关键词: 序贯应用, 肠内营养, 肠外营养, 重症监护室, 老年肿瘤, 营养状况, 预后

Abstract:

Objective To analyze the effect of sequential enteral and parenteral nutrition on nutrition and prognosis of elderly cancer patients in intensive care unit. Method 92 elderly cancer patients admitted to the intensive care unit of Yunnan Cancer Hospital from March 2020 to May 2021 were randomly divided into two groups with 46 cases in each group by different nutritional treatment methods. The control group was given parenteral nutrition support, and the observation group was given enteral and parenteral nutrition support in sequence. The changes of nutritional indexes, immune indexes, hospitalization and complications before and after intervention were compared between the two groups. Result There was no significant difference in the levels of serum protein, prealbumin and hemoglobin between the two groups before intervention (P ＞ 0.05). After intervention, the levels of serum protein, prealbumin and hemoglobin in the observation group were higher than those in the control group (P ＜ 0.05). There was no significant difference in the levels of IgG and IgM between the two groups before intervention (P ＞ 0.05). After intervention, the levels of IgG and IgM in the observation group were higher than those in the control group (P ＜ 0.05). The ventilator time and hospital stay in the observation group were shorter than those in the control group (P ＜ 0.05), and the incidence of complications was 13.0%, lower than 37.0% in the control group (P ＜ 0.05). Conclusion Sequential enteral and parenteral nutrition can improve the nutritional status of elderly cancer patients in intensive care unit, improve their immune ability, shorten the length of hospital stay, reduce the incidence of complications and promote rehabilitation. It is of great significance to improve their prognosis.

Key words: Sequential application, Enteral nutrition, Parenteral nutrition, Intensive care unit, Senile tumor, Nutritional status, Prognosis