Abstract:

Objective To evaluate the predictive value of barium enema in the diagnosis of congenital megacolon. Method The clinical data of 107 infants admitted to the Children’s Hospital of Suzhou University from July 2015 to December 2019 were analyzed retrospectively, the patients were divided into case group and control group according to pathological results. The results were compared between case group and control group.Receiver operator characteristic curve ROC curve, analysis was used to determine the diagnostic ability of the relevant factors. Result Among the 107 children, 51 cases of congenital megacolon(case group) were diagnosed (41 males and 10 females). In univariate analysis, the results of vomiting, abdominal distention, delayed meconium excretion, barium enema and digital rectal examination were significantly compared between the two groups. Multivariate regression analysis showed that the results of barium enema (95%CI 11.718 ～ 999.99) were independent factors affecting congenital megacolon. The area under the ROC curve of barium enema in the diagnosis of neonatal congenital megacolon was 0.949, the diagnostic sensitivity was 92.2%, and the specificity was 94.6%. Conclusion Abdominal distension, vomiting, no meconium excretion in 24 hours, gas in intestinal cavity and bursting sensation after digital rectal examination are relevant factors in the diagnosis of congenita megacolon, and barium enema is an independent factor in the diagnosis of neonatal congenital megacolon. 

Key words: Congenital megacolon, Barium enema, Neonate