Abstract:

Objective To investigate the risk factors of lymph node metastasis in the central region of cN0 thyroid micropapillary carcinoma. Method The clinical data of 106 patients with cN0 thyroid micropapillary carcinoma in Jiangmen Xinhui District People's Hospital from May 2020 to November 2021 were retrospectively analyzed. According to the lymph node metastasis in the central region, they were divided into two groups: metastatic group (49 cases) and non-metastatic group (57 cases). The risk factors of lymph node metastasis in the central region of patients were analyzed. Result Of the 106 patients, 49 had lymph node metastasis in the central region and 57 had no metastasis. The proportion of males, tumor location, microcalcification and invasion of capsule

in the metastatic group was higher than that in the non-metastatic group (P ＜ 0.05), the proportion of patients with age ＜ 55 years old and tumor diameter ＜ 5 mm was lower than those without metastasis (P ＜ 0.05), however, there was no significant difference in the proportion of patients with nodular goiter and Hashimoto's thyroiditis between the two groups (P ＞ 0.05). Multivariate logistic regression analysis showed that the risk factors of lymph node metastasis in the central region of 106 patients included male, microcalcification and capsule invasion (P ＜ 0.05). Conclusion The risk factors of lymph node metastasis in the central region of cN0 thyroid micropapillary carcinoma include male, microcalcification, and invasion of capsule. Preventive and therapeutic dissection of lymph nodes in the central region is recommended.

Key words: Thyroid micropapillary carcinoma, Central lymph node metastasis, Risk factors