Abstract:

Objective To investigate the effect of laparoscopic radical resection of right colon cancer on the recovery of gastrointestinal function in patients with colon cancer. Method 66 patients with colon cancer admitted to Suzhou Municipal Hospital from January 2020 to December 2021 were selected and divided into observation group and control group with 33 cases in each group according to the results of blue-green ball lottery. The patients in the control group were treated with open radical resection of right colon cancer, and the patients in the observation group were treated with laparoscopic radical resection of right colon cancer. The postoperative recovery of the two groups were recorded and compared, and the changes of gastrointestinal function and immune function indexes before and after operation and the occurrence of postoperative complications were compared between the two groups. Result The recovery of bowel sounds, exhaust, defecation and hospital stay in the observation group were significantly shorter than those in the control group (P ＜ 0.05). There was no significant difference in preoperative gastrointestinal function and immune function between the two groups (P ＞ 0.05); the levels of

motilin and gastrin in the observation group were higher than those in the control group, CD4+ T cell was higher than that in the control group, and CD8+ T cell was lower than that in the control group (P ＜ 0.05). In addition, the total incidence of postoperative complications in the observation group was lower than that in the control group (P＜ 0.05). Conclusion Laparoscopic radical resection of right colon cancer can effectively promote the postoperative recovery of patients with colon cancer, with little impact on gastrointestinal function, less complications and ideal safety.

Key words: Laparoscopic radical resection of right colon cancer, Colon cancer, Gastrointestinal function, Immunologic function