内镜逆行阑尾炎治疗术对急性阑尾炎伴周围脓肿形成炎症因子、疗效及术后并发症的影响

临床普外科电子杂志 ›› 2021, Vol. 9 ›› Issue (4): 15-.

内镜逆行阑尾炎治疗术对急性阑尾炎伴周围脓肿形成炎症因子、疗效及术后并发症的影响

达州市中西医结合医院消化内科，四川达州 635000

出版日期:2021-10-01 发布日期:2021-12-23
基金资助:
达州市卫健委（2019026）

Effect of endoscopic retrograde appendicitis therapy treatment on inflammation factor of acute appendicitis with peripheral abscess, efficacy and postoperative complications

Gastroenterology Department of Dazhou Hospital of Integrated Traditional Chinese and Western Medicine, Dazhou 635000, Sichuan

Online:2021-10-01 Published:2021-12-23

摘要/Abstract

摘要：

目的探讨内镜逆行急性阑尾炎伴周围脓肿形成治疗的临床疗效及安全性，为临床治疗提供参考依据。方法选取2018 年6 月至2020 年6 月达州市中西医结合医院收治的86 例急性阑尾炎伴周围脓肿形成患者，根据随机数字表达法分为研究组和对照组，各43 例。研究组患者给予内镜逆行阑尾炎治疗术(endoscopic retrograde appendicitis therapy,ERAT)，对照组给予腹腔镜阑尾切除术(laparoscopic appendectomy,LA) 治疗。比较两组患者治疗1 周总有效率、术后2 周并发症发生率，术前、术后1 周炎症因子指标(C 反应蛋白、白介素-6、白介素-8) 水平。结果治疗1 周，研究组总有效率为95.35%（41/43），高于对照组83.72%(36/43)，差异具有显著性（P ＜ 0.05）。治疗前，两组患者C 反应蛋白、白介素-6、白介素-8 比较差异无显著性（P ＞ 0.05）；治疗1 周，研究组患者C 反应蛋白、白介素-6、白介素-8 低于对照组，差异具有显著性（P ＜ 0.05）。术后2 周，研究组患者术后并发症发生率为4.65%(2/43)，低于对照组13.95%(6/43)，差异具有显著性（P＜ 0.05）。结论采取内镜逆行手术治疗急性阑尾炎伴周围脓肿形成，可降低炎症因子水平，减少术后并发症，改善疗效。

关键词: 内镜, 急性阑尾炎, 阑尾周围脓肿形成

Abstract:

Objective To investigate the clinical efficacy and safety of endoscopic retrograde acute

appendicitis with peripheral abscess formation, and to provide reference basis for clinical treatment.

Methods 86 patients with acute appendicitis with peripheral abscess treated in Dazhou integrated

traditional Chinese and Western medicine hospital from June 2018 to June 2020 were randomly divided

into study group and control group, with 43 cases in each group. The study group was treated with

endoscopic retrograde appendicitis therapy (ERAT), and the control group was treated with laparoscopic

appendectomy (LA). The total effective rate, the incidence of complications 2 weeks after operation and the levels of inflammatory factors (C-reactive protein, interleukin-6 and interleukin-8) before and

1 week after operation were compared between the two groups. Results After one week of treatment,

the total effective rate in the study group was 95.35% (41/43), which was significantly higher than

83.72% (36/41) in the control group (P ＜ 0.05). Before treatment, there was no significant difference in

C-reactive protein, interleukin-6 and interleukin-8 between the two groups (P ＞ 0.05); After one week of

treatment, C-reactive protein, interleukin-6 and interleukin-8 in the study group were significantly lower

than those in the control group (P ＜ 0.05). Two weeks after operation, the incidence of postoperative

complications in the study group was 4.65% (2/43), lower than 13.95% (6/43) in the control group (P

＜ 0.05). Conclusion Endoscopic retrograde surgery for patients with acute appendicitis with peripheral

abscess can reduce the level of inflammatory factors, reduce postoperative complications and improve the

curative effect.

Key words: Endoscopy, Acute appendicitis, Periappendiceal abscess formation

李权春, 彭雷, 张春雷, 严欢. 内镜逆行阑尾炎治疗术对急性阑尾炎伴周围脓肿形成炎症因子、疗效及术后并发症的影响 [J]. 临床普外科电子杂志, 2021, 9(4): 15-.

LI Quanchun, PENG Lei, ZHANG Chunlei, YAN Huan. Effect of endoscopic retrograde appendicitis therapy treatment on inflammation factor of acute appendicitis with peripheral abscess, efficacy and postoperative complications [J]. Journal of General Surgery for Clinicians, 2021, 9(4): 15-.

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