临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (1): 56-.

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不同甲状腺癌切除术治疗甲状腺癌患者的临床疗效分析

  

  1. 宣城市仁杰医院 普通外科,安徽 宣城 242000
  • 出版日期:2022-01-01 发布日期:2022-03-22

Clinical efficacy analysis of different thyroid cancer resection in patients with thyroid cancer 

  1. General Surgery Department of Xuancheng Renjie Hospital,Anhui Xuancheng 242000,China
  • Online:2022-01-01 Published:2022-03-22

摘要:

目的 探讨甲状腺癌切除术对甲状腺癌患者炎症指标分析。方法 将2019 年1 月至2021 年9 月在宣城市仁杰医院治疗的30 例甲状腺癌患者根据手术方式分为两组,对照组使用甲状腺患侧叶切除+ 对侧次全切除术,观察组使用甲状腺患侧叶切除术。对比两组患者各项手术指标、并发症发生率、甲状腺激素指标、甲状旁腺激素(parathyroid hormone,PTH)及血钙水平。结果 观察组患者手术时间、术中出血量、术后镇痛时间、住院时间均短于对照组(P < 0.05);观察组患者切口感染、低钙血症、甲状腺功能低下、喉返神经损伤等并发症发生率明显低于对照组(P < 0.05);观察组患者术后3d 的总三碘甲腺原氨酸(total triiodothyronine,TT3)、总甲状腺素(total thyroxine,TT4)以及PTH、血钙明显高于对照组(P < 0.05),游离三碘甲腺原氨酸(free  triiodothyronine,FT3)、游离甲状腺素(free thyroxine,FT4)明显低于对照组(P < 0.05)。结论 甲状腺患侧叶切除术对甲状腺癌的创伤小,术后并发症发生率低,能部分保留甲状腺生理功能,维持甲状腺激素水平,避免PTH、血钙水平持续降低,具有积极的临床意义。

关键词: 甲状腺癌, 甲状腺患侧叶切除术, 对侧次全切除术, 甲状腺激素, 疗效

Abstract:

Objective To investigate the inflammatory index analysis of thyroid cancer resection in thyroid cancer patients. Method Thirty patients of thyroid cancer treated at Xuancheng Renjie Hospital from January 2019 to September 2021 were randomly divided into two groups, the control group used the thyroid lobectomy plus contralateral subtotal resection, and the observation group

used the thyroid lobectomy, compared the two groups with the operating indexes, complication rate, thyroid hormone index, parathyroid hormone (PTH) and blood calcium levels. Result The operation time, intraoperative bleeding amount, postoperative analgesia time and hospital stay in the observation group were shorter than those in the control group (P < 0.05);The incidence of incision infection, hypocalcemia, hypothyroid function, and recurrent laryngeal nerve injury was significantly lower than that in the control group (P < 0.05); Total triiodothyronine(TT3), total thyroxine (TT4), PTH and blood calcium were significantly higher than the control group (P < 0.05), and free triiodothyronine (FT3), free thyroxine (FT4) were significantly lower than the control group (P < 0.05). Conclusion Thyroid lobectomy has small trauma to thyroid cancer and low incidence of postoperative complications, which can partially retain the physiological function of the thyroid, maintain thyroid hormone levels, and avoid the continuous reduction of PTH and blood calcium levels, which has positive clinical significance.

Key words: Thyroid cancer, Thyroid lobectomy, Contralateral subtotal resection, Thyroid hormone, Efficacy