Abstract:

Objective To investigate the clinical efficacy of laparoscopic holmium laser lithotripsy in the treatment of bile duct stones and its impact on trauma stress indicators. Method 120 patients with bile duct stones admitted to the Fourth People’s Hospital of Chenzhou City from October 2023 to September 2024 were selected as the research subjects. They were randomly divided into an experimental group and a reference group using a random number table method, with 60 patients in each group. The reference group was treated with conventional laparoscopic choledochotomy for stone removal, while the experimental group was treated with laparoscopic holmium laser lithotripsy. Compare the success rate of stone extraction, surgical related indicators, and pre - and post-operative trauma stress indicators between two groups, and observe the complications of the two groups of patients. Result The success rate of stone removal in the experimental group was 96.67% (58/60), which was significantly higher than 83.33% (50/60) in the control group (P=0.015). The operation time, first exhaust time and hospitalization time of the experimental group were shorter than those of the control group, and the intraoperative blood loss of the experimental group was less than that of the control group, with significant differences (P ＜ 0.001). There was no significant difference in the levels of cortisol and epinephrine between the two groups before operation (P ＞ 0.05). One day after operation, the levels of cortisol and epinephrine in the two groups were higher than those before operation, and the levels in the experimental group were lower than those in the control group, with significant differences (P ＜ 0.001). The incidence of complications in the experimental group was 1.67% (1/60), which was significantly lower than 16.67% (10/60) in the control group (P=0.004). Conclusion Laparoscopic holmium laser lithotripsy can improve the success rate of removing bile duct stones, reduce traumatic stress reactions, and minimize complications.

Key words: Laparoscope, Holmium laser lithotripsy, Bile duct stones, Traumatic stress, Liver function