Abstract:

Objective To investigate the effects of different pneumoperitoneum pressures on patients undergoing laparoscopic colorectal cancer surgery (LCS) and their impact on the quality of postoperative recovery period. Method 70 patients with LCS admitted to Gaozhou Traditional Chinese Medicine Hospital from October 2022 to October 2023 were selected and divided into a control group (controlled at 13 ～ 15mmHg) and an observation group (controlled at 8 ～ 12mmHg) based on diff erent levels of artifi cial pneumoperitoneum pressure, with 35 patients in each group. Result Compare the quality of recovery, cognitive function, stress response indicators, and gastrointestinal function recovery between two groups of patients. There was no significant diff erence in extubation time and anesthesia recovery time between the two groups of patients (P ＞ 0.05). The incidence of agitation during the awakening period in the observation group was lower than that in the control group, and the recovery of bowel sounds, anal exhaust, and postoperative fasting time were shorter than those in the control group, with signifi cant diff erences (P ＜ 0.05). The scores of the simple mental state examination scale for both groups of patients on postoperative day 1, 3, and 7 were lower than those on preoperative day 1, and the scores of the observation group were higher than those of the control group, with signifi cant diff erences (P ＜ 0.05). Compared with T0, the levels of cortisol and C-reactive protein in both groups increased from T1 to T3, and the levels of cortisol and C-reactive protein in the observation group were lower than those in the control group at the same time, with signifi cant diff erences (P ＜ 0.05). Conclusion Compared with high pneumoperitoneum pressure, adopting low pneumoperitoneum pressure in LCS treatment has less impact on patients' cognitive function, gastrointestinal function, and stress response, and can reduce the risk of agitation during the recovery period.

Key words: Pneumoperitoneum pressure, Laparoscope, Radical resection of colorectal cancer, Quality during the awakening period, Stress response