临床普外科电子杂志 ›› 2021, Vol. 9 ›› Issue (4): 26-.

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内镜联合药物诊治肝硬化食管-胃底静脉曲张破裂出血的疗效及再出血影响因素

  

  1. 深圳市中西医结合医院 脾胃病科,广东 深圳 518104
  • 出版日期:2021-10-01 发布日期:2021-12-23

The curative effect of endoscope combined with drugs in diagnosis and treatment of esophageal and gastric variceal bleeding in liver cirrhosis and the influencing factors of rebleeding

  1. Spleen and Stomach Department of Shenzhen Integrated Traditional Chinese and Western Medicine Hospital, Shenzhen 518104, Guangdong
  • Online:2021-10-01 Published:2021-12-23

摘要:

目的 探讨内镜联合药物诊治肝硬化食管-胃底静脉曲张破裂出血的疗效及再出血影响因素。方法 选取2019年2月至2021年2月深圳市中西医结合医院收治的肝硬化食管-胃底静脉曲张破裂出血患者80例,患者均接受内镜下食管静脉曲张套扎术联合内镜下静脉曲张硬化注射术治疗,根据术后是否再出血,分为复发组(n=22)与未复发组(n=58),分析影响内镜联合药物治疗肝硬化食管-胃底静脉曲张破裂出血的疗效及再出血的危险因素。结果 全部患者术后均成功止血,止血成功率为100.00%;复发组与未复发组的性别、年龄、门静脉内径、Child-Pugh评分、白蛋白浓度与血钠水平差异无显著性(P>0.05);门静脉内径、Child-Pugh评分为内镜联合药物治疗肝硬化食管-胃底静脉曲张破裂出血后再出血的危险因素(P<0.05)。结论 内镜联合药物诊治肝硬化食管-胃底静脉曲张破裂出血的疗效确切,内镜联合药物治疗肝硬化食管-胃底静脉曲张破裂出血后再出血的危险因素包括门静脉内径与Child-Pugh评分。

关键词: 肝硬化, 食管-胃底静脉曲张, 出血, 内镜, 因素

Abstract:

Objective To investigate the efficacy of endoscope combined with drugs in the diagnosis

and treatment of esophageal and gastric variceal bleeding in liver cirrhosis and the influencing factors

of rebleeding. Methods From February 2019 to February 2021, 80 patients with esophageal and gastric

varices rupture and bleeding of liver cirrhosis treated in Shenzhen Integrated Traditional Chinese

and Western Medicine Hospital were selected. All patients were treated with endoscopic esophageal

varices ligation combined with endoscopic varices sclerotherapy injection. They were divided into

recurrent group (n=22) and non-recurrent group (n=58) according to whether there was rebleeding after

operation, to analyze the efficacy of endoscopy combined with drugs in the treatment of esophageal and

gastric variceal bleeding in liver cirrhosis and the risk factors of rebleeding. Results All patients were

successfully hemostatic, and the success rate of hemostasis was 100.00%; There was no significant

difference in gender, age, portal vein diameter, Child-Pugh score, albumin concentration and blood

sodium level between recurrent group and non-recurrent group (P>0.05); Portal vein diameter and Child-Pugh score were the risk factors of rebleeding after endoscopic combined with drug treatment of

esophageal and gastric varices bleeding in liver cirrhosis (P<0.05). Conclusion Endoscope combined

with drugs is effective in the diagnosis and treatment of esophageal and gastric variceal bleeding in liver

cirrhosis. The risk factors of rebleeding after esophageal and gastric variceal bleeding in liver cirrhosis

include portal vein diameter and Child-Pugh score.

Key words: Liver cirrhosis, Esophageal and gastric varices, Bleeding, Endoscope, Factor