临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (2): 24-.

• • 上一篇    下一篇

腹腔镜与传统开腹手术对结直肠癌的临床疗效及并发症发生率评价

  

  1. 徐州市沛县人民医院 普外科,江苏 徐州 221600
  • 出版日期:2022-04-01 发布日期:2022-07-18

Clinical evaluation of laparoscopic and traditional open surgery in the treatment of colorectal cancer

  1. Surgery Department of Peixian People's Hospital of Xuzhou City, Jiangsu Xuzhou 221600, China
  • Online:2022-04-01 Published:2022-07-18

摘要:

目的 对比传统开腹手术与腹腔镜手术治疗结直肠癌患者的临床疗效及对术后并发症的影响。方法 选取2018 年1 月至2021 年9 月徐州市沛县人民医院收治的60 例结直肠癌患者作为研究对象,根据手术方式不同分为传统开腹手术组(对照组)与腹腔镜手术组(观察组),各30 例。对比两组临床治疗效果,以及术前、术后3d 患者氧化应激水平及术后并发症发生情况。结果 观察组患者术中出血量(70.35±23.32)ml,少于对照组患者术中出血量(164.83±43.24)ml,手术时间(146.48±15.34)min、肠道功能恢复时

间(60.35±13.43)h、住院时间(11.83±5.32)d 均短于对照组(P < 0.05);治疗前,两组患者的超氧化物歧化酶(superoxide dismutase,SOD)、血清丙二醛(malondialdehyde,MDA)水平无显著差异(P > 0.05);治疗后,观察组患者的SOD、MDA 水平分别为(85.30±12.99)kU/L、(6.01±1.83)mmol/L,对照组患者的SOD、MDA 水平分别为(74.81±11.23)kU/L、(7.29±1.92)mmol/L,差异均有显著性(P < 0.05);观察组患者并发症总发生率低于对照组(P < 0.05)。结论 腹腔镜手术治疗结直肠癌患者的效果优于开腹手术治疗,患者创伤小,恢复快,且安全性高。

关键词: 结直肠癌, 腹腔镜, 开腹手术, 疗效

Abstract:

Objective To compare the clinical efficacy and postoperative complications of traditional laparotomy and laparoscopic surgery in patients with colorectal cancer. Method A total of 60 patients with colorectal cancer admitted to our hospital from January 2018 to September 2021 were selected as the research subjects, and were divided into traditional open surgery group (control group) and laparoscopic surgery group (observation group) by different surgical methods, with 30 patients in each group. The clinical treatment effects of the two groups were compared, and the oxidative stress level and postoperative complications were compared before and 3 days after surgery. Result The amount of intraoperative bleeding in the observation group was (70.35±23.32)ml, which was less than that in the control group (164.83±43.24)ml. The operation time was (146.48±15.34)

min, the recovery time of intestinal function was (60.35±13.43)h and the hospital stay was (11.83±5.32)d, which were shorter than those in the control group (P < 0.05). Before treatment, there was no significant difference in the levels of superoxide dismutase(SOD) and serum malondialdehyde(MDA) between the two groups (P > 0.05); after treatment, the levels of SOD and MDA in the observation group were (85.30±12.99)kU/L and (6.01±1.83)mmol/L respectively, and those in the control group were (74.81±11.23)kU/L and (7.29±1.92)mmol/L respectively (P < 0.05). The total incidence of complications in the observation group was lower than that in the control group (P < 0.05). Conclusion Laparoscopic surgery is better than open surgery in the treatment of colorectal cancer, the patients have less trauma, rapid recovery and high safety.

Key words: Colorectal cancer, Laparoscope, Open operation, Curative effect