Abstract:

Objective To compare the clinical efficacy and postoperative complications of traditional laparotomy and laparoscopic surgery in patients with colorectal cancer. Method A total of 60 patients with colorectal cancer admitted to our hospital from January 2018 to September 2021 were selected as the research subjects, and were divided into traditional open surgery group (control group) and laparoscopic surgery group (observation group) by different surgical methods, with 30 patients in each group. The clinical treatment effects of the two groups were compared, and the oxidative stress level and postoperative complications were compared before and 3 days after surgery. Result The amount of intraoperative bleeding in the observation group was (70.35±23.32)ml, which was less than that in the control group (164.83±43.24)ml. The operation time was (146.48±15.34)

min, the recovery time of intestinal function was (60.35±13.43)h and the hospital stay was (11.83±5.32)d, which were shorter than those in the control group (P ＜ 0.05). Before treatment, there was no significant difference in the levels of superoxide dismutase(SOD) and serum malondialdehyde(MDA) between the two groups (P ＞ 0.05); after treatment, the levels of SOD and MDA in the observation group were (85.30±12.99)kU/L and (6.01±1.83)mmol/L respectively, and those in the control group were (74.81±11.23)kU/L and (7.29±1.92)mmol/L respectively (P ＜ 0.05). The total incidence of complications in the observation group was lower than that in the control group (P ＜ 0.05). Conclusion Laparoscopic surgery is better than open surgery in the treatment of colorectal cancer, the patients have less trauma, rapid recovery and high safety.

Key words: Colorectal cancer, Laparoscope, Open operation, Curative effect