Abstract:

Objective To investigate biomarks and ultrasonic doppler in the diagnosis and management of early hepatic artery thrombosis after liver transplantation Method One patient with early hepatic artery thrombosis after liver transplantation successfully underwent vascular reconstruction and intravascular interventional therapy. The changes of biochemical indexes and color doppler ultrasound during the treatment were analyzed retrospectively. Combined with the relevant literature at home and abroad, the changes of biochemical indexes and color Doppler ultrasound during the treatment of early hepatic artery thrombosis after liver transplantation were summarized. Result The patient developed hepatic artery thrombosis, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase γ-Glutamyl transpeptidase increased significantly, among which γ-Glutamyl transpeptidase began to increase as early as 3 days before the diagnosis of thrombosis. Cholinesterase decreased after hepatic artery thrombosis. The changes of the above biochemical indexes reached the peak on the second day after blood flow recovery, and began to decline on the third day after blood flow recovery. Doppler ultrasound could detect that the velocity of portal vein increased significantly 3 days before thrombosis. Conclusion Early hepatic artery thrombosis after liver transplantation should been considered when γ-Glutamyl transpeptidase was rising and/or the inspection and measurement of biomarks and Subsequent ultrasonic doppler showed that the velocity of portal vein was rising.

Key words: Liver transplantation, Hepatic artery, Thrombosis, Biomarks, Ultrasonic doppler