus in anorectal diseases in the long-term process of disease prevention, treatment and life practice. Among them, Nanya (sitting medicine therapy) is an external therapy commonly used by Dai doctors in the treatment of hemorrhoids and prolapse of the anus. This article reviews the application of Dai medicine difficult and elegant (sitting medicine therapy) in the treatment of anorectal disease hemorrhoids and rectal prolapse. Related Articles | Metrics

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Journal of General Surgery for Clinicians    2022, 10 (3): 186-.   Abstract （33）            Knowledge map    Save Related Articles | Metrics

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Application effect of five element music therapy combined with 6 minute walking test in perioperative accelerated rehabilitation surgical nursing of rectal cancer patients #br# CHEN Chuxia Journal of General Surgery for Clinicians    2022, 10 (2): 81-.   Abstract （23）            Knowledge map    Save Objective To explore the effect of five element music therapy combined with 6 minute walking test (6MWT) in perioperative accelerated rehabilitation surgery nursing of rectal cancer patients. Method From June 2019 to January 2021, 90 patients with rectal cancer who needed radical resection of rectal cancer in Huazhong University of Science and Technology Union Shenzhen Hospital were selected as the research objects. They were numbered according to the order of admission and divided into experimental group and control group according to the random number table, with 45 cases in each group. The control group received routine perioperative accelerated rehabilitation surgical nursing, while the experimental group received five element music therapy combined with 6MWT. The effect of 6MWT before and after intervention, postoperative eating time, exhaust time, length of hospital stay and postoperative complications were compared between the two groups. Result There was no significant difference between the two groups before the intervention (P ＞ 0.05). The 6MWT result after the intervention in the experimental group was (375.07 ± 21.95) m, which was significantly higher than that before the intervention (228.66 ± 15.69) m, and also higher than that in the control group (P ＜ 0.05). The postoperative eating time, exhaust time and hospital stay in the experimental group were shorter than those in the control group, and the incidence of postoperative complications was also lower than that in the control group (P ＜ 0.05). Conclusion Five element music therapy combined with 6MWT nursing can accelerate the postoperative rehabilitation of patients with rectal cancer, reduce postoperative complications and improve the postoperative clinical outcome. Related Articles | Metrics

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Application of preservation of serratus anterior fascia of pectoralis major in immediate breast reconstruction LI Xiaohong, LIN Huqiang, LAI Qing Journal of General Surgery for Clinicians    2022, 10 (3): 55-.   Abstract （25）            Knowledge map    Save Objective To study the effect of preserving serratus anterior fascia of pectoralis major in immediate breast reconstruction. Method Twenty patients who received early breast cancer treatment in People's Hospital of Yangchun City from April 2021 to March 2022 were randomly selected as the research subjects, and divided into two groups according to the numerical expression method. Among them, 10 patients who received latissimus dorsi flap metastatic breast reconstruction surgery were selected. As the control group, another 10 patients who underwent immediate breast reconstruction with serratus anterior fascia preservation were set as the observation group, and the operation efficiency, appearance satisfaction, and complication rates were compared between the two groups. Result After surgical intervention, the effective rate of operation in the observation group was 90%, and the effective rate in the control group was 60%. There was a significant difference in the indicators between the two groups (P＜0.05). Appearance satisfaction was 70%, and the comparison of satisfaction between the two groups was statistically significant (P ＜ 0.05). The incidence of complications in the observation group was 10%, and the incidence of complications in the control group was 40%. Significance (P ＜ 0.05). Conclusion The effect of preserving the serratus anterior fascia of the pectoralis major muscle in immediate breast reconstruction is very significant, which improves the patient's appearance satisfaction to a certain extent, and the operation is less traumatic and safe, and reduces the occurrence of complications. Related Articles | Metrics

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To investigate the safety of spleen preserving laparoscopic pancreaticotomy with Kimura method in the treatment of patients with spleen and pancreatic tail lesions HONG Han, XU Xiaoyong, JIN Zhengkang, LI Gaochao, FEI Qiang Journal of General Surgery for Clinicians    2022, 10 (3): 84-.   Abstract （15）            Knowledge map    Save Objective To investigate the efficacy and safety of Kimura method in laparoscopic pancreatectomy with spleen preservation. Method The clinical data of 32 patients with splenopancreatic body caudal lesions treated in Suzhou Hospital Affiliated to Nanjing Medical University from January 2018 to December 2021 were retrospectively analyzed. The 20 patients treated with Kimura method of spleen preserving laparoscopic pancreatectomy were the observation group, and the 12 patients treated with traditional surgery were the reference group. The relevant clinical indicators and complications of the two groups were compared. Result The amount of intraoperative bleeding in the observation group was less than that in the reference group, and the operation time, postoperative ambulation time, postoperative exhaust time, postoperative drainage time and hospitalization time were shorter than those in the reference group (P ＜ 0.05); the incidence of complications in the observation group was lower than that in the reference group（ P ＜ 0.05）. Conclusion Kimura method of laparoscopic tail and body pancreatectomy with spleen preservation is more effective in the treatment of patients. Compared with the traditional surgical treatment, Kimura method of laparoscopic tail and body pancreatectomy with spleen preservation causes less trauma and lower risk of complications, which can effectively promote the postoperative recovery of patients. Related Articles | Metrics

