Abstract:

Objective To investigate the efficacy of endoscope combined with drugs in the diagnosis

and treatment of esophageal and gastric variceal bleeding in liver cirrhosis and the influencing factors

of rebleeding. Methods From February 2019 to February 2021, 80 patients with esophageal and gastric

varices rupture and bleeding of liver cirrhosis treated in Shenzhen Integrated Traditional Chinese

and Western Medicine Hospital were selected. All patients were treated with endoscopic esophageal

varices ligation combined with endoscopic varices sclerotherapy injection. They were divided into

recurrent group (n=22) and non-recurrent group (n=58) according to whether there was rebleeding after

operation, to analyze the efficacy of endoscopy combined with drugs in the treatment of esophageal and

gastric variceal bleeding in liver cirrhosis and the risk factors of rebleeding. Results All patients were

successfully hemostatic, and the success rate of hemostasis was 100.00%; There was no significant

difference in gender, age, portal vein diameter, Child-Pugh score, albumin concentration and blood

sodium level between recurrent group and non-recurrent group (P＞0.05); Portal vein diameter and Child-Pugh score were the risk factors of rebleeding after endoscopic combined with drug treatment of

esophageal and gastric varices bleeding in liver cirrhosis (P＜0.05). Conclusion Endoscope combined

with drugs is effective in the diagnosis and treatment of esophageal and gastric variceal bleeding in liver

cirrhosis. The risk factors of rebleeding after esophageal and gastric variceal bleeding in liver cirrhosis

include portal vein diameter and Child-Pugh score.

Key words: Liver cirrhosis, Esophageal and gastric varices, Bleeding, Endoscope, Factor