临床普外科电子杂志 ›› 2025, Vol. 13 ›› Issue (2): 54-.

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腹腔镜胆总管切开取石一期缝合术与 T 形管引流术在胆总管结石患者中的疗效对比

  

  1. 盐城市响水县人民医院 普外科,江苏 盐城 224600
  • 出版日期:2025-04-01 发布日期:2025-08-11

Comparison of the therapeutic effects of laparoscopic choledochotomy with one-stage suturing and T-tube drainage in patients with common bile duct stones

  1. Department of General Surgery, Xiangshui County People's Hospital, Yancheng City, Jiangsu 224600
  • Online:2025-04-01 Published:2025-08-11

摘要:

目的 对比腹腔镜胆总管切开取石一期缝合术与 T 形管引流术治疗胆总管结石患者的疗效。方法 选择 2021 年 6 月至 2024 年 5 月盐城市响水县人民医院收治的胆总管结石患者 108 例,采用随机数字表法分为对照组和试验组,各 54 例。两组均实施腹腔镜胆总管切开取石术治疗,对照组给予放置 T 形管引流术,试验组给予一期缝合术。比较两组手术情况及术后恢复指标、血清炎症因子水平、肝功能指标、生活质量及术后并发症发生率。结果 试验组患者的手术时间、术后引流时间、肠道功能恢复时间及住院时间均短于对照组,差异均有显著性(P < 0.001)。两组患者的术中出血量差异无显著性(P > 0.05)。术前,两组患者血清炎症因子水平、肝功能指标及生活质量比较无显著差异(P > 0.05)。术后 48h,试验组患者各炎症因子指标均低于对照组,差异均有显著性(P < 0.05);试验组的丙氨酸转氨酶、天冬氨酸转氨酶水平低于对照组,总胆红素水平高于对照组,差异均有显著性(P < 0.001)。且试验组术后 1 个月生活质量各项评分及总分均高于对照组,差异均有显著性(P < 0.001)。试验组患者总发生率为 3.70%,低于对照组(16.67%),差异有显著性(P < 0.05)。结论 腹腔镜胆总管切开取石一期缝合术疗效优于 T 形管引流术,可减轻术后炎症因子水平,改善肝功能与生活质量,减少术后并发症。

关键词: 腹腔镜, 胆总管切开取石, 一期缝合, T 形管引流术

Abstract:

Objective To compare the efficacy of laparoscopic choledochotomy with one-stage suturing and T-tube drainage in the treatment of patients with common bile duct stones. Method 108 patients with common bile duct stones admitted to Xiangshui County People's Hospital in Yancheng City from June 2021 to May 2024 were selected and randomly divided into two groups of 54 each using a random number table method. Both groups underwent laparoscopic common bile duct stone removal surgery, with the control group receiving T-shaped tube drainage and the experimental group receiving primary suture surgery. Compare the surgical outcomes and postoperative recovery indicators, serum inflammatory factor levels, liver function indicators, quality of life, and incidence of postoperative complications between two groups. Result The experimental group had significantly shorter surgical time, postoperative drainage time, intestinal function recovery time, and hospitalization time compared to the control group (P < 0.001). The intraoperative blood output of the experimental group patients was higher than that of the control group, but the difference was not significant (P > 0.05). Before surgery, there was no significant difference in serum inflammatory cytokine levels, liver function indicators, and quality of life between the two groups of patients (P > 0.05). 48 hours after surgery, all inflammatory factor indicators in the experimental group were significantly lower than those in the control group (P < 0.05); The levels of aspartate transaminase and alanine transaminase in the experimental group were lower than those in the control group, and the level of total bilirubin was higher than that in the control group, with signifi cant diff erences (P < 0.001). And the quality of life scores and total scores of the experimental group were significantly higher than those of the control group one month after surgery (P < 0.001). The total incidence rate of patients in the experimental group was 3.70%, which was lower than that in the control group (16.67%), and the difference was significant (P < 0.05). Conclusion Laparoscopic choledochotomy with one-stage suturing is more effective than T-tube drainage in reducing postoperative inflammatory cytokine levels, improving liver function and quality of life, and reducing postoperative complications.

Key words: Laparoscopy, Cut open the common bile duct to remove stones, First stage suturing, T tube drainage