临床普外科电子杂志 ›› 2023, Vol. 11 ›› Issue (4): 11-.

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胰十二指肠切除术后胃排空障碍的研究进展

  

  1. 1. 北京协和医学院 研究生院,北京 100730;2. 北京医院 中国医学科学院老年医学研究院 国家老年医学中心 普通外科,北京 100730
  • 出版日期:2023-10-01 发布日期:2023-12-20

Research progress on the delayed gastric emptying after pancreaticoduodenectomy

  1. 1. Graduate School of Peking Union Medical College, Beijing 100730, China; 2. Department of General Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Online:2023-10-01 Published:2023-12-20

摘要:

胰十二指肠切除术(pancreaticoduodenectomy,PD)目前已成为治疗壶腹周围区恶性肿瘤、胰腺良性病变以及胰腺损伤的标准手术方式。由于手术涉及的消化器官较多,操作复杂,术后出现的并发症较多,其中胃排空障碍是PD 术后最常见的并发症之一。目前,胃排空障碍的病因及发病机制尚未完全阐明,有研究认为PD 术后胃排空障碍可能与患者术前个体情况以及手术方式如保留或不保留幽门PD、胃空肠吻合术式等相关。针对胃排空障碍的治疗仍以非手术治疗为主,其中大多数患者在得到诸如营养支持治疗、胃肠减压、药物、针灸、胃电刺激等保守治疗后获得痊愈。本文主要探讨PD 术后胃排空障碍发生的相关因素,为预防及治疗胃排空障碍提供理论依据。

关键词: 胰十二指肠切除术, 胃排空障碍, 研究进展

Abstract:

Pancreaticoduodenectomy (PD) has become the standard treatment for malignant tumors of the periampullary malignancies, and some benign pancreatic diseases and pancreatic injuries. Due to the large number of digestive organs involved in the surgery and the complexity of the operation, there are many postoperative complications, among which gastric emptying disorder is one of the most common complications after PD surgery. At present, the etiology and pathogenesis of gastric emptying disorders have not been fully elucidated. Some studies suggest that gastric emptying disorders after PD surgery may be related to the individual condition of the patient before surgery and surgical methods such as retaining or not retaining pyloric PD and gastrojejunostomy.

Non surgical treatment is still the main treatment for gastric emptying disorders. Most of the patients recovered after receiving conservative treatment such as nutritional support treatment, gastrointestinal decompression, gastroprokinetic agent, acupuncture and moxibustion, gastric electrical stimulation, etc. This article mainly discusses the related factors of gastric emptying disorder after pancreatoduodenectomy and provide theoretical basis for prevention and treatment of gastric emptying disorder.

Key words: Pancreaticoduodenectomy, Gastric emptying disorders, Research progress