Abstract:

Objective To investigate the effects of modified thoracic nerve block combined with general anesthesia on blood flow parameters and complications in patients undergoing radical mastectomy of breast cancer. Method A total of 80 patients undergoing radical mastectomy of breast cancer in our hospital from February 2018 to December 2020 were selected as the research subjects, and they were divided into routine group and study group by random number table method, with 40 cases in each group. The conventional group was treated with general anesthesia, while the study group was treated with modified thoracic nerve block combined with general anesthesia. The hemodynamic parameters, intraoperative sufentanil dosage, time of recovery and incidence of complications were compared between the two groups at before anesthesia (T0), before intubation (T1), during intubation (T2) and extubation (T3). Result At T1, T2 and T3, the fluctuation range of diastolic blood pressure, systolic blood pressure and heart rate in the study group were lower than those in the control group (P ＜ 0.05). Meanwhile, the recovery

time of sufentanil in the study group was shorter than that in the conventional group (P ＜ 0.05). The incidence of complications in the study group (5.00%) was lower than that in the conventional group (20.00%) (P ＜ 0.05). Conclusion Modified chest nerve block combined with general anesthesia in radical mastectomy of breast cancer can effectively stabilize the hemodynamic parameters of patients, reduce their intraoperative sufentanil, shorten the recovery time and reduce the incidence of complications.

Key words: Radical mastectomy of breast cancer, Modified thoracic nerve block, General anesthesia, Blood flow parameters, Complications