Abstract:

Objective To explore the clinical value of using indocyanine green (ICG) in thyroid cancer surgery. Method 92 patients with papillary thyroid microcarcinoma treated in Dongtai people's Hospital from January 2023 to March 2024 were selected and randomly divided into observation group (n=46) and control group (n=46). All patients underwent unilateral radical thyroidectomy (unilateral thyroidectomy and isthmus resection + ipsilateral central neck lymph node dissection). The control group was treated with conventional radical thyroidectomy, and the observation group was treated with indocyanine green guided radical thyroidectomy. The perioperative indicators, serum calcium and parathyroid hormone levels, and the incidence of complications were compared between the two groups. Result Before operation, there was no significant difference in serum calcium and parathyroid hormone levels between the two groups(P ＞ 0.05); One day after operation, the blood calcium and parathyroid hormone levels of the two groups were lower than those before operation, and the observation group was higher than that of the control group, with significant differences(P ＜ 0.001). The number of lymph node dissection in the observation group was more than that in the control group, and the intraoperative blood loss was less than that in the control group, with significant differences(P ＜ 0.001); There was no significant difference in operation time between the two groups(P ＞ 0.05). The incidences of recurrent laryngeal nerve injury and parathyroid gland MIS resection in the observation group were 0 and 4.35%(2/46), respectively, which were lower than those in the control group [13.04%(6/46) and 17.39%(8/46), respectively], and the differences were significant (P=0.026 and 0.045, respectively). Conclusion Radical thyroid cancer treatment under ICG guidance can increase the number of lymph node dissections, reduce the damage to normal tissues, and reduce the incidence of recurrent laryngeal nerve damage and parathyroid misresection.

Key words: Indocyanine green, Radical thyroid cancer surgery, Parathyroid hormone, Blood calcium, Complications