关键词: 乳癖散结片, 他莫昔芬, 乳腺增生, 孕激素

Abstract:

Objective To study the effect of Rupi Sanjie tablets combined with tamoxifen on progesterone level and long-term prognosis in patients with benign breast hyperplasia. Method 60 patients with benign breast hyperplasia who were diagnosed and treated in the Affiliated Shunde Hospital of Jinan University from November 2019 to November 2020 were randomly divided into two groups (a coin toss random method), with 30 in the control group and 30 in the observation group. The control group was treated with tamoxifen as a single agent, and the observation group was treated with Rupi Sanjie tablets combined with tamoxifen, the effects of progesterone and long-term prognosis between the two groups were compared. Result There was no significant difference in curative effect between the two groups (P ＞ 0.05). The improvement of breast pain time, tumor diameter and serum progesterone level in the observation group was better than that in the control group after treatment, and the difference was statistically significant (P ＜ 0.05). Conclusion Rupi Sanjie tablet combined with tamoxifen has a significant effect in the treatment of benign breast hyperplasia. It can promote the recovery of progesterone as soon as possible.

Key words: Rupi Sanjie tablets, Tamoxifen, Breast hyperplasia, Progesterone