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Clinical study on different ultrasonic signs in predicting lymph node metastasis of thyroid papillary carcinoma LIU Caihong, HAO Ying, ZHAO Zhenlong, WEI Ying, PENG Lili, LI Yan, YU Ming’an Journal of General Surgery for Clinicians    2023, 11 (1): 8-.   Abstract （61）            Knowledge map    Save Objective To study the ultrasonographic features of papillary thyroid carcinoma nodules (PTC) with lymph node metastasis (LNM). Method The data of patients with PTC who underwent thermal ablation from July 2019 to December 2020 were retrospectively studied. The patients were divided into LNM group and non-LNM group. The imaging features and parameters between the two groups both on conventional ultrasound and contrast-enhanced ultrasound were compared. Result A total of 91 patients with PTC were included, including 31 cases in the LNM group and 60 cases in the non-LNM group. In the LNM group, the proportion of nodules with length/width ratio larger than 1.0 or with microcalcification were higher than those in the non-LNM group, and the difference were statistically significant (P ＜ 0.05); The peak intensity (PI)difference was lower than that in the non-LNM group (P ＜ 0.05). ROC curve analysis was performed to test the diagnostic efficiency of PI difference to diagnose PTC with LNM. The area under the curve was 0.63, the optimum critical value was -7.3, the sensitivity was 42% and the specificity was 43%. Conclusion The imaging features and parameter showed significant differences between the LNM group and non-LNM group. The above results may be helpful to predict the biological characteristics of PTC. Related Articles | Metrics

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Analysis of risk factors for lymph node metastasis in the central region of cN0 thyroid micropapillary carcinoma ZHAO Bitao Journal of General Surgery for Clinicians    2023, 11 (1): 14-.   Abstract （28）            Knowledge map    Save Objective To investigate the risk factors of lymph node metastasis in the central region of cN0 thyroid micropapillary carcinoma. Method The clinical data of 106 patients with cN0 thyroid micropapillary carcinoma in Jiangmen Xinhui District People's Hospital from May 2020 to November 2021 were retrospectively analyzed. According to the lymph node metastasis in the central region, they were divided into two groups: metastatic group (49 cases) and non-metastatic group (57 cases). The risk factors of lymph node metastasis in the central region of patients were analyzed. Result Of the 106 patients, 49 had lymph node metastasis in the central region and 57 had no metastasis. The proportion of males, tumor location, microcalcification and invasion of capsule in the metastatic group was higher than that in the non-metastatic group (P ＜ 0.05), the proportion of patients with age ＜ 55 years old and tumor diameter ＜ 5 mm was lower than those without metastasis (P ＜ 0.05), however, there was no significant difference in the proportion of patients with nodular goiter and Hashimoto's thyroiditis between the two groups (P ＞ 0.05). Multivariate logistic regression analysis showed that the risk factors of lymph node metastasis in the central region of 106 patients included male, microcalcification and capsule invasion (P ＜ 0.05). Conclusion The risk factors of lymph node metastasis in the central region of cN0 thyroid micropapillary carcinoma include male, microcalcification, and invasion of capsule. Preventive and therapeutic dissection of lymph nodes in the central region is recommended. Related Articles | Metrics

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Diagnosis and treatment of 6 cases postsigmoidostomic hernia after colostomy WANG Yongle, ZHANG Jie, LI Wen, SUN Qinli, YANG Liguang Journal of General Surgery for Clinicians    2023, 11 (1): 45-.   Abstract （21）            Knowledge map    Save Objective To explore the clinical characteristics, diagnosis and treatment of postsigmoidostomic hernia after colostomy for rectal cancer. Method The clinical data of 6 patients with postsigmoidostomic hernia developed after colostomy for rectal cancer in Linyi Central Hospital from January 2018 to December 2021 were retrospectively analyzed. Result The sigmoid mesocolon at the stoma and the left parietal abdominal wall were continuously sutured and fixed in 6 patients. The operation took 46 ～ 210 minutes, the amount of bleeding was not much, there were no complications related to the operation, and there was no hernia of the groove beside the sigmoid colostomy. Conclusion Postsigmoidostomic hernia is a rare complication after colostomy. It is important to perform abdominal CT scanning as early as possible from the clinical history and physical findings, and to determine the surgical indication. Related Articles | Metrics

