Abstract:

Objective To study the effect of time of laparoscopic cholecystectomy (LC) performed after percutaneous transhepatic gallbladder drainage (PTGD) in patients with acute calculous cholecystitis (ACC) on the fi nal outcome. Method Retrospective analysis of clinical data of 80 ACC patients admitted to Tongzhou District Traditional Chinese Medicine Hospital in Beijing from January 2021 to December 2022, all patients underwent LC treatment after PTGD. According to the interval time of LC after PTGD, patients were divided into experimental group ( ＞ 60 days) and control group ( ≤ 60 days), and the surgical effi cacy of the two groups was compared.Result The thickness of the gallbladder wall before LC in the experimental group was thinner than that in the control group, and the time for LC surgery and postoperative hospitalization were shorter than those in the control group. The amount of bleeding during LC surgery was less than that in the control group, and the rate of conversion to open surgery and postoperative complications were lower than those in the control group, with significant diff erences (P ＜ 0.05). The levels of  adrenocorticotropic hormone (ACTH) in the experimental group after LC were signifi cantly lower than those in the control group (P ＜ 0.05). Conclusion Patients with ACC treated with LC 60 d after PTGD had better surgical performance, shorter surgical time, etc. while also improving intraoperative and postoperative safety and reducing patient stress.

Key words: Acute calculous cholecystitis, Percutaneous transhepatic gallbladder drainage, Laparoscopic cholecystectomy, Surgical intervals