关键词: 腹腔镜辅助, 胃癌根治术, 应激反应, 炎症反应

Abstract:

Objective To evaluate the application effect of laparoscopic assisted radical gastrectomy in patients undergoing gastric cancer surgery. Method Sixty hospitalized patients with gastric cancer admitted to Donghai County Traditional Chinese Medicine Hospital in Lianyungang City from September 2022 to August 2023 were selected and divided into a control group and an observation group based on different surgical methods. The control group received conventional gastric cancer radical surgery treatment, while the observation group received laparoscopic assisted gastric cancer radical surgery treatment. Compare the levels of adrenaline, cortisol, adrenocorticotropic hormone, as well as interleukin-6 and tumor necrosis factor-α between two groups of patients before and after surgery, compare the levels of high sensitivity C-reactive protein surgical situation, and the incidence of postoperative complications between the two groups of patients. Result Prior to surgery, levels of adrenaline, cortisol, adrenocorticotropic hormone, as well as interleukin-6 and tumor necrosis factor-α were measured in both groups of patients, the levels of high sensitivity C-reactive protein were all low and there was no significant difference (P ＞ 0.05). After surgery, the levels of adrenaline, cortisol, adrenocorticotropic hormone, as well as interleukin-6 and tumor necrosis factor-α in both groups of patients, the levels of high sensitivity C-reactive protein were all elevated, and the control group was significantly higher than the observation group.The surgical duration and first postoperative exhaust time of the observation group patients were shorter than those of the control group, and the intraoperative bleeding was less than that of the control group, with significant differences(P＜0.05). The total incidence of postoperative complications in the observation group was 3.33%, significantly lower than that in the control group (26.67%), with significant differences (P ＜ 0.05). Conclusion Laparoscopic assisted radical gastrectomy is less stressful for patients undergoing gastric cancer surgery and has a lower incidence of postoperative complications.

Key words: Laparoscopic assistance, Radical gastrectomy for gastric cancer, Stress response, inflammatory reaction