Abstract:

Objective To analyze the risk factors for postoperative metachronous liver metastasis in young patients with colorectal cancer. Method A retrospective analysis was conducted on the clinical data of 55 young postoperative cases of colorectal cancer with metachronous liver metastasis(occurrence group) and 55 young postoperative cases of colorectal cancer excluding metachronous liver metastasis(no occurrence group)from February 2011 to January 2018 in Jiangmen Central Hospital. Logistic regression analysis was used to identify independent risk factors aff ecting metachronous liver metastasis in young colorectal cancer patients. Result There were significant differences in concurrent liver metastasis, pathological grading, tissue type, depth of infiltration, lymph node metastasis, and family history between the group with and without the occurrence of the disease (P ＜ 0.05). Multivariate analysis showed that synchronous liver metastasis, pathological grading, depth of invasion, and lymph node metastasis were independent risk factors for postoperative metachronous liver metastasis in young colorectal cancer patients (OR=1.881, 1.142, 1.501, 2.734, P ＜ 0.05). Conclusion In clinical practice, the independent risk factors mentioned above can be comprehensively evaluated to reasonably assess the risk of metachronous liver metastasis in patients, in order to improve the survival rate of patients with metachronous liver metastasis.

Key words: Colorectal cancer, Metachronous liver metastasis, Young, Risk factors