临床普外科电子杂志 ›› 2024, Vol. 12 ›› Issue (2): 52-.

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腹腔镜结直肠癌根治术对结直肠癌患者术后肝肾功能的影响

  

  1. 柳州市融安县人民医院 普外科,广西 柳州 545400
  • 出版日期:2024-04-01 发布日期:2024-08-14

The impact of laparoscopic radical resection of colorectal cancer on liver and kidney function

  1. General Surgery Department of People’s Hospital of Rong’an County, Guangxi Liuzhou 545400, China
  • Online:2024-04-01 Published:2024-08-14

摘要:

目的 分析腹腔镜结直肠癌根治术对结直肠癌患者肝肾功能的影响。方法 选取 2021 年 3 月至 2023 年 3 月在柳州市融安县人民医院接受治疗的结直肠癌患者 120 例,根据随机数字表法分为对照组和试验组(各 60 例),对照组患者采用传统开腹手术,试验组患者行腹腔镜结直肠癌根治术治疗,比较两组患者的肝肾功能指标及术后并发症发生情况。结果 术前 1d,两组患者肝、肾功能指标无显著差异(P > 0.05)。术后 3d,试验组患者的乳酸脱氢酶水平较术前 1d 升高,差异有显著性(P < 0.05);且试验组患者的总蛋白、胆碱酯酶以及白蛋白水平显著低于对照组,尿酸水平显著低于对照组,差异均有显著性(P < 0.05)。试验组术后并发症发生率显著低于对照组(5.00% 比 16.67%;P=0.040)。结论 腹腔镜结直肠癌根治术会对患者的肝脏造成负担,对患者肾功能的影响较小,相较于传统开腹手术,并发症发生风险低。

关键词: 结直肠癌, 腹腔镜根治术, 肝肾功能, 影响

Abstract:

Objective To analyze the impact of laparoscopic radical resection of colorectal cancer on liver and kidney function in patients. Method 120 patients with colorectal cancer who received treatment at Rong’an County People’s Hospital in Liuzhou City from March 2021 to March 2023 were selected and randomly divided into a control group and an experimental group (each with 60 cases) using a random number table method. The control group received traditional open surgery, while the experimental group received laparoscopic radical resection for colorectal cancer. The liver and kidney function indicators and postoperative complications of the two groups of patients were compared. Result On the fi rst day before surgery, there was no signifi cant diff erence in liver and kidney function indicators between the two groups of patients (P > 0.05). Three days after surgery, the lactate dehydrogenase levels in the experimental group patients increased signifi cantly compared to the fi rst day before surgery (P < 0.05); The total protein, cholinesterase, and albumin levels of the experimental group patients were signifi cantly lower than those of the control group, and the uric acid level was signifi cantly lower than that of the control group, with signifi cant diff erences (P < 0.05). The incidence of postoperative complications in the experimental group was signifi cantly lower than that in the control group (5.00% vs. 16.67%; P=0.040). Conclusion Laparoscopic radical surgery for colorectal cancer can impose a burden on the liver function of patients and have a smaller impact on their renal function. Compared to traditional open surgery, the risk of complications is lower.

Key words: Colorectal cancer, Laparoscopic radical surgery, Liver and kidney function, Complications