Abstract:

Objective To investigate the efficacy of laparoscopic left hemi hepatectomy via middle hepatic vein approach in the treatment of intrahepatic bile duct stones and its effect on stress and inflammatory response. Method 80 patients with intrahepatic bile duct stones treated in Taizhou People's Hospital from January 2019 to January 2022 were randomly divided into control group (conventional laparoscopic left hemi hepatectomy, n=40) and observation group (laparoscopic left hemi hepatectomy via middle hepatic vein, n=40). The related indexes of the two groups were compared, and the preoperative and postoperative cortisol, serum The levels of C-reactive protein and interleukin-6 were used to evaluate the state of stress and inflammation, and the incidence of complications in the two groups was statistically analyzed. Result All the patients in the two groups successfully completed the operation. There was no significant difference between the two groups in operation time, bleeding volume, time

out of bed, exhaust time and hospital stay (P ＞ 0.05). The levels of cortisol, C-reactive protein and interleukin-6 in the observation group were lower than those in the control group (P ＜ 0.05), and the incidence of complications was lower than that in the control group (P ＜ 0.05). Conclusion Laparoscopic left hemi hepatectomy through the middle hepatic vein is safe and effective in the treatment of intrahepatic bile duct stones, which can reduce stress and inflammatory reaction, and reduce the risk of complications.

Key words: Intrahepatic bile duct stones, Middle hepatic vein approach, laparoscope, Left hemi hepatectomy, Complication