临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (3): 95-.

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腹腔镜根治术与传统开腹手术治疗结直肠癌的临床分析

  

  1. 1. 广州市增城区中心医院 普通外科,广东 广州 511300;2. 南方医科大学南方医院 普通外科,广东 广州 510515
  • 出版日期:2022-07-01 发布日期:2022-10-24

Clinical analysis of laparoscopic radical resection and traditional open surgery in the treatment of colorectal cancer

  1. 1. General Surgery Department of Guangzhou Zengcheng District Central Hospital, Guangdong Guangzhou 511300, China; 2. General Surgery Department of Nanfang Hospital of Southern Medical University, Guangdong Guangzhou 510515, China
  • Online:2022-07-01 Published:2022-10-24

摘要:

目的 分析结直肠癌患者经腹腔镜根治术与传统开腹手术治疗的价值。方法 筛选2019 年3 月至2022 年2 月广州市增城区中心医院收治的结直肠癌患者80 例作为研究对象,采用随机抽样法分为两组各40 例,对照组给予传统开腹手术治疗,观察组给予腹腔镜根治术,对比两组患者近期疗效、免疫应激指标、并发症发生情况。结果 观察组患者术中出血量少于对照组,排气时间、住院时间、进食时间低于对照组,差异均有显著性(P < 0.05);观察组患者CD3+、CD4+、CD8+T 细胞高于对照组,且并发症发生率低于对

照组,差异均有显著性(P < 0.05)。结论 腹腔镜根治术治疗结直肠癌可缩短排气、进食及住院时间,同时可提高机体免疫功能,避免术后出现各类并发症影响预后效果。

关键词: 腹腔镜根治术, 传统开腹手术, 结直肠癌, 近期疗效, 免疫应激指标

Abstract:

Objective To analyze the value of laparoscopic radical resection and traditional laparotomy in the treatment of colorectal cancer. Method 80 patients with colorectal cancer admitted to the Guangzhou Zengcheng District Central Hospital from March 2019 to February 2022 were selected as the research objects. They were randomly divided into two groups with 40 patients in each group. The control group was treated with traditional open surgery, and the observation group was treated with laparoscopic radical surgery. The short-term efficacy, immune stress indicators and complications of the two groups were compared. Result The amount of bleeding in the observation group was less than that in the control group, and the exhaust time, hospitalization time and eating time were significantly lower than those in the control group (P < 0.05); The levels of CD3+, CD4+, CD8+ T cell in the observation group were higher than those in the control group, and the complication rate was lower than that in the control group (P < 0.05). Conclusion Laparoscopic radical resection for colorectal cancer can shorten the time of exhaust, eating and hospitalization, improve the immune function, and avoid all kinds of postoperative complications affecting the prognosis.

Key words: Laparoscopic radical operation, Traditional open surgery, Colorectal cancer, Short term efficacy, Immune stress index