Abstract:

Objective To investigate the gastrointestinal function of chewing gum after laparoscopic resection of left colon cancer and explore its mechanism of action. Methods 65 patients underwent laparoscopic resection of left colon cancer were selected in the department of general surgery between January 2018 to September 2020 in Nongken Central Hospital. These patients were divided into research group (n=35) and control group (n=30). The patients in the research group chewed 2 pieces of xylitol gum three times daily for 30 minutes after surgery, while control group received traditional managements. The levels of procalcitonin (PCT) and C reactive protein (CRP) were examined with peripheral blood on day 1 and 3 after operation. Postoperative exhaust and defecation time, postoperative

hospital stays and postoperative inflammatory factor level of the two groups was compared. Results All the 65 patients recovered and were discharged smoothly, and the postoperative exhaust and defecation time and postoperative hospitalization days in the research group were shorter than those in the control group (P<0.05). The levels of inflammatory factors in postoperative day 1 and day 3, PCT and CRP were lower than the control group(P<0.05). Conclusions Chewing gum after laparoscopic resection of the left colon cancer can promote the early recovery of gastrointestinal function, and its mechanism may inhibit the release of inflammatory factors and promote gastrointestinal motility.

Key words: Chewing gum, Laparoscopic resection of the left colon cancer, Gastrointestinal function