临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (3): 159-.

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早期检测D- 二聚体对下肢深静脉血栓形成诊断的影响

  

  1. 同济大学附属东方医院胶州医院 检验科,山东 青岛 266300
  • 出版日期:2022-07-01 发布日期:2022-10-25

Effect of early detection of D-dimer on the diagnosis of deep venous thrombosis of lower limbs

  1. Laboratory Department of Jiaozhou Hospital of Dongfang Hospital Affiliated to Tongji University, Shandong Qingdao 266300, China
  • Online:2022-07-01 Published:2022-10-25

摘要:

目的 分析早期检测D- 二聚体对下肢深静脉血栓形成(deep venous thrombosis,DVT)诊断的影响。方法 对同济大学附属东方医院胶州医院2020 年5 月至2021 年12 月收治的DVT 患者52 例(DVT 组)和同期体检健康者52 例(健康组)进行分析,两组对象均行D- 二聚体检测,观察比较两组对象的D- 二聚体检测结果。结果 DVT 组治疗前的D- 二聚体水平显著高于健康组,差异有显著性(P < 0.05);DVT 组经D- 二聚体检测为阳性的有52 例,健康组经D- 二聚体检查为阳性的有51 例,D- 二聚体检测的灵敏度为

98.08%,特异度为100.00%。结论 D- 二聚体检测灵敏性高,特异性较好,能够有效对DVT 早期形成进行预测。

关键词: D- 二聚体, 灵敏性, 特异性, 下肢深静脉血栓形成, 早期

Abstract:

Objective To analyze the effect of early detection of D-dimer on the diagnosis of deep venous thrombosis (DVT). Method 52 patients with DVT (DVT group) and 52 healthy subjects (healthy group) admitted to Jiaozhou Hospital of Dongfang Hospital Affiliated to Tongji University from May 2020 to December 2021 were analyzed. D-dimer detection was performed in both groups, and the results of D-dimer detection were observed and compared between the two groups. Result The level of D-dimer in DVT group was significantly higher than that in healthy group (P < 0.05); in the DVT group, 52 cases were positive for D-dimer, and in the healthy group, 15 cases were positive for D-dimer. The sensitivity and specificity of D-dimer were 98.08% and 100.00%. Conclusion The detection of D-dimer has high sensitivity and specificity, and can effectively predict the early formation of DVT.

Key words: D-dimer, Sensitivity, Specificity, Deep venous thrombosis of lower limbs, Early stage