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Influence of tumor cell positive in peripheral blood circulation on perioperative coagulation function in operable breast cancer patients ZHANG Chenglei Journal of General Surgery for Clinicians    2023, 11 (2): 2-.   Abstract （28）            Knowledge map    Save Objective To analyze the influence of positive circulating tumor cell (CTC) in peripheral blood of operable breast cancer patients on coagulation function in perioperative period. Method 80 cases of breast cancer patients who underwent surgical treatment in Zhanjiang Central People's Hospital from July 2019 to March 2020 were selected for the study. According to the level of tumor cells in their peripheral blood circulation, they were divided into positive group (preoperative CTC positive) and negative group (preoperative CTC negative). Before operation, on the 1st, 3rd, 7th and 14th day after operation, the patients were tested by routine coagulation function indexes and thromboelastogram. The results of coagulation function and thrombelastography were compared between the two groups. Result Among the 80 patients, 12 were positive for CTC, with a positive detection rate of 15.00%. There were no significant difference in FIB and DD levels between positive group and negative group at different time before and after operation (P ＞ 0.05). The prothrombin time, activated partial thrombin time, thromboelastogram reaction time, and coagulation time in the positive group were significantly lower than those in the negative group, and the platelet count, thromboelastogram maximum amplitude, and Angle angle were significantly higher than those in the negative group, with significant differences (P ＜ 0.05). Conclusion Patients with operable breast cancer who have positive circulating tumor cells before operation have abnormal coagulation function during the perioperative period and have potential risk of deep vein thromboembolism. Related Articles | Metrics

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The choice and efficacy of treatment for elderly patients with choledocholithiasis combined with cholecystolithiasis LIU Dongdong, YU Anxing, LI Bin Journal of General Surgery for Clinicians    2023, 11 (2): 7-.   Abstract （42）            Knowledge map    Save Objective To explore the choice and efficacy of treatment for elderly patients with choledocholithiasis combined with cholecystolithiasis. Method The elderly patients with cholecystolithiasis and choledocholithiasis diagnosed in Pingdu People's Hospital hospital from February 2017 to November 2019 were selected and randomly divided into the observation group (n=34) and the control group (n=32). The observation group was treated with step-by-step endoscopic sphincteropapillotomy(EST) combined with laparoscopic cholecystectomy (LC), and the control group was treated with LC combined with laparoscopic common bile duct exploration T-tube choledochotomy (LCBDE). The total operation time, indwelling time of drainage tube after operation, intraoperative bleeding, postoperative hospital stay, conversion from laparoscopy to laparotomy, stone removal rate, and postoperative complications (including fever, bile leakage, pancreatitis) were compared between the two groups. Result The total operation time, drainage tube retention time, and postoperative hospitalization time of patients in the observation group were shorter than those in the control group, with less intraoperative bleeding and lower conversion rate to laparotomy in the observation group (P ＜ 0.05). There was no significant difference between the two groups in stone removal rate and postoperative complication rate (P ＞ 0.05). Conclusion Both EST+LC and LC+LCBDE can effectively treat the elderly patients with cholecystolithiasis and choledocholithiasis, but in county hospitals with both technology and equipment, EST+LC is more beneficial for elderly patients with choledocholithiasis and choledocholithiasis. Related Articles | Metrics

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Analysis of the efficacy of linaclotide in patients with functional constipation MA Lin, CHEN Yongqiang, WANG Cai Journal of General Surgery for Clinicians    2023, 11 (2): 11-.   Abstract （32）            Knowledge map    Save Objective To explore the efficacy of linaclotide in treating colonic obstruction in patients with functional constipation. Method From June 2019 to June 2022, 80 patients with colonic obstruction caused by functional constipation who were diagnosed and treated by the Eighth People's Hospital of Qingdao City were randomly divided into a control group and an observation group, with 40 patients in each group. The patients in the control group received routine treatment, including general treatment, anal exhaust, and enema. The observation group was treated with linaclotide on the basis of the control group. Compare the efficacy, frequency of defecation, stool characteristics, abdominal distension, sense of difficulty in defecation, abdominal pain scores, constipation specific quality of life scores, and the occurrence of adverse reactions between the two groups. Result The efficacy of the observation group was 95.00%, significantly higher than that of the control group (77.50%), with a significant difference (P ＜ 0.05). Before treatment, there was no significant difference between the two groups in stool characteristics, defecation frequency, abdominal distension, sense of difficulty in defecation, abdominal pain scores, and constipation specific quality of life scores (P ＞ 0.05); After treatment, the stool characteristics, defecation frequency, and abdominal distension, defecation exertion, abdominal pain scores, and constipation specific quality of life scores of the two groups of patients were significantly increased, and the range of change in the observation group was significantly higher than that in the control group (P ＜ 0.05). During the treatment period, the incidence of adverse reactions was 12.50% in the observation group and 10.00% in the control group, with no significant difference (P ＞ 0.05). The recurrence rate in the observation group was 2.50%, significantly lower than that in the control group (15.00%), with a significant difference (P ＜ 0.05). Conclusion Linaclotide is effective in improving the clinical outcomes of patients with functional constipation and colonic obstruction. Related Articles | Metrics

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Comparison of transabdominal preperitoneal prosthesis and flat plate tension-free hernia repair operation in the repair of bilateral inguinal hernia LI Dongfang, CAI Dejun, CHEN Yonghan, JIANG Xiaosong Journal of General Surgery for Clinicians    2023, 11 (3): 42-.   Abstract （10）            Knowledge map    Save Objective To investigate the efficacy of transabdominal preperitoneal prosthesis(TAPP) versus flat plate tension-free hernia repair(Lichtenstein) surgery in bilateral inguinal hernia repair. Method A retrospective analysis of 75 patients with bilateral inguinal hernia admitted to the hospital from January 2019 to April 2022, of which 40 were treated with Lichtenstein surgery and 35 were treated with TAPP. The perioperative condition, shortterm treatment effect, recurrence rate and complication rate of the two groups were compared. Result The surgical time in the TAPP group was higher than that in the Lichtenstein group, The postoperative 24-hour pain score, postoperative bedtime, postoperative exhaust time, and hospital stay in the TAPP group were significantly lower than those in the Lichtenstein group, The hospitalization expenses of the TAPP group were higher than those of the Lichtenstein group, the differences are significant (P ＜ 0.05). On the 1st postoperative day, white blood cell count in the TAPP group was (4.98±1.02)×109/L, tumor necrosis factor-α lever was(35.13±4.52)pg/L, and C-reactive protein lever was (3.78±0.62) mg/L, which were all lower than those in the Lichtenstein group [(5.63±1.38)×109/L, (42.17±4.31)pg/L, and (4.83±0.70)mg/L, respectively], the differences are significant (P ＜ 0.05). The recognition rate of patients in the TAPP group was 91.43%, higher than that in the Lichtenstein group (85.00%), but there was no statistically significant difference between the groups (P ＞ 0.05). 3 patients in the TAPP group experienced complications, with a total incidence rate of 8.5%;6patients in the Lichtenstein group experienced complications, with a total incidence rate of 15.0%. There was no statistically significant difference between the two groups(P ＞ 0.05). All cases were followed up for 19 months after surgery, In the TAPP group, 2 cases (5.71%) recurred at 7 and 17 months respectively; 1 case (2.50%) in the Lichtenstein group relapsed 13 months after surgery. There was no statistically significant difference in the recurrence rate between the two types of surgery (P ＞ 0.05). Conclusion TAPP and Lichtenstein surgery have a definite clinical effect on bilateral inguinal hernia, and the complication rate is equivalent, but patients treated with TAPP recover faster after surgery. Related Articles | Metrics

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The relationship between immune cells and microenvironment of colorectal cancer ZHANG Zheng, JIANG Rong, Journal of General Surgery for Clinicians    2023, 11 (4): 17-.   Abstract （6）            Knowledge map    Save As an important digestive organ of human body, the intestinal microenvironment is a very complex environment, which plays an important role in regulating intestinal metabolism, immunity and protecting intestinal epithelial barrier. Tumor microenvironment (TME) of intestinal tumors is highly complex, which is composed of stromal cells, tumor cells, immune cells, fibroblasts and microorganisms, and deeply affects the occurrence, development and metastasis of tumors. This paper summarizes the relationship between immune cells (T cells, macrophages, neutrophils, natural killer cells) in TME and tumor cells, and analyzes the role of immune cells in TME in tumor (anti-tumor, promoting tumor growth, etc.) in order to fully understand the relationship between immune cells and tumors in TME and provide new strategies for clinical treatment of colorectal cancer patients. Related Articles | Metrics

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The impact of laparoscopic radical resection of rectal cancer with preservation of left colic artery on gastric function and complications in patients Cheng Zhigang Journal of General Surgery for Clinicians    2024, 12 (1): 41-.   Abstract （8）            Knowledge map    Save Objective To explore the effects of preserving the left colic artery (LCA) in laparoscopic radical resection of rectal cancer on gastric function and complications in patients. Method 57 patients who underwent laparoscopic radical resection of rectal cancer admitted to Dunhua Hospital from December 2020 to November 2023 were randomly divided into a control group (28 cases) and an observation group (29 cases). The control group did not retain LCA during surgery, while the observation group retained LCA during surgery. Compare the incidence of complications, gastric function, urinary function, and anorectal dynamics between two groups. Result Compared with preoperative, the levels of gastrin, motilin, pepsinogen Ⅰ , and calcitonin gene related peptide (CGRP) in both groups of patients increased 30 days after surgery, and the levels of gastrin, motilin, pepsinogen Ⅰ , and CGRP in the observation group were higher than those in the control group. Compared with preoperative data, the resting pressure and maximum systolic pressure of the anal canal in both groups of patients decreased 30 days after surgery, and the resting pressure and maximum systolic pressure of the anal canal in the observation group were higher than those in the control group, with significant differences (P ＜ 0.05). On the 7th day after surgery, the overactive bladder symptom scale (OABSS) scores of both groups of patients decreased compared to before surgery, and the OABSS scores of the observation group were lower than those of the control group, with significant differences (P ＜ 0.05). The total incidence of postoperative complications in the observation group was lower than that in the control group, with a significant difference (P ＜ 0.05). Conclusion Preserving LCA during laparoscopic radical surgery can improve the anorectal motility indicators of rectal cancer patients, quickly restore their gastric and urinary functions, and reduce the risk of complications. Related Articles | Metrics

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Comparison of clinical efficacy between ligation of intersphincteric fistula and traditional anal fistula incision in the treatment of low simple anal fistula Yang Shilei Journal of General Surgery for Clinicians    2024, 12 (1): 46-.   Abstract （3）            Knowledge map    Save Objective To explore the clinical efficacy of ligation of intersphincteric fistula tract in the treatment of low simple anal fistula. Method 46 patients with low simple anal fistula admitted to Donghai County Traditional Chinese Medicine Hospital in Lianyungang City from February 2020 to February 2023 were selected. Divided into a control group and an observation group using a random number table method, with 23 cases in each group. The control group underwent traditional anal fistula incision surgery, while the observation group underwent LIFT surgery. The clinical efficacy and postoperative recovery of the two groups of patients were compared. Result There was no significant difference in the total effective rate between the two groups (P ＝ 0.310). The wound healing time and hospitalization duration of the observation group were shorter than those of the control group, and the VAS score was lower than that of the control group, with significant differences (P ＜ 0.05). There was no significant difference in preoperative anal incontinence Wexner scores between the two groups of patients. After 1 month and 3 months of surgery, the observation group had lower anal incontinence Wexner scores than the control group, and the difference was significant (P ＜ 0.05). Conclusion The treatment of low position simple anal fistula with LIFT surgery can alleviate patient pain to a certain extent, preserve the function of the patient's sphincter, and lead to faster recovery. Related Articles | Metrics

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Clinical application of hepatic artery infusion chemotherapy in advanced liver cancer ZHANG Yongzhen, ZHAO Mengpeng, WANG Wenming, HAN Xinqiang Journal of General Surgery for Clinicians    2022, 10 (4): 34-.   Abstract （28）            Knowledge map    Save Hepatocellular carcinoma (HCC) is one of the six most common malignant tumours globally. Early diagnosis and timely surgical resection can maximise the benefits for patients. However, based on the unique pathophysiological characteristics of the liver, most patients have been in the advanced stage of the tumour at the initial diagnosis and lost the opportunity of surgical resection; transcatheter arterial chemoembolisation (TACE) is its definitive treatment, but HCC patients with portal vein tumor thrombus (PVTT) are relatively contraindicated to TACE treatment. Hepatic artery infusion chemotherapy (HAIC) using the characteristics of liver first-pass effect, continuous high-concentration infusion of chemotherapeutic drugs directly into tumour blood supply arteries has made remarkable achievements in middle and advanced HCC in recent years. However, there is no unified diagnosis and treatment standard and specification for HAIC. This paper reviews the clinical application of HAIC in advanced HCC. Related Articles | Metrics