临床普外科电子杂志 ›› 2025, Vol. 13 ›› Issue (2): 37-.

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瑞马唑仑在甲状腺切除术全身麻醉中的应用效果观察

  

  1. 盐城市建湖县人民医院 麻醉科,江苏 盐城 224700
  • 出版日期:2025-04-01 发布日期:2025-08-07

Observation of the application effect of rimazolen in general anesthesia for thyroidectomy

  1. Anesthesiology Department of Jianhu County People's Hospital in Yancheng City, Jiangsu Yancheng 224700, China
  • Online:2025-04-01 Published:2025-08-07

摘要:

目的 观察瑞马唑仑在甲状腺切除术全身麻醉中的应用及镇静效果。方法 选取 2023 年 2 月至 2024 年 11 月于盐城市建湖县人民医院行甲状腺切除术的 72 例患者,按照随机数字表法分为参照组及研究组,各 36 例。对比两组患者的麻醉效果。结果 给药前,两组患者的脑电双频指数及镇静情况无显著差异(P > 0.05)。镇静后,研究组患者各时段的脑电双频指数与改良警觉 / 镇静评分均低于参照组,差异均有显著性(P < 0.01)。研究组患者的麻醉时间、苏醒时间及麻醉恢复室停留时间均短于参照组,且各时点血糖、肾上腺素及皮质醇水平均低于参照组,差异均有显著性(P < 0.05)。研究组患者的各类不良事件发生率均低于对照组,差异均有显著性(P < 0.05)。结论 在甲状腺切除术中应用瑞马唑仑全身麻醉,有利于合理控制患者麻醉苏醒时间,有效降低患者不良反应发生风险。

关键词: 瑞马唑仑, 全身麻醉, 甲状腺切除术

Abstract:

Objective To observe the application and sedative effect of rimazolen in general anesthesia for thyroidectomy. Method 72 patients who underwent thyroidectomy at Jianhu County People's Hospital in Yancheng City from February 2023 to November 2024 were selected and randomly divided into a reference group and a study group, with 36 patients in each group, using a random number table method. Compare the anesthesia effects of two groups of patients. Result Before administration, there was no significant diff erence in the bispectral index and sedation status between the two groups of patients (P > 0.05). After sedation, the bispectral index and modified observer's assessment of alterness/sedation score of patients in the study group were significantly lower than those in the control group at all time points (P < 0.01). The anesthesia time, awakening time, and duration of stay in the anesthesia recovery room of the study group patients were shorter than those of the control group, and the levels of blood glucose, adrenaline, and cortisol were lower than those of the control group at all time points, with significant differences (P < 0.05). The incidence of various adverse events in the study group was lower than that in the control group, and the differences were significant (P < 0.05). Conclusion The application of rimazolen general anesthesia in thyroidectomy is beneficial for controlling the patient's anesthesia recovery time reasonably and eff ectively reducing the risk of adverse reactions.

Key words: Rimazolen, General anesthesia, Thyroidectomy