Abstract:

Objective To analyze the impact of laparoscopic radical resection of colorectal cancer on liver and kidney function in patients. Method 120 patients with colorectal cancer who received treatment at Rong’an County People’s Hospital in Liuzhou City from March 2021 to March 2023 were selected and randomly divided into a control group and an experimental group (each with 60 cases) using a random number table method. The control group received traditional open surgery, while the experimental group received laparoscopic radical resection for colorectal cancer. The liver and kidney function indicators and postoperative complications of the two groups of patients were compared. Result On the fi rst day before surgery, there was no signifi cant diff erence in liver and kidney function indicators between the two groups of patients (P ＞ 0.05). Three days after surgery, the lactate dehydrogenase levels in the experimental group patients increased signifi cantly compared to the fi rst day before surgery (P ＜ 0.05); The total protein, cholinesterase, and albumin levels of the experimental group patients were signifi cantly lower than those of the control group, and the uric acid level was signifi cantly lower than that of the control group, with signifi cant diff erences (P ＜ 0.05). The incidence of postoperative complications in the experimental group was signifi cantly lower than that in the control group (5.00% vs. 16.67%; P=0.040). Conclusion Laparoscopic radical surgery for colorectal cancer can impose a burden on the liver function of patients and have a smaller impact on their renal function. Compared to traditional open surgery, the risk of complications is lower.

Key words: Colorectal cancer, Laparoscopic radical surgery, Liver and kidney function, Complications