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Table of Content

    01 January 2021, Volume 9 Issue 1
    Laparoscopic total extraperitoneal hernia repair for the treatment of inguinal hernia with different fixation methods
    HUANG Jianfeng, SUN Zhenzhi, LIU Yuhui, WANG Tao, JIN Jitao, NIE Yong
    2021, 9(1):  3. 
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    The application value of artificial intelligence computer aided system in benign and malignant thyroid nodules
    YANG Xiaoyun, TIAN Ye, ZHANG Wei, JIANG Jue, WANG Juan, ZHOU Qi
    2021, 9(1):  12. 
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    Abstract: Objective To explore the diagnostic value of artificial intelligence computer aided system (AI-CAD) in benign and malignant thyroid nodules. Methods To analyzed 473 patients with 517 thyroid nodule in Xi 'an Jiaotong University the second affiliated hospital from June 2019 to December 2019, all nodules were confirmed by pathology, based on AI-CAD, the judgment standard is divided into three groups, the AI score of benign group was 0~0.40, the AI score of suspicious group score was
    0.41~0.60 and the AI score of malignant group was 0.61~1.00. The distribution of scores in each group was observed by boxplot, and the diagnostic accuracy was compared among the three groups with pathological results as the gold standard. Results The diagnostic accuracy rates of benign and malignant thyroid nodules were respectively 88.94%, 69.75% and 84.53%. There was significant difference between groups (P<0.001). Conclusion Artificial intelligence assisted system has high value for the differential diagnosis of benign and malignant thyroid nodules, especially for the determination of benign nodules, which is beneficial to help beginners to improve their confidence in diagnosis.

    Research on the relationship between self-compassion and resilience in chronic pain patients
    MENG Jing, LI Yang, LIU Yu, CHEN Jing
    2021, 9(1):  16. 
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    Abstract: Objective To explore the correlation between self-compassion and psychological elasticity in patients with chronic pain, provide a theoretical basis for the clinical development of psychological intervention programs. Methods This study uses the General Information Questionnaire, Self-Compassion Scale and psychological resilience. A survey was conducted on 195 chronic pain patients in Qingdao Municipal Hospital, the influencing factors and correlation between self compassion and resilience in patients with chronic pain were analyzed. Results The total score of self-compassion for chronic pain patients was (53.12±8.59) points, and the total score of psychological elasticity was (58.65±16.31) points. There is a positive correlation between self-compassion and psychological resilience in patients with chronic pain,with a correlation coefficient of 0.415; Multiple linear regression analysis showed that the cultural level and gender of patients with chronic pain were the main factors affecting
    patients’ Self-compassion(P<0.05). Conclusion By adjusting the level of psychological resilience of chronic pain patients can be improved psychological defense, and reduce psychological stress.
    Clinicopathological characteristics and prognosis of invasive ductal/lobular mixed carcinoma, invasive lobular carcinoma and invasive ductal carcinoma of breast
    LENG Minfang, CHENG Wende, XIAO Xiaoqin, LIU Feng
    2021, 9(1):  24. 
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    Abstracts: Objective To study the pathological characteristics of breast infiltrative ductal / lobular mixed carcinoma(IDC-L), infiltrative lobular carcinoma(ILC) and infiltrative ductal carcinoma(IDC). Methods From September 2011 to September 2020,254 breast cancer patients were selected, Among them, there were 18 cases of IDC-L, 20 cases of ILC and 216 cases of IDC. The prognosis of the three groups of patients was observed. Results IDC- L, ILC and IDC patients had significant differences in age, tumor size, multicentric lesions, vascular invasion, HER2 status, Ki-67 expression. IDC-L patients had younger onset age, more tumor diameter>2.0 cm, while IDC patients had less multicentric lesions and vascular invasion, while HER2 positive rate and Ki-67 high expression ratio in IDC-L and ILC patients were lower than IDC, the difference was statistically significant(P<0.05). Age, climacteric state, tumor size, lymph node state, multicentric lesions, lymphatic vessel invasion, HER2 state and Ki-67 expression were all the influencing factors of clinic pathological differences. Breast cancer-free interval and overall survival were related to tumor size, lymph node status, lymphatic vessel invasion and Ki-67 expression (P<0.05). Conclusion In breast cancer patients, the clinicopathological characteristics of ILC and IDC-L are similar to each other, but there are obvious differences among ILC, IDC-L and IDC. The breast cancer patients can be differentiated clinically and treated better.

