临床普外科电子杂志 ›› 2025, Vol. 13 ›› Issue (4): 19-.

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从第 7 版《日本胃癌治疗指南》看胃癌功能保留手术的进步

  

  1. 同济大学附属东方医院 上海市东方医院 胃肠外科,上海 200120
  • 出版日期:2025-10-01 发布日期:2026-01-29
  • 基金资助:

    上海市浦东新区卫生健康委员会重点学科培育项目(PWZxk2025-04)

Advances in function-preserving gastric cancer surgery: insights from the 7th edition Japanese Gastric Cancer Guidelines

  1. Gastrointestinal Surgery Department of Dongfang Hospital Affiliated to Tongji University, Shanghai East Hospital, Shanghai 200120, China
  • Online:2025-10-01 Published:2026-01-29

摘要:

胃癌作为东亚地区常见的消化道恶性肿瘤,其治疗模式正经历从根治性切除向功能保留的精准治疗的重要转变。2025 年 3 月,第 7 版《日本胃癌治疗指南》发布,该指南对功能保留手术的适应证和技术规范进行了更新,为临床实践提供了重要参考。本文系统梳理了新版指南中关于早期胃癌内镜治疗指征的扩展、各种功能保留术式的技术要点及适应证选择,重点分析了幽门保留胃切除术、近次全胃切除术、近端胃切除抗反流重建技术等功能保留手术的临床应用价值,为我国胃癌功能保留手术的规范化开展提供循证依据和技术参考。

关键词: 胃癌, 功能保留, 近端胃切除

Abstract:

Gastric cancer, a prevalent gastrointestinal malignancy in East Asian countries, particularly Japan, Korea, and China, is undergoing a significant shift in treatment paradigms, moving from radical resection toward function-preserving precision therapy. In March 2025, the 7th edition of the Japanese Gastric Cancer Treatment Guidelines was released, updating the indications and technical standards for function-preserving gastrectomy, thereby providing critical guidance for clinical practice. This article systematically reviews key updates in the new guidelines, including expanded indications for endoscopic treatment of early gastric cancer, technical nuances of various function-preserving procedures, and criteria for selecting appropriate surgical approaches. Special emphasis is placed on the clinical value of pylorus-preserving gastrectomy, subtotal gastrectomy, and anti-reflux reconstruction techniques following proximal gastrectomy. The findings aim to off er evidence-based insights and technical references for standardizing function-preserving gastrectomy in China.

Key words: Gastric cancer, Function-preserving, Proximal gastrectomy