Abstract:

Abstract： Objective To evaluate the prognostic value of patients with vascular infiltration after radical gastrectomy for gastric cancer. Methods The clinical data of 303 patients (129 with vascular infiltration and 174 without vascular infiltration) who underwent radical gastrectomy in Wenshang County People's Hospital from January 2003 to June 2015 were analyzed retrospectively. To compare the differences of clinicopathological features and prognosis between patients with positive and negative vascular infiltration. Results There were significant differences in tumor size, pT stage, pN stage and tissue differentiation between the positive and negative groups of vascular infiltration (P<0.05). There was no significant difference in age and gender (P>0.05). Univariate survival analysis showed that the 5-year survival rate of patients with vascular infiltration was 33.3%(43/129), and that of patients without vascular infiltration was 56.9%(99/174), and the difference was statistically significant (P<0.001). Multivariate survival analysis showed that vascular invasion and pN stage were independent risk factors affecting the prognosis of gastric cancer patients. Conclusion Vascular infiltration is an independent risk factor affecting the prognosis of gastric cancer patients.

Key words: Gastric cancer, Vascular infiltration, Prognosis