瑞芬太尼复合丙泊酚于腹腔镜胆囊切除术中的麻醉效果研究

临床普外科电子杂志 ›› 2022, Vol. 10 ›› Issue (1): 45-.

瑞芬太尼复合丙泊酚于腹腔镜胆囊切除术中的麻醉效果研究

江苏省人民医院溧阳分院麻醉科，江苏溧阳 213300

出版日期:2022-01-01 发布日期:2022-03-22

Anesthetic effect of remifentanil combined with propofol in laparoscopic cholecystectomy

Anesthesiology Department of Liyang Branch of Jiangsu Provincial People's Hospital,Jiangsu Liyang 213300,China

Online:2022-01-01 Published:2022-03-22

摘要/Abstract

摘要：

目的探讨应用瑞芬太尼复合丙泊酚于腹腔镜胆囊切除术中的麻醉效果。方法选取2020 年7 月至2021 年7 月在江苏省人民医院溧阳分院接受腹腔镜胆囊切除术治疗的88 例患者，根据麻醉方法分为对照组（44 例，应用丙泊酚麻醉）、观察组（44 例，应用瑞芬太尼复合丙泊酚麻醉），比较两组患者麻醉恢复效果，不良反应发生状况，手术前后收缩压、舒张压、心率水平及简易精神状态检查量表(Mini-Mental State Examination,MMSE) 评分。结果相较于对照组，观察组患者定向力恢复、意识恢复、拔管、自主呼吸恢复等时间更短，视觉模拟评分法评分更低（P＜ 0.05）。术后，与对照组比较，观察组患者收缩压、舒张压、心率水平更优（P ＜0.05）。拔管后1h、24h，相比对照组，观察组MMSE 评分更高（P ＜ 0.05）。与对照组不良反应发生率（13.64%）比较，观察组患者的并发症发生率（2.27%）更低（P ＜ 0.05）。结论应用腹腔镜胆囊切除术时，采用瑞芬太尼复合丙泊酚麻醉效果理想，可缩短患者恢复时间，对血流动力学影响较小，有利于患者认知功能恢复，减少不良反应的发生。

关键词: 瑞芬太尼, 丙泊酚, 腹腔镜胆囊切术, 麻醉效果

Abstract:

Objective To investigate the anesthetic effect of remifentanil combined with propofol in laparoscopic cholecystectomy. Method 88 patients who underwent laparoscopic cholecystectomy in Liyang branch of Jiangsu Provincial People's Hospital from July 2020 to July 2021 were selected, they were randomly divided into control group (44 cases, anesthesia with propofol) and observation group (44 cases, anesthesia with remifentanil combined with propofol). The anesthesia recovery effect, adverse

reactions, systolic blood pressure, diastolic blood pressure, heart rate level before and after operation and the score of Mini Mental State Examination (MMSE) were compared between the two groups. Result Compared with the control group, the recovery of orientation, consciousness, extubation and spontaneous breathing in the observation group were shorter, The visual analogue score was lower (P ＜ 0.05). After operation, the levels of systolic blood pressure, diastolic blood pressure and heart rate in the observation group were better than those in the control group (P ＜ 0.05). At 1h and 24h after extubating, the MMSE score in the observation group was higher than that in the control group (P ＜ 0.05). Compared with the incidence of adverse reactions in the control group (13.64%), the incidence of complications in the observation group (2.27%) was lower. Conclusion Remifentanil combined with propofol anesthesia is effective in laparoscopic cholecystectomy, which can shorten the recovery time of patients, has little impact on hemodynamics, is conducive to the recovery of cognitive function and reduce the occurrence of adverse reactions.

Key words: Remifentanil, Propofol, Laparoscopic cholecystectomy, Anesthetic effect

孙睿. 瑞芬太尼复合丙泊酚于腹腔镜胆囊切除术中的麻醉效果研究 [J]. 临床普外科电子杂志, 2022, 10(1): 45-.

SUN Rui. Anesthetic effect of remifentanil combined with propofol in laparoscopic cholecystectomy [J]. Journal of General Surgery for Clinicians, 2022, 10(1): 45-.