Abstract:

Objective To explore the sensitivity of high-resolution magnetic resonance imaging (MRI) in the preoperative T staging assessment of locally advanced rectal cancer. Method A total of 86 patients with locally advanced rectal cancer who underwent preoperative high-resolution MRI staging at the First Hospital of Hohhot from February 2024 to January 2025 were included and compared with the postoperative pathological results. The sensitivity, specificity rate, accuracy rate, positive predictive rate, negative predictive rate and Kappa value were calculated to evaluate the accuracy and consistency of high-resolution MRI in diagnosing T staging. The receiver operating characteristic (ROC) curve was plotted and the area under the curve (AUC) was calculated. Result Among the 86 patients with locally advanced rectal cancer, 76 cases had the same high-resolution MRI and pathological stage. The overall diagnostic accuracy rate was 88.37%, and the Kappa value was 0.842, showing a high degree of consistency with the postoperative pathology. High-resolution MRI had the highest diagnostic sensitivity (92.86%) in stage T3, but its specificity was relatively low (80.00%). The sensitivity of stage T4 was 82.61%, the specificity was 95.24%, and the accuracy rate was 91.86%. The specificity of stage T1~2 reached 98.73% and the accuracy rate was 96.51%. ROC curve analysis showed that the AUC of MRI in diagnosing T1~2 stage, T3 stage and T4 stage was 0.851, 0.865 and 0.889 respectively, all of which had high discriminative ability. Conclusion High-resolution MRI has good diagnostic efficacy in the preoperative T staging assessment of locally advanced rectal cancer, especially showing high sensitivity and accuracy in the identifi cation of T3 and T4 stages.

Key words: High-resolution, Magnetic resonance imaging, Advanced rectal cancer, T staging