Abstract:

Objective To explore the application value of modified same-stage endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic cholecystectomy (LC) in the treatment of gallstones with common bile duct stones.Method Sixty patients with gallstones and common bile duct stones admitted to the Department of General Surgery at Rudong Hospital of Traditional Chinese Medicine in Nantong City between January 2023 and December 2024 were enrolled. They were randomly divided into a staged group (30 cases, treated with ERCP followed by LC) and a same-stage group (30 cases, treated with modified same-stage ERCP and LC). Perioperative indicators, biochemical markers, and prognostic outcomes were compared between the two groups. Result There was no significant difference in stone clearance rate between the two groups (P ＞ 0.05). The surgical time, exhaust time, and hospitalization time of patients in the same group were shorter than those in the staging group. The VAS score on postoperative day 3 was lower than that in the staging group, and the total hospitalization cost was lower than that in the staging group. The serum amylase, total bilirubin, total bile acid, C reactive protein, interferon - γ, and interleukin-6 levels on postoperative day 5 were lower than those in the staging group, and the differences were significant (P ＜ 0.05); The quality of life score at 3 months after surgery was higher than that of the staging group (P ＜ 0.05); There was no significant difference in the incidence of complications and stone recurrence between the two groups of patients (P ＞ 0.05). Conclusion Compared to staged ERCP-LC surgery, the modified same-stage ERCP-LC approach offers advantages in shortening recovery time, reducing treatment costs, mitigating infl ammatory responses, and improving prognosis.

Key words: Endoscopic retrograde cholangiopancreatography, Laparoscopic cholecystectomy, Cholecystolithiasis, Common bile duct stones, Quality of life