临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (3): 91-.

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腹腔镜下右半结肠癌根治术对结肠癌患者胃肠功能的影响

  

  1. 苏州市立医院 胃肠外科,江苏 苏州 215000
  • 出版日期:2022-07-01 发布日期:2022-10-24

Effect of laparoscopic radical right colon cancer surgery on gastrointestinal function in patients with colon cancer

  1. Gastrointestinal Surgery Department of Suzhou Municipal Hospital, Jiangsu Suzhou 215000, China
  • Online:2022-07-01 Published:2022-10-24

摘要:

目的 探讨采用腹腔镜下右半结肠癌根治术治疗结肠癌患者对其胃肠功能恢复的影响。方法 抽选2020 年1 月至2021 年12 月苏州市立医院收治的结肠癌患者66 例,根据蓝绿小球抽签结果分为观察组和对照组各33 例。对照组患者采取开腹右半结肠癌根治术治疗,观察组患者实施腹腔镜右半结肠癌根治术治疗,记录比较两组患者术后恢复情况,对比两组患者手术前后胃肠功能指标及免疫功能指标变化,以及术后并发症发生情况。结果 观察组患者术后肠鸣音恢复、排气、排便及住院时间均明显短于对照组(P< 0.05)。两组患者术前胃肠功能指标、免疫功能指标比较,差异无显著性(P > 0.05);术后观察组患者胃动素、胃泌素水平均高于对照组,且CD4+T 细胞高于对照组,CD8+T 细胞低于对照组(P < 0.05)。另外,观察组患者术后并发症总发生率低于对照组(P <0.05)。结论 采取腹腔镜右半结肠癌根治术治疗结肠癌患者,能够有效促进患者术后恢复,对患者胃肠功能的影响小,并发症少,安全性理想。

关键词: 腹腔镜右半结肠癌根治术, 结肠癌, 胃肠功能, 免疫功能

Abstract:

Objective To investigate the effect of laparoscopic radical resection of right colon cancer on the recovery of gastrointestinal function in patients with colon cancer. Method 66 patients with colon cancer admitted to Suzhou Municipal Hospital from January 2020 to December 2021 were selected and divided into observation group and control group with 33 cases in each group according to the results of blue-green ball lottery. The patients in the control group were treated with open radical resection of right colon cancer, and the patients in the observation group were treated with laparoscopic radical resection of right colon cancer. The postoperative recovery of the two groups were recorded and compared, and the changes of gastrointestinal function and immune function indexes before and after operation and the occurrence of postoperative complications were compared between the two groups. Result The recovery of bowel sounds, exhaust, defecation and hospital stay in the observation group were significantly shorter than those in the control group (P < 0.05). There was no significant difference in preoperative gastrointestinal function and immune function between the two groups (P > 0.05); the levels of

motilin and gastrin in the observation group were higher than those in the control group, CD4+ T cell was higher than that in the control group, and CD8+ T cell was lower than that in the control group (P < 0.05). In addition, the total incidence of postoperative complications in the observation group was lower than that in the control group (P< 0.05). Conclusion Laparoscopic radical resection of right colon cancer can effectively promote the postoperative recovery of patients with colon cancer, with little impact on gastrointestinal function, less complications and ideal safety.

Key words: Laparoscopic radical resection of right colon cancer, Colon cancer, Gastrointestinal function, Immunologic function