Abstract:

Micro ribonucleic acid (miRNA) refer to a highly conserved class of endogenous non-coding RNA, each composed of approximately 22 nucleotides. Numerous studies have demonstrated that miRNAs play a crucial role in the initiation and progression of hepatocellular carcinoma (HCC). MiRNAs function as regulatory molecules in the context of gene expression related to HCC. Some miRNAs also participate in the activation of cellular signaling pathways, and these pathways contribute to the occurrence and development of hepatocellular carcinoma. The review provides an overview of the research progress on the role of miRNAs in hepatocellular carcinoma, aiming to contribute insights into the identification of diagnostic markers for HCC and the exploration of moleculartargeted therapies.

Key words: Ribonucleic acid, Hepatocellular carcinoma, Targeted regulation, Biomarkers