    Endoscopic retrograde appendicitis treatment for acute uncomplicated appendicitis: therapeutic effect and safety evaluation
    LI Xin
    2021, 9(1):  31. 
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    Abstract: Objective To analyze the efficacy and safety of endoscopic retrograde appendicitis treatment for acute uncomplicated appendicitis. Methods The subjects of this study were 80 patients with acute uncomplicated appendicitis admitted to Foshan Women and Children Hospital from July 2018 to May 2020. They were divided into conventional groups (laparoscopic appendectomy) according to different treatment methods. Study group (retrograde endoscopic appendicitis treatment), 40 cases in
    each group. Compare the levels of serum tumor necrosis factor (TNF-α), C-reactive protein (CRP), and interleukin (IL) -6 before and after treatment in the two groups, as well as the time in bed, hospitalization time, operation time, and incidence of complications , To explore the efficacy and safety of endoscopic retrograde appendicitis treatment. Results Before treatment, the levels of TNF-α, CRP and IL-6 of the two groups were not statistically different (P>0.05). After treatment, the levels of TNF-α, CRP,
    and IL-6 in the study group were lower than those in the conventional group (P<0.05); the bed time, hospital stay, and operation time of the study group were shorter than those in the conventional group (P<0.05); The complication rate of the group was 2.50%, which was lower than that of the conventional group (15.00%,P<0.05). Conclusion The use of endoscopic retrograde appendicitis treatment for acute uncomplicated appendicitis is less invasive, can reduce surgical stress response, is very conducive to the rapid recovery of patients after surgery, and has good safety.

    Effect of dexmedetomidine combined with ropivacaine transverse abdominis plane block on elderly patients undergoing radical resection of colorectal cancer
    LI Chaoyang, HUANG Zhidong, YANG Jixiong
    2021, 9(1):  35. 
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    Abstract: Objective To investigate the effect of dexmedetomidine combined with ropivacaine transverse abdominis plane block on elderly patients undergoing radical resection of colorectal cancer. Methods From July 2018 to July 2020, 64 patients with colorectal cancer who underwent radical surgery in the Second Affiliated Hospital of Guangdong Medical University were selected as the
    research objects and randomly divided into study group and control group, 32 cases in each group, The control group was given ropivacaine transversus abdominis plane block, and the study group was given dexmedetomidine on the basis of the control group. The operation recovery of the two groups were compared, including extubation cases, respiratory recovery time, rescue analgesia, recovery time, intraoperative blood loss, extubation time; the condition recovery, including eating time, hospitalization time, postoperative first exhaust time, first out of bed time, defecation time. The degree of postoperative pain was evaluated by visual analogue scale. The levels of immunoglobulin (Ig)G, IgA and IgM were detected by immunoturbidimetric method. The postoperative recovery quality scale was used to evaluate the recovery status of patients, and the incidence of arrhythmia, blood pressure drop, nausea, vomiting, headache, dizziness and other complications were compared between the two groups. Results There was no significant difference in intraoperative blood loss, extubation time, and extubation cases between the two groups (P>0.05). The rescue analgesia rate, respiratory recovery time and recovery time of the study group were less than those of the control group (P<0.05); At 2h, 6h, 12h and 24h after operation, the scores of visual analogue at cough and rest in the control group were higher than those in the study group, with significant difference (P<0.05); Before operation, there was no significant difference in IgM, IgG and IgA between the two groups (P>0.05); After operation, IgM, IgG and IgA in the two groups were increased, and those in the study group were higher than those in the control group, with significant difference (P<0.05); The time of getting out of bed for the first time, defecation time, postoperative first exhaust time and hospitalization time of the study group were less than those of the control group, with significant difference (P<0.05); There was no significant difference in the score of recovery quality scale between the two groups on the first day before operation (P>0.05); On the third day after operation,
    the scores of physical comfort, total score of recovery quality scale, psychological support, pain and emotional state of the study group were higher than those of the control group In the control group, the difference was significant (P<0.05); The incidence of nausea, vomiting, headache and dizziness in the study group was lower than that in the control group, the difference was significant (P<0.05), and there was no significant difference in the incidence of arrhythmia and blood pressure drop between the two groups (P>0.05). Conclusion Dexmedetomidine combined with ropivacaine transversus abdominis plane block can significantly improve the analgesic effect of elderly patients with colorectal cancer radical operation, enhance the immune ability of patients, improve the motor and gastrointestinal function of patients, and improve the quality of recovery.
    Analysis of misdiagnosis of 6 cases of acute appendicitis with secondary perirenal abscess
    YU Anxing, DAI Xueqiang
    2021, 9(1):  43. 
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    Abstract: Objective To explore the main causes of misdiagnosis of acute appendicitis with secondary perirenal abscess and the measures to avoid misdiagnosis. Methods A retrospective analysis of laboratory results and surgery was made on 6 cases of acute appendicitis with secondary perirenal abscess misdiagnosed in Pingdu People’s Hospital Affiliated to Weifang Medical College. Results One case was performed laparotomy and one case was performed laparoscopy. The two cases were proved to be secondary perirenal abscess of post-cecal gangrenous appendicitis. The other 4 cases were diagnosed by multi-slice computed tomography (MSCT), one of which was improved after puncture and drainage, 1 case underwent right nephrectomy, and 2 cases died of Septicemia and multi-system organ failure due to delayed diagnosis and treatment. Conclusion The cause of misdiagnosis of acute appendicitis with secondary perirenal abscess is the nonspecific symptoms. To avoid misdiagnosis, the abdomen should be examined by MSCT.

