Abstract:

Objective To investigate the effect of laparoscopic cholecystectomy on stress response indicators in patients with gallstones. Method 78 patients with gallstones who were treated in Jurong People's Hospital from January 2020 to March 2022 were divided into control group (39 cases) and observation group (39 cases) according to random number table. The changes of stress indexes were observed before and after surgery in the two groups. The recovery time of gastrointestinal function and comparing the changes of gastrointestinal hormone levels were also observed. Result The levels of endothelin and cortisol in the

observation group were significantly lower than those in the control group, and the levels of serum superoxide dismutase were higher than those in the control group (P ＜ 0.05). The postoperative recovery time of patients in the observation group was shorter than that in the control group, and the monitoring concentrations of motilin and gastrin were higher than those in the control group, with significant differences (P ＜ 0.05). Conclusion Laparoscopic cholecystectomy for patients with gallstones can effectively reduce postoperative stress response and promote the recovery of gastrointestinal function.

Key words: Laparoscopic cholecystectomy, Gallstones, Stress response, Gastrointestinal function