临床普外科电子杂志 ›› 2021, Vol. 9 ›› Issue (3): 57-.

• • 上一篇    

.O.I.S.T理论在3、4期压力性损伤临床实践中的应用研究

  

  1. 广州医科大学附属第四医院 普外科,广东 广州 511300
  • 出版日期:2021-07-01 发布日期:2021-09-24
  • 基金资助:

    广东省医学科学技术研究基金(A2019018)

Application of M.O. I. S. T. theory in the clinical practice of stage 3 and stage 4 stress injury

  1. General Surgery Department of The Fourth Affiliated Hospital of Guangzhou Medical University, Guangzhou 511300, Guangdong
  • Online:2021-07-01 Published:2021-09-24

摘要:

摘要:目的 探讨M.O.I.S.T理论在3、4期压力性损伤临床实践中的应用研究。方法 以2019年7月至2020年10月在广州医科大学附属第四医院住院的3、4期压力性损伤患者64例为研究对象,随机分为观察组和对照组,每组32例。对照组采用封闭负压引流(vacuum-assisted closure,VAC),观察组采用VAC联合持续微氧疗法。结果 干预后,观察组伤口缩小率高于对照组(P<0.05);观察组肉芽组织覆盖率、伤口愈合率高于对照组,伤口疼痛评分、伤口细菌培养率低于对照组,差异有显著性(P<0.05)。两组患者伤口pH值、CD34+T细胞、增殖细胞核抗原(proliferating cell nuclear antigen,PCNA)比较,差异有显著性(P<0.05)。结论 VAC联合微氧疗法可以加速3、4期压力性损伤患者伤口面积缩小,促进肉芽组织生长及创面愈合,减轻伤口疼痛感,减少伤口细菌残留,改善伤口酸碱度及组织免疫学情况。

关键词: 封闭负压引流, 持续微氧疗法, 压力性损伤

Abstract:

Abstract: Objective Study application of M. O. I. S.T. theory in the clinical practice of stage 3 and stage 4 stress injury. Methods A total of 64 patients with stage 3 and stage 4 stress injury who were hospitalized in The Fourth Affiliated Hospital of Guangzhou Medical University from July 2019 to October 2019 were randomly divided into observation group and control group (32 cases in each group) . The control group was treated with vacuum-assisted closure (VAC) and the observation group was treated with VAC combined with continuous micro-oxygen therapy. Results After intervention, the wound shrinkage rate of the observation group was higher than that of the control group (P<0.05). After intervention, the observation group's granulation tissue coverage rate increased, the wound healing rate increased, the wound pain score decreased, the wound bacterial culture rate decreased, the difference was statistically significant (P<0.05) ; After intervention, there were significant differences in wound pH,CD34+T Cell and proliferating cell nuclear antigen (P<0.05). Conclusion VAC combined with microoxygen therapy can accelerate wound area reduction, promote granulation tissue growth and wound healing, reduce wound pain, and reduce wound bacterial residue in patients with pressure ulcer of stage 3 and 4, to improve the pH of the wound and the tissue immunology.

Key words: Vacuum-assisted closure, Continuous microoxygenation, Pressure injury, Wound reduction, Granulation tissue coverage