    Effect of Qudu Decoction fumigation on postoperative inflammatory factors and recovery in patients with perianal abscess and type 2 diabetes mellitus 
    LI Yan
    2021, 9(1):  46. 
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    Abstract: Objective To observe the effect of Qudu Decoction fumigation on postoperative inflammatory factors and recovery in patients with perianal abscess and type 2 diabetes mellitus. Methods: 106 patients with perianal abscess complicated with type 2 diabetes mellitus in Taiyuan Central Hospital from August 2017 to October 2019 were selected and divided into observation group (n=53) and control group (n=53) by digital table method. All patients were scheduled to complete onetime thread drawing drainage. On the basis of routine nursing, the control group was given sitz bath with potassium permanganate solution, and the observation group was fumigated with Qudu Decoction once

    every day. Two weeks later, the curative effect, difficulty of first defecation, wound healing time, serum inflammatory factors and complications of the two groups were compared. Results There was significant difference in the total effective rate of traditional chinese medicine syndrome between the two groups (P<0.05); the wound healing time of the observation group was significantly less than that of the control group (P<0.05), and the serum inflammatory factor level of the observation group was significantly lower than that of the control Group on the 7th day after operation (P<0.05). Conclusion Hip bath with Qudu decoction can effectively relieve pain, inhibit the expression of inflammatory factors, accelerate wound healing, reduce the incidence of complications and achieve satisfactory curative effect in patients with perianal abscess and type 2 diabetes mellitus. It is a characteristic diagnosis and treatment scheme of integrated traditional Chinese and Western medicine.

    Research application of perioperative management of stands for enhanced recovery after surgery in patients undergoing laparoscopic appendectomy
    ZHONG Xuemei, ZHANG Peiting, WANG Yuxin
    2021, 9(1):  51. 
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    Abstract:Objective To explore the clinical effect of stands for enhanced recovery after surgery (ERAS) in the operating room in patients with laparoscopic appendectomy. Methods We selected 100 patients with laparoscopic appendectomy in John Wan Hospital from January 2019 to August 2020 as the research objects. Using random number method, they were divided into 50 cases in the control group (conventional perioperative management) and 50 cases in the observation group (perioperative

    management based on the concept of ERAS). The postoperative exhaust time, first meal time, first activity time and total hospital stay, the numerical rating scale (NRS) scores at 6h, 12h and 24h after operation, activity of daily living(ADL) scores before and 3 days after operation and the incidence ofpostoperative complications were compared between the two groups. Results The postoperative exhaust time, first meal time, first activity time and total hospital stay in the observation group were significantly 

    lower than those in the control group (P<0.01); The NRS of the observation group at 6h and 12h after operation were significantly lower than those of the control group (P<0.01), and there was no significant difference in the scores of the two groups at 24h after operation (P>0.05); There was no significant difference in ADL scores between the two groups before surgery (P>0.05), and the ADL scores of the observation group were higher than those of the control group on the 3rd day after surgery (P<0.01); The

    incidence of complications such as wound infection, bleeding, nausea and vomiting and diarrhea in the observation group was significantly lower than that in the control group (χ2=8.31, P<0.01). Conclusion Based on the perioperative management of ERAS, it can effectively reduce the patient’s perioperative stress response, reduce the incidence of complications, promote postoperative recovery, and shorten the length of hospitalization.

    Qualitative study on the characteristics of dietary behavior and management of patients with short bowel syndrome
    SHEN Ruting, LUO Juan, HUANG Yingchun, YE Xianghong
    2021, 9(1):  56. 
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    To deeply understand the dietary behavior characteristics and self dietary management experience of patients with short bowel syndrome, so as to further guide and intervene the dietary management of patients and improve the compliance of dietary management. Methods Face to face and semi-structured interviews were conducted in 15 patients with short bowel syndrome by

    using qualitative research phenomenological method. The interview data were analyzed by Colaizzi phenomenological data analysis method. Results There were four aspects of experience in the dietary behavior characteristics and management of patients with short bowel syndrome: daily dietary structure change, dietary guidance information acquisition and cognition, self dietary management types, dietary management support needs. Conclusion In the future work, medical staff should pay attention to the

    improvement of the cognition of disease and diet knowledge of patients with short bowel syndrome. Multi mode diet guidance can be used to improve the knowledge reserve of patients, and the diet compliance can be improved by making scientific and quantitative diet plan. At the same time, it should be pay attention to the family and social support of patients to ensure their normal social function.