Abstract:

Objective To investigate the related factors of hypoparathyroidism after thyroidectomy. Method The clinical data of 150 patients who underwent thyroidectomy in Wuhan Xinzhou District People's Hospital from January 2018 to March 2020 were analyzed retrospectively. According to whether there was hypoparathyroidism after operation, they were divided into hypoparathyroidism group (29 cases) and normal function group (121 cases). The incidence of hypoparathyroidism after thyroidectomy was counted, the clinical data of patients with hypoparathyroidism and normal function were compared, and the risk factors of hypoparathyroidism after thyroidectomy were analyzed. Result There were 29 cases (19.33%) of hypoparathyroidism in 150 patients after thyroidectomy. Thyroid capsule invasion, lymph node dissection, parathyroid MIS resection, tumor diameter ＞4cm, no nano carbon tracer and open operation were the risk factors of parathyroid dysfunction after thyroidectomy (OR=3.963,3.658,3.281,3.357,3.943,4.187,P ＜ 0.05). Conclusion Patients with hypoparathyroidism after thyroidectomy have a high probability of hypoparathyroidism. The risk factors of hypoparathyroidism include thyroid capsule invasion, lymph node dissection, parathyroid MIS resection, tumor diameter ＞ 4cm, no application of nano carbon tracer and open surgery. According to this, clinical patients can be given targeted treatment and intervention measures after thyroidectomy, to reduce the risk of hypoparathyroidism.

Key words: Thyroidectomy, Hypoparathyroidism, Risk factors