甲状腺乳头状癌不同超声征象在预测淋巴结转移价值中的临床研究

临床普外科电子杂志 ›› 2023, Vol. 11 ›› Issue (1): 8-.

甲状腺乳头状癌不同超声征象在预测淋巴结转移价值中的临床研究

1. 牡丹江市肿瘤医院超声科，黑龙江省牡丹江市 157000；2. 中日友好医院介入医学科，北京 100029

出版日期:2023-01-01 发布日期:2023-03-07

Clinical study on different ultrasonic signs in predicting lymph node metastasis of thyroid papillary carcinoma

1. Ultrasound Department of Mudanjiang Tumor Hospital, Heilongjiang Mudanjiang 157000, China; 2. Interventional Medicine Department of China-Japan Friendship Hospital, Beijing 100029, China

Online:2023-01-01 Published:2023-03-07

摘要/Abstract

摘要：

目的研究伴淋巴结转移的甲状腺乳头状癌（papillary thyroid carcinoma,PTC）病灶超声影像学特征。方法回顾性分析2015 年8 月至2020 年12 月在中日友好医院行热消融治疗的PTC 患者的临床资料，根据转移情况分为有淋巴结转移组（转移组）和无淋巴结转移组（无转移组）。比较两组的甲状腺常规超声（ultrasound，US）及超声造影（contrast-enhancedultrasound，CEUS）不同特征的差异。结果共纳入91 例PTC 患者，其中转移组31 例，无转移组60 例。常规超声转移组PTC 结节纵横比≥ 1 和结节内有微钙化的比例高于无转移组，差异有显著性（P ＜ 0.05）；超声造影转移组PI 差小于无转移组，差异有显著性（P ＜ 0.05）。受试者操作特征曲线分析显示：曲线下面积为0.63，最佳临界值PI 差为-7.3，该点预测敏感度为42%，特异度为43%。结论甲状腺乳头状癌转移组与无转移组有不同的影像学特点，明确上述征象有助于预测PTC 生物学特征。

关键词: 甲状腺乳头状癌, 热消融, 超声造影, 淋巴结转移

Abstract:

Objective To study the ultrasonographic features of papillary thyroid carcinoma nodules (PTC) with lymph node metastasis (LNM). Method The data of patients with PTC who underwent thermal ablation from July 2019 to December 2020 were retrospectively studied. The patients were divided into LNM group and non-LNM group. The imaging features and parameters between the two groups both on conventional ultrasound and contrast-enhanced ultrasound were compared. Result A total of 91 patients with PTC were included, including 31 cases in the LNM group and 60 cases in the non-LNM group. In the LNM group, the proportion of nodules with length/width ratio larger than 1.0 or with microcalcification were higher than those in the non-LNM group, and the difference were statistically significant (P ＜ 0.05); The peak intensity (PI)difference was lower than that in the non-LNM group (P ＜ 0.05). ROC curve analysis was performed to test the diagnostic efficiency of PI difference to diagnose PTC with LNM. The area under the curve was 0.63, the optimum critical value was -7.3, the sensitivity was 42% and the specificity was 43%. Conclusion The imaging features and parameter showed significant differences between the LNM group and non-LNM group. The above results may be helpful to predict the biological characteristics of PTC.

Key words: Papillary thyroid carcinoma, Thermal ablation, Contrast-enhanced ultrasound, Lymph node metastasis

刘彩虹, 郝莹, 赵朕龙, 魏莹, 彭丽丽, 李妍, 于明安. 甲状腺乳头状癌不同超声征象在预测淋巴结转移价值中的临床研究 [J]. 临床普外科电子杂志, 2023, 11(1): 8-.

LIU Caihong, HAO Ying, ZHAO Zhenlong, WEI Ying, PENG Lili, LI Yan, YU Ming’an. Clinical study on different ultrasonic signs in predicting lymph node metastasis of thyroid papillary carcinoma [J]. Journal of General Surgery for Clinicians, 2023, 11(1): 8-.