Abstract:

Objective To investigate the clinical efficacy and safety of endoscopic retrograde acute

appendicitis with peripheral abscess formation, and to provide reference basis for clinical treatment.

Methods 86 patients with acute appendicitis with peripheral abscess treated in Dazhou integrated

traditional Chinese and Western medicine hospital from June 2018 to June 2020 were randomly divided

into study group and control group, with 43 cases in each group. The study group was treated with

endoscopic retrograde appendicitis therapy (ERAT), and the control group was treated with laparoscopic

appendectomy (LA). The total effective rate, the incidence of complications 2 weeks after operation and the levels of inflammatory factors (C-reactive protein, interleukin-6 and interleukin-8) before and

1 week after operation were compared between the two groups. Results After one week of treatment,

the total effective rate in the study group was 95.35% (41/43), which was significantly higher than

83.72% (36/41) in the control group (P ＜ 0.05). Before treatment, there was no significant difference in

C-reactive protein, interleukin-6 and interleukin-8 between the two groups (P ＞ 0.05); After one week of

treatment, C-reactive protein, interleukin-6 and interleukin-8 in the study group were significantly lower

than those in the control group (P ＜ 0.05). Two weeks after operation, the incidence of postoperative

complications in the study group was 4.65% (2/43), lower than 13.95% (6/43) in the control group (P

＜ 0.05). Conclusion Endoscopic retrograde surgery for patients with acute appendicitis with peripheral

abscess can reduce the level of inflammatory factors, reduce postoperative complications and improve the

curative effect.

Key words: Endoscopy, Acute appendicitis, Periappendiceal abscess formation