Abstract:

Objective To investigate the anesthetic effect of remifentanil combined with propofol in laparoscopic cholecystectomy. Method 88 patients who underwent laparoscopic cholecystectomy in Liyang branch of Jiangsu Provincial People's Hospital from July 2020 to July 2021 were selected, they were randomly divided into control group (44 cases, anesthesia with propofol) and observation group (44 cases, anesthesia with remifentanil combined with propofol). The anesthesia recovery effect, adverse

reactions, systolic blood pressure, diastolic blood pressure, heart rate level before and after operation and the score of Mini Mental State Examination (MMSE) were compared between the two groups. Result Compared with the control group, the recovery of orientation, consciousness, extubation and spontaneous breathing in the observation group were shorter, The visual analogue score was lower (P ＜ 0.05). After operation, the levels of systolic blood pressure, diastolic blood pressure and heart rate in the observation group were better than those in the control group (P ＜ 0.05). At 1h and 24h after extubating, the MMSE score in the observation group was higher than that in the control group (P ＜ 0.05). Compared with the incidence of adverse reactions in the control group (13.64%), the incidence of complications in the observation group (2.27%) was lower. Conclusion Remifentanil combined with propofol anesthesia is effective in laparoscopic cholecystectomy, which can shorten the recovery time of patients, has little impact on hemodynamics, is conducive to the recovery of cognitive function and reduce the occurrence of adverse reactions.

Key words: Remifentanil, Propofol, Laparoscopic cholecystectomy, Anesthetic effect