关键词: 双极电凝镊, 甲状旁腺激素, 快速检测, 甲状旁腺, 保护

Abstract:

Objective To study the protective effect of bipolar electrocoagulation tweezers combined with rapid detection of parathyroid hormone (PTH) on parathyroid gland during operation. Method 205 patients with thyroid tumors treated by open thyroid surgery in Macheng People's Hospital from February 2020 to August 2021 were randomly divided into control group (n=102) and intervention group (n=103). The patients in the control group were treated with routine operation. The surgeon in charge of the operation used ultrasonic scalpel and judged the parathyroid gland by experience and naked eyes. The intervention group used bipolar electrocoagulation forceps and performed rapid PTH detection. The operation time, intraoperative bleeding volume, postoperative drainage volume, total hospital stay, PTH value, serum calcium value, incidence of hypoparathyroidism and quality of life were compared between the two groups. Result The operation time and postoperative drainage volume in the control group were (201.84±16.37) min and (80.46±7.69) ml respectively, while those in the intervention group were  (153.09±11.82) min and (51.37±4.75) ml respectively, with significant difference (P ＜ 0.05); there was no significant difference in the amount of intraoperative bleeding and total length of stay between the two groups (P ＞ 0.05). On the 3rd day after operation, the PTH value and serum calcium value in the control group were (5.83±0.54) pg/ml and (1.90±0.15) mmol/l respectively, and those in the intervention group were (11.06±0.97)pg/ml and (2.07±0.16) mmol/l respectively, which were significantly higher than those in the control group (P＜ 0.05); there was no significant difference in PTH and serum calcium between the two groups one month after operation (P ＞ 0.05). The incidences of temporary hypoparathyroidism and permanent hypoparathyroidism in the control group were 77.45% (79/102) and 4.90% (4/102), while those in the intervention group were 51.46%(56/103) and 0 respectively, which were significantly lower than those in the control group (P ＜ 0.05). The score of thyroid cancer specific quality of life scale in the control group was (19.70±1.52) and that in the intervention group was (22.07±1.83), which was significantly higher than that in the control group (P ＜ 0.05). Conclusion Bipolar

electrocoagulation forceps and PTH rapid detection technology in open thyroid surgery can shorten the operation time, reduce the body damage, better protect the parathyroid gland, and improve the quality of life.

Key words: Bipolar electrocoagulation tweezers, Parathyroid hormone, Rapid detection, Parathyroid gland